Anti-Human oxLDL Antibody (SAA0552)

Catalog No.

RHK09902

Species reactivity

Human, Mouse, Rat

Host species

Mouse

Isotype

IgG2a

Clonality

Monoclonal

Target

oxidised LDL, oxidised form of low-density lipoprotein (LDL), oxidised low-density lipoproteins, oxidized low-density lipoprotein, oxidized low-density lipoproteins, OxLDL

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Applications

ELISA, FCM, IHC

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

SAA0552

Ertugliflozin attenuates atherosclerosis in nondiabetic ApoE-/- mice by upregulating ABCA1 and LDLR via the PPARγ/LXRα pathway., PMID:40419168

A novel NFKB1 agonist remodels tumor microenvironment and activates dendritic cells to promote anti-tumor immunity in colorectal cancer., PMID:40394677

Dyslipidemia is associated with increased NK cell cytotoxicity and autoimmunity in women with recurrent pregnancy losses., PMID:40372127

Anti-Oxidized Low-Density Lipoprotein Antibodies Before and After Intravenous Immunoglobulin Therapy in Kawasaki Disease　- Evidence for a Potentially Protective Role., PMID:40352122

Orticumab: the potential to harness oxidized LDL to reduce coronary inflammation with plaque-targeted therapy., PMID:40293233

Development of Fully Human Antibodies Targeting SIRPα and PLA2G7 for Cancer Therapy., PMID:40136470

Immunotherapy and vaccine-based approaches for atherosclerosis prevention: a systematic review study., PMID:40114074

GOLM1 Promotes Atherogenesis by Activating Macrophage EGFR-ERK Signaling Cascade., PMID:40026146

Discovery and in vitro characterization of a human anti-CD36 scFv., PMID:39967671

Anti-Endoglin monoclonal antibody prevents the progression of liver sinusoidal endothelial inflammation and fibrosis in MASH., PMID:39889923

Design of hybrid aptamer-molecularly imprinted polymer nanoparticles for selective binding of oxidized low-density lipoprotein in an ELISA-mimic system., PMID:39832470

Overview of Clinical Relevance of Antibodies Against Oxidized Low-Density Lipoprotein (oLAb) Within Three Decades by ELISA Technology., PMID:39765889

Antibodies Against Phosphorylcholine in Prediction of Cardiovascular Disease Among Women: A Population-Based Prospective Cohort Study., PMID:39741640

Identification of plasma proteins binding oxidized phospholipids using pull-down proteomics and OxLDL masking assay., PMID:39566852

Comparative analysis of Lox-1 and CD36 expression in human platelets and on circulating microparticles during ARDS-induced coagulopathy., PMID:39546984

The Effects of the oxLDL/β2GPI/anti-β2GPI Complex on Macrophage Autophagy and its Mechanism., PMID:39508636

Risk stratification analysis of recurrent myocardial infarction in Indian population using inflammatory, lipid, thrombotic and extracellular matrix remodeling markers., PMID:39351476

Siglec-5 as a novel receptor mediates endothelial cells oxLDL transcytosis to promote atherosclerosis., PMID:39341359

Novel protocol for the transcriptomic analysis of endothelial extracellular vesicles in atherosclerosis., PMID:39271430

Oxidised low-density lipoprotein and antibodies against oxidised low-density lipoprotein in patients with antiphospholipid syndrome., PMID:39212138

Increased vascular deposition of oxidized LDL in untreated juvenile dermatomyositis., PMID:39118148

Hypersensitivity to man-made electromagnetic fields (EHS) correlates with immune responsivity to oxidative stress: a case report., PMID:39108419

Differential Effects of LOX-1 Inhibition on Aortic Structure and Posterior Cerebral Artery Structure and Function in an Experimental Model of Preeclampsia., PMID:38858329

Fcα Receptor Type I and Its Association with Atherosclerosis Development., PMID:38855431

Trem2 Agonist Reprograms Foamy Macrophages to Promote Atherosclerotic Plaque Stability-Brief Report., PMID:38695172

Primary Sjögren's syndrome independently promotes premature subclinical atherosclerosis., PMID:38663882

Nalmefene, an opioid receptor modulator, aggravates atherosclerotic plaque formation in apolipoprotein E knockout mice by enhancing oxidized low-density lipoprotein uptake in macrophages., PMID:38560051

Inhibition of oxidized low-density lipoprotein with orticumab inhibits coronary inflammation and reduces residual inflammatory risk in psoriasis: a pilot randomized, double-blind placebo-controlled trial., PMID:38523341

We Must Abandon the Myth: Oxidized Low-density Lipoprotein is not a Lipoprotein that Plays a Key Role in Atherogenesis., PMID:38494931

Impact of RYGB surgery on plasma immunoglobulins: association between blood pressure and glucose levels six months after surgery., PMID:38149431

Stent composition and immune response after long-term coronary angioplasty., PMID:37934202

Two decades of vaccine development against atherosclerosis., PMID:37860053

Antibodies against oxidized LDL and atherosclerosis in rheumatoid arthritis patients treated with biological agents: a prospective controlled study., PMID:37642764

Increased extracellular vesicles (EVs) related to T cell-mediated inflammation and vascular function in familial hypercholesterolemia., PMID:37637934

Placenta-Derived Extracellular Vesicles From Preeclamptic Pregnancies Impair Vascular Endothelial Function via Lectin-Like Oxidized LDL Receptor-1., PMID:37615097

Development of LOX-1 Antibody Modified Immuno-liposomes as Drug Carriers to Macrophages in Atherosclerotic Lesions., PMID:37592420

Overexpression of LOX-1 in hepatocytes protects vascular smooth muscle cells from phenotype transformation and wire injury induced carotid neoatherosclerosis through ALOX15., PMID:37468019

Possible roles of human mast cells in the formation of xanthelasma palpebrarum., PMID:37341622

Effect of Proprotein Convertase Subtilisin/Kexin Type 9 Inhibition on Podocytes in Mouse Nephrotic Syndrome., PMID:37331628

Limited Association between Antibodies to Oxidized Low-Density Lipoprotein and Vascular Affection in Patients with Established Systemic Lupus Erythematosus., PMID:37240332

Oxidized LDL receptors: a recent update., PMID:37171285

The Oxidized Lipoproteins In Vivo: Its Diversity and Behavior in the Human Circulation., PMID:36982815

Efficacy of Hydroxytyrosol-Rich Food Supplements on Reducing Lipid Oxidation in Humans., PMID:36982623

Cellular FXIII in Human Macrophage-Derived Foam Cells., PMID:36902231

Efficacy of oligodendrocyte precursor cells as delivery vehicles for single-chain variable fragment to misfolded SOD1 in ALS rat model., PMID:36874245

Further analysis of natural antibodies against ischemic stroke., PMID:36741286

Lectin-Like Oxidized Low-Density Lipoprotein Receptor 1 Inhibition in Type 2 Diabetes: Phase 1 Results., PMID:36688371

Increased carotid intima-media thickening and antioxidized low-density lipoprotein in an anti-Ro60 SLE autoantibody subset., PMID:39055110

Oxidized LDL is stable in human serum under extended thawed-state conditions ranging from -20 °C to room temperature., PMID:36578466

Role of CD36 in cancer progression, stemness, and targeting., PMID:36568966

Document Download

Anti-Human oxLDL Antibody (SAA0552).pdf