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Research Grade Anti-HIV-1 gp120/Glycoprotein 120 (N6LS)

Catalog #:   DVV03105 Specific References (125) DATASHEET
Host species: Human
Isotype: IgG1 (M428L/N434S), kappa
Applications: Research Grade Biosimilar
Expression system: Mammalian Cells
Overview

Catalog No.

DVV03105

Expression system

Mammalian Cells

Species reactivity

Human immunodeficiency virus 1 (HIV-1)

Host species

Human

Isotype

IgG1 (M428L/N434S), kappa

Clonality

Monoclonal

Target

gp120/Glycoprotein 120

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q03805

Applications

Research Grade Biosimilar

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Alternative Names

VRC 609,VRC-HIVMAB091-00-AB (N6LS), N6LS (VRC-HIVMAB091-00-AB)

Clone ID

N6LS

Data Image
  • SDS-PAGE
    SDS PAGE for Anti-HIV-1 gp120/Glycoprotein 120 (N6LS)
References

Sulfated Glycoprotein Synthesis. PMID: 35761038

Inhibitory effects of glycoprotein-120 (G-120) from Ulmus davidiana Nakai on cell growth and activation of matrix metalloproteinases. PMID: 15528991

Plant-originated glycoprotein, G-120, inhibits the growth of MCF-7 cells and induces their apoptosis. PMID: 15811576

The human cell surface glycoprotein complex (gp 120,200) recognized by monoclonal antibody K20 is a component binding to phytohaemagglutinin on T cells. PMID: 3486453

Molecular characterisation of a cDNA sequence encoding the backbone of a style-specific 120 kDa glycoprotein which has features of both extensins and arabinogalactan proteins. PMID: 9426603

The stylar 120 kDa glycoprotein is required for S-specific pollen rejection in Nicotiana. PMID: 16115068

cDNA and deduced amino acid sequence of human PK-120, a plasma kallikrein-sensitive glycoprotein. PMID: 7805892

Cells under siege: viral glycoprotein interactions at the cell surface. PMID: 21440638

Mouse gamete adhesion molecules. PMID: 1536894

A style-specific hydroxyproline-rich glycoprotein with properties of both extensins and arabinogalactan proteins. PMID: 7527273

Variations in the breeding behavior of cichlids and the evolution of the multi-functional seminal plasma protein, seminal plasma glycoprotein 120. PMID: 30572831

Strategies for the purification of P-glycoprotein from multidrug-resistant Chinese hamster ovary cells. PMID: 1687982

Laminin-binding protein 120 from brain is closely related to the dystrophin-associated glycoprotein, dystroglycan, and binds with high affinity to the major heparin binding domain of laminin. PMID: 8325873

Immunological responses to envelope glycoprotein 120 from subtypes of human immunodeficiency virus type 1. PMID: 10408727

Glycoprotein VI is not a Functional Platelet Receptor for Fibrin Formed in Plasma or Blood. PMID: 32492725

Fluorescence "Turn-on" Lectin Sensors Fabricated by Ligand-Assisted Labeling Probes for Detecting Protein-Glycoprotein Interactions. PMID: 31891486

Prospect for prevention of human immunodeficiency virus infection: purified 120-kDa envelope glycoprotein induces neutralizing antibody. PMID: 3018753

Tamm-Horsfall urinary glycoprotein. The chemical composition. PMID: 5493864

A galactose-rich, cell-wall glycoprotein from styles of Nicotiana alata. PMID: 8580973

Secretion of proliferin. PMID: 3780559

Proximity Tagging Identifies the Glycan-Mediated Glycoprotein Interactors of Galectin-1 in Muscle Stem Cells. PMID: 34181849

Structure and function of the selectin ligand PSGL-1. PMID: 10412562

Biosynthesis, processing and half-life of P-glycoprotein in a human multidrug-resistant KB cell. PMID: 2570611

Bullous pemphigoid and linear IgA dermatosis sera recognize a similar 120-kDa keratinocyte collagenous glycoprotein with antigenic cross-reactivity to BP180. PMID: 9077469

The matrix metalloproteinases and their inhibitors. PMID: 1497900

Identification of potential glycoprotein biomarkers in oral squamous cell carcinoma using sweet strategies. PMID: 33547992

Angiogenesis inhibitors generated by tumors. PMID: 8529090

Molecular cloning of cDNAs encoding lamp A, a human lysosomal membrane glycoprotein with apparent Mr approximately equal to 120,000. PMID: 3131762

Production of Recombinant Rabies Virus Glycoprotein by Insect Cells in a Single-Use Fixed-Bed Bioreactor. PMID: 28921430

Distinct P-glycoprotein precursors are overproduced in independently isolated drug-resistant cell lines. PMID: 2897689

Identification of a 120-kD surface glycoprotein distinguishing cultured superior cervical ganglion from ciliary ganglion neurons. PMID: 2335135

Zinc-α-2-glycoprotein: a candidate biomarker for colon cancer diagnosis in Chinese population. PMID: 25561225

Glycoproteins of the lysosomal membrane. PMID: 3922993

Dystrophin-glycoprotein complex purified from hamster cardiac muscle. Comparison of the complexes from cardiac and skeletal muscles of hamster and rabbit. PMID: 9004166

Purification and characterization of a prokaryotic glycoprotein from the cell envelope of Halobacterium salinarium. PMID: 1270419

Syndecans play dual roles as cell adhesion receptors and docking receptors. PMID: 22659189

Identification and purification of a cell surface glycoprotein mediating intercellular adhesion in embryonic and adult tissue. PMID: 6352050

Association between Higher Circulating Leucine-Rich α-2 Glycoprotein 1 Concentrations and Specific Plasma Ceramides in Postmenopausal Women with Type 2 Diabetes. PMID: 35883498

Derived protein sequence, oligosaccharides, and membrane insertion of the 120-kDa lysosomal membrane glycoprotein (lgp120): identification of a highly conserved family of lysosomal membrane glycoproteins. PMID: 3174652

Characterization of a glycoprotein fusogen isolated from Sendai virus. PMID: 6318835

Pregnancy specific beta 1-glycoprotein in human intestine. PMID: 8487756

Differential overexpression of three mdr gene family members in multidrug-resistant J774.2 mouse cells. Evidence that distinct P-glycoprotein precursors are encoded by unique mdr genes. PMID: 2473069

N-glycoprotein SRMAtlas: a resource of mass spectrometric assays for N-glycosites enabling consistent and multiplexed protein quantification for clinical applications. PMID: 23408683

A phosphatidylinositol-linked peanut agglutinin-binding glycoprotein in central nervous system myelin and on oligodendrocytes. PMID: 3283151

Assembly of arenavirus envelope glycoprotein GPC in detergent-soluble membrane microdomains. PMID: 19625404

Halobacterial glycoprotein saccharides contain covalently linked sulphate. PMID: 7439381

Evaluation of soluble glycoprotein V as an in vitro quality marker for platelet concentrates: a correlation study between in vitro platelet quality markers and the effect of storage medium. PMID: 27060862

Rat liver membranes contain a 120 kDa glycoprotein which serves as a substrate for the tyrosine kinases of the receptors for insulin and epidermal growth factor. PMID: 3542568

Alternate overexpression of two P-glycoprotein [corrected] genes is associated with changes in multidrug resistance in a J774.2 cell line. PMID: 2570778

A novel seminal plasma glycoprotein of a teleost, the Nile tilapia (Oreochromis niloticus), contains a partial von Willebrand factor type D domain and a zona pellucida-like domain. PMID: 11933161

Isolation of a human biliary glycoprotein inhibitor of cholesterol crystallization. PMID: 8425696

Factors affecting plasma pregnancy-associated glycoprotein 1 concentrations throughout gestation in high-producing dairy cows. PMID: 18992084

Effects of beta2-glycoprotein-I on platelet aggregation in cord versus adult whole blood. PMID: 17365850

Characterization of human middle ear mucus glycoprotein in chronic secretory otitis media (CSOM). PMID: 3427782

Bovine coronavirus structural proteins. PMID: 7086972

Production of a sialylated N-linked glycoprotein in insect cells. PMID: 11587569

Complementary deoxyribonucleic acid cloning and molecular characterization of an estrogen-dependent human oviductal glycoprotein. PMID: 7819450

Studies on the "insoluble" glycoprotein complex from human colon. Identification of reduction-insensitive MUC2 oligomers and C-terminal cleavage. PMID: 10336486

GRASP: a novel heparin-binding serum glycoprotein that mediates oligodendrocyte-substratum adhesion. PMID: 7533846

Consequences of the interaction of platelet membrane glycoprotein GPIIb-IIIa (alpha IIb beta 3) and its ligands. PMID: 1500819

Effect of ethanol on gastric mucus glycoprotein synthesis, translocation, transport, glycosylation, and secretion. PMID: 9161600

Disulphide bonds and the 118,000 Mr glycoprotein of human intestinal mucin. PMID: 2641411

[Osteoclastogenesis inhibitory factor (OCIF)/OPG]. PMID: 9648461

Rat prominin, like its mouse and human orthologues, is a pentaspan membrane glycoprotein. PMID: 11467842

Current status and strategies for vaccines against diseases induced by human T-cell lymphotropic retroviruses (HTLV-I, -II, -III). PMID: 2410115

Synthesis and processing of glycoprotein gG of herpes simplex virus type 2. PMID: 2987534

Humoral immune response to a 200-kDa glycoprotein antigen of Saccharomyces cerevisiae is common in man. PMID: 9657263

Characterization of equine zona pellucida glycoproteins by polyacrylamide gel electrophoresis and immunological techniques. PMID: 1285065

Physiological Corticosterone Attenuates gp120-Mediated Microglial Activation and Is Associated with Reduced Anxiety-Like Behavior in gp120-Expressing Mice. PMID: 36851638

A Trichomonas vaginalis 120 kDa protein with identity to hydrogenosome pyruvate:ferredoxin oxidoreductase is a surface adhesin induced by iron. PMID: 15659068

Purification of the 110-kilodalton glycoprotein receptor for mouse hepatitis virus (MHV)-A59 from mouse liver and identification of a nonfunctional, homologous protein in MHV-resistant SJL/J mice. PMID: 2164599

Purification, crystallization and X-ray diffraction study of extracellular dermal glycoprotein from carrot and the inhibition complex that it forms with an endo-β-glucanase from Aspergillus aculeatus. PMID: 21795806

Characterization of a membrane-associated glycoprotein complex implicated in cell adhesion to fibronectin. PMID: 4055919

SC1, a SPARC-related glycoprotein, exhibits features of an ECM component in the developing and adult brain. PMID: 8724975

A novel proline-rich glycoprotein associated with the extracellular matrix of vascular bundles of Brassica petioles. PMID: 9177049

Immunoinformatic-driven design and evaluation of multi-epitope mRNA vaccine targeting HIV-1 gp120., PMID:40433366

Vaccination of nonhuman primates elicits a broadly neutralizing antibody lineage targeting a quaternary epitope on the HIV-1 Env trimer., PMID:40339576

Isolation and structure elucidation of Dm-CVNH, a new cyanovirin-N homolog with activity against SARS-CoV-2 and HIV-1., PMID:39956341

Safety and Immunogenicity of a DNA Vaccine With Subtype C gp120 Protein Adjuvanted With MF59 or AS01B: A Phase 1/2a HIV-1 Vaccine Trial., PMID:38916429

Methamphetamine Enhancement of HIV-1 gp120-Mediated NLRP3 Inflammasome Activation and Resultant Proinflammatory Responses in Rat Microglial Cultures., PMID:38612400

Methamphetamine enhancement of HIV-1 gp120-mediated NLRP3 inflammasome activation and resultant proinflammatory responses in rat microglial cultures., PMID:38168345

P2Y13 receptor involved in HIV-1 gp120 induced neuropathy in superior cervical ganglia through NLRP3 inflammasome activation., PMID:38142931

Plasma Human Immunodeficiency Virus 1 Soluble Glycoprotein 120 Association With Correlates of Immune Dysfunction and Inflammation in Antiretroviral Therapy-Treated Individuals With Undetectable Viremia., PMID:38035854

Protein Dose-Sparing Effect of AS01B Adjuvant in a Randomized Preventive HIV Vaccine Trial of ALVAC-HIV (vCP2438) and Adjuvanted Bivalent Subtype C gp120., PMID:37795976

Additional boosting to the RV144 vaccine regimen increased Fc-mediated effector function magnitude but not durability., PMID:37260254

Indoline CD4-mimetic compounds mediate potent and broad HIV-1 inhibition and sensitization to antibody-dependent cellular cytotoxicity., PMID:36961924

Aptamer-linked photonic crystal hydrogel sensor for rapid point-of-care detection of human immuno-deficiency virus-1 (HIV-1)., PMID:36827736

Myomedin replicas of gp120 V3 loop glycan epitopes recognized by PGT121 and PGT126 antibodies as non-cognate antigens for stimulation of HIV-1 broadly neutralizing antibodies., PMID:36569830

HIV-1 gp120 Protein Activates Cyclin-Dependent Kinase 1, a Possible Link to Central Nervous System Cell Death., PMID:36560797

Identification of human immunodeficiency virus -1 E protein-targeting lead compounds by pharmacophore based screening., PMID:36517066

Pharmacokinetics, metabolism and excretion of radiolabeled fostemsavir administered with or without ritonavir in healthy male subjects., PMID:36083110

Behavioral Evidence for a Tau and HIV-gp120 Interaction., PMID:35628323

NMDA receptor antagonists engender neuroprotection against gp120-induced cognitive dysfunction in rats through modulation of PKR activation, oxidative stress, ER stress and IRE1α signal pathway., PMID:35543645

Methamphetamine augments HIV-1 gp120 inhibition of synaptic transmission and plasticity in rat hippocampal slices: Implications for methamphetamine exacerbation of HIV-associated neurocognitive disorders., PMID:35337950

Win55,212-2 improves neural injury induced by HIV-1 glycoprotein 120 in rats by exciting CB2R., PMID:35157986

Red Algal Sulfated Galactan Binds and Protects Neural Cells from HIV-1 gp120 and Tat., PMID:34451811

Chemical Compounds and Computational Prediction of Their Inhibitory Effects on the HIV-1 gp120 Receptor by Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes), with Antler-Like Morphology of Fruiting Bodies., PMID:34375519

Aptamer Laden Liquid Crystals Biosensing Platform for the Detection of HIV-1 Glycoprotein-120., PMID:34068186

Liquid Crystal Based Binding Assay for Detecting HIV-1 Surface Glycoprotein., PMID:33981675

In silico analysis of molecular interactions between HIV-1 glycoprotein gp120 and TNF receptors., PMID:33813078

Sulfoglycodendrimer Therapeutics for HIV-1 and SARS-CoV-2., PMID:33786368

Magnetic Nanoparticle and Exosomal Therapeutic (M-NEXT) Effects on HIV-Associated Neurotoxicity., PMID:33389896

The barley lectin, horcolin, binds high-mannose glycans in a multivalent fashion, enabling high-affinity, specific inhibition of cellular HIV infection., PMID:32636304

Role of nanoscale antigen organization on B-cell activation probed using DNA origami., PMID:32601450

The development of a predictive model to identify potential HIV-1 attachment inhibitors., PMID:32421648

HIV gp120 Induces the Release of Proinflammatory, Angiogenic, and Lymphangiogenic Factors from Human Lung Mast Cells., PMID:32375243

Schwann cell-derived CXCL1 contributes to human immunodeficiency virus type 1 gp120-induced neuropathic pain by modulating macrophage infiltration in mice., PMID:32229220

HIV long-term non-progressors share similar features with simian immunodeficiency virus infection of chimpanzees., PMID:32223527

Fostemsavir in Adults with Multidrug-Resistant HIV-1 Infection., PMID:32212519

Landscapes of binding antibody and T-cell responses to pox-protein HIV vaccines in Thais and South Africans., PMID:31999736

Association of complement C3d receptor 2 genotypes with the acquisition of HIV infection in a trial of recombinant glycoprotein 120 vaccine., PMID:31634193

R5 HIV-1 gp120 Activates p38 MAPK to Induce Rat Cardiomyocyte Injury by the CCR5 Coreceptor., PMID:31574524

Immunogenicity of RNA Replicons Encoding HIV Env Immunogens Designed for Self-Assembly into Nanoparticles., PMID:31515132

Variability OF HIV-1 V2 env domain for integrin binding: Clinical correlates., PMID:31357165

Methadone and buprenorphine pharmacokinetics and pharmacodynamics when coadministered with fostemsavir to opioid-dependent, human immunodeficiency virus seronegative participants., PMID:30980734

Sex Differences in a Rodent Model of HIV-1-Associated Neuropathic Pain., PMID:30857270

Effects of HIV-1 gp120 and TAT-derived microvesicles on endothelial cell function., PMID:30789287

Supraspinal interaction between HIV-1-gp120 and cannabinoid analgesic effectiveness., PMID:30008083

Structural discordance in HIV-1 Vpu from brain isolate alarms amyloid fibril forming behavior- a computational perspective., PMID:29705491

Interferon-β induced in female genital epithelium by HIV-1 glycoprotein 120 via Toll-like-receptor 2 pathway acts to protect the mucosal barrier., PMID:29553138

Efaverinz and nano-gold-loaded mannosylated niosomes: a host cell-targeted topical HIV-1 prophylaxis via thermogel system., PMID:29231058

Construction and Production of HIV-VLP Harboring MPER-V3 for Potential Vaccine Study., PMID:29046160

Effects of nanoparticle-encapsulated curcumin on HIV-gp120-associated neuropathic pain induced by the P2X3 receptor in dorsal root ganglia., PMID:28962965

Peroxisome proliferator-activated receptor-gamma: potential molecular therapeutic target for HIV-1-associated brain inflammation., PMID:28886715

Improving the Immunogenicity of Native-like HIV-1 Envelope Trimers by Hyperstabilization., PMID:28834745

Datasheet
$ 328
Product specifications
100 μg 328 1 mg 1314

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For research use only. Not for human or drug use.

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Research Grade Anti-HIV-1 gp120/Glycoprotein 120 (N6LS) [DVV03105]
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