Catalog No.
PHB96101
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human PIGR (Arg289-Arg638).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Poly-Ig receptor,Polymeric immunoglobulin receptor,PIgR,PIGR,Hepatocellular carcinoma-associated protein TB6
Purification
Purified by antigen affinity column.
Accession
P01833
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Effect of DNA methylation on inhibitor development in people with hemophilia A treated with FVIII concentrates., PMID:40502981
Construction and validation of antibody dependent cell phagocytosis related risk model in breast cancer., PMID:40442365
Polymeric immunoglobulin receptor (pIgR) in cancer progression: a critical role and potential therapeutic target., PMID:40415061
pIgR-like4.2 enhances the antiviral immune response of zebrafish against spring viremia of carp virus., PMID:40250506
Understanding IgM Structure and Biology to Engineer New Antibody Therapeutics., PMID:40237925
Impact of afatinib on intestinal and salivary IgA: Immune response alterations linked to gastrointestinal side effects., PMID:40228698
Kinetics of pIgR and IgM immune responses in snakehead (Channa argus) to inactivated Aeromonas hydrophila via immersion and intraperitoneal injection., PMID:40169670
Design, Production, and Optimization of Antigen-Specific Recombinant Antitumor Dimeric IgA Antibody., PMID:40029519
PIgR Autoantibody-abundant Circulating Vesicles Contributes to Biliary Injury in Biliary Atresia., PMID:39733605
Supplementation of Parachlorella sp. in feed promote the gut microbiome colonization and fecal IgA response of broiler in both early and late period., PMID:39631282
IgA facilitates the persistence of the mucosal pathogen Helicobacter pylori., PMID:39581230
Benzoic Acid potentiates intestinal IgA response in broiler chickens against Salmonella enterica Serovar Typhimurium infection., PMID:39531802
Immunoglobulin M-based local production in skin-associated lymphoid tissue of flounder (Paralichthys olivaceus) initiated by immersion with inactivated Edwardsiella tarda., PMID:39461396
CD5L associates with IgM via the J chain., PMID:39333069
Antibodies and complement are key drivers of thrombosis., PMID:39226900
IgT-mediated mucosal immunity and microbiota dynamics in snakehead (Channa argus) post Aeromonas veronii TH0426 and Aeromonas hydrophila TPS infection: implications for aquaculture disease management., PMID:39172273
Moderate Aerobic Exercise Induces Homeostatic IgA Generation in Senile Mice., PMID:39125769
SARS-CoV-2 Accessory Protein ORF8 Targets the Dimeric IgA Receptor pIgR., PMID:39066171
BTB and CNC homology 1 deficiency disrupts intestinal IgA secretion through regulation of polymeric immunoglobulin receptor expression., PMID:38981617
The IgA-pIgR System Is Dysregulated in Idiopathic Pulmonary Fibrosis., PMID:38976848
Remodeling of anti-tumor immunity with antibodies targeting a p53 mutant., PMID:38886748
Structural and Biochemical Requirements for Secretory Component Interactions with Dimeric IgA., PMID:38809110
Possible transport routes of IgM to the gut of teleost fish., PMID:38657879
Mucosal immune responses and protective efficacy elicited by oral administration AMP-ZnONPs-adjuvanted inactivated H9N2 virus in chickens., PMID:38330890
Recent advances in the molecular understanding of immunoglobulin A., PMID:38329005
Functional studies with IgM and IgA immunoglobulins: binding to pIgR, FcαμR, FcμR, and CDC activities., PMID:38232051
Antibodies target intracellular oncodrivers through PIGR-mediated transcytosis., PMID:38092884
Identification of the Major Protein Components of Human and Cow Saliva., PMID:38069163
Structural and biochemical requirements for secretory component interactions with dimeric Immunoglobulin A., PMID:38014291
Dimeric IgA specifically disables intracellular mutated oncodrivers., PMID:37967526
Targeting intracellular oncoproteins with dimeric IgA promotes expulsion from the cytoplasm and immune-mediated control of epithelial cancers., PMID:37909039
Polymeric immunoglobulin receptor (pIgR) in cancer., PMID:37897659
High-Pressure Processing of Human Milk: A Balance between Microbial Inactivation and Bioactive Protein Preservation., PMID:37423385
Interferon-γ mediating overexpression of polymeric immunoglobulin receptor in grass carp (Ctenopharyngodon idellus) liver cells., PMID:37257764
Structural basis for Fc receptor recognition of immunoglobulin M., PMID:37095205
Molecular cloning and functional analysis of polymeric immunoglobulin receptor, pIgR, gene in mandarin fish Siniperca chuatsi., PMID:37044186
Single-cell RNA sequencing reveals the immune microenvironment and signaling networks in cystitis glandularis., PMID:36814917
Polymeric immunoglobulin receptor deficiency exacerbates autoimmune hepatitis by inducing intestinal dysbiosis and barrier dysfunction., PMID:36709322
Hepatic pIgR-mediated secretion of IgA limits bacterial translocation and prevents ethanol-induced liver disease in mice., PMID:36690432
Outcomes of nicotinic modulation on markers of intestinal IgA antibody response., PMID:36643694
Microbiota-dependent and -independent postnatal development of salivary immunity., PMID:36640306
When secretion turns into excretion - the different roles of IgA., PMID:36618388
Bacteroides-derived isovaleric acid enhances mucosal immunity by facilitating intestinal IgA response in broilers., PMID:36604758
Intracellular immunoglobulin A (icIgA) in protective immunity and vaccines., PMID:36597220
Mahuang Xixin Fuzi decoction protects the BALB/c-nude mice infected with influenza A virus by reducing inflammatory cytokines storm and weakly regulating SIgA immune response., PMID:36549371
Evolutionary analyses of polymeric immunoglobulin receptor (pIgR) in the mammals reveals an outstanding mutation rate in the lagomorphs., PMID:36466819
Enhancement of intestinal mucosal immunity and immune response to the foot-and-mouth disease vaccine by oral administration of danggui buxue decoction., PMID:36425118
Acute polyethylene microplastic (PE-MPs) exposure activates the intestinal mucosal immune network pathway in adult zebrafish (Danio rerio)., PMID:36419273
M1 macrophages evoke an increase in polymeric immunoglobulin receptor (PIGR) expression in MDA-MB468 breast cancer cells through secretion of interleukin-1β., PMID:36207349
Structural and functional changes of bioactive proteins in donor human milk treated by vat-pasteurization, retort sterilization, ultra-high-temperature sterilization, freeze-thawing and homogenization., PMID:36185694
For research use only. Not for human or drug use.
