Catalog No.
RHJ92901
Host species
Human
Isotype
IgG1 CH1-IgG2 Fc Fragment, kappa
Clonality
Monoclonal
Target
Human IgG1 CH1-IgG2 Fc Fragment,kappa
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Applications
FCM, Isotype Control, In vivo Control
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
HyHEL-10
HIV Broadly Neutralizing Antibodies Expressed as IgG3 Preserve Neutralization Potency and Show Improved Fc Effector Function., PMID:34566999
Fc glycan sialylation of biotherapeutic monoclonal antibodies has limited impact on antibody-dependent cellular cytotoxicity., PMID:34355537
Lymphocyte predominant cells detect Moraxella catarrhalis-derived antigens in nodular lymphocyte-predominant Hodgkin lymphoma., PMID:32424289
Characterization of therapeutic antibody fragmentation using automated capillary western blotting as an orthogonal analytical technique., PMID:31271455
Cytosolic Internalization of Anti-DNA Antibodies by Human Monocytes Induces Production of Pro-inflammatory Cytokines Independently of the Tripartite Motif-Containing 21 (TRIM21)-Mediated Pathway., PMID:30233598
Changes of urinary bladder contractility in high-fat diet-fed mice: the role of tumor necrosis factor-α., PMID:24661252
Inhibition of the inflammatory cytokine tumor necrosis factor-alpha with etanercept provides protection against lethal H1N1 influenza infection in mice., PMID:24373231
Suggestive evidence that Fc variants of IgG2 and FcγRIIa loci interact to contribute to the risk of prostate cancer., PMID:23994584
Identification of non-canonical NF-κB signaling as a critical mediator of Smac mimetic-stimulated migration and invasion of glioblastoma cells., PMID:23538445
Characterization of murine anti-human Fab antibodies for use in an immunoassay for generic quantification of human Fab fragments in non-human serum samples including cynomolgus monkey samples., PMID:23017233
Epistatic interactions between Fc (GM) and FcγR genes and the host control of human immunodeficiency virus replication., PMID:22213007
An Fcγ receptor-dependent mechanism drives antibody-mediated target-receptor signaling in cancer cells., PMID:21251615
Lymphotoxin α stimulates proliferation and pro-inflammatory cytokine secretion of rheumatoid arthritis synovial fibroblasts., PMID:21111629
Tumor necrosis factor-alpha antagonist etanercept decreases blood pressure and protects the kidney in a mouse model of systemic lupus erythematosus., PMID:20696988
Searching for NF-kappaB-based treatments of ischemia reperfusion injury., PMID:19842907
Nuclear factor-kappaB activation in axons and Schwann cells in experimental sciatic nerve injury and its role in modulating axon regeneration: studies with etanercept., PMID:19458540
Recombinant human IgG antibodies against human cytomegalovirus., PMID:19133610
TNF-alpha inhibition reduces renal injury in DOCA-salt hypertensive rats., PMID:17989143
Inhibition of TNF-alpha reduces myocardial injury and proinflammatory pathways following ischemia-reperfusion in the dog., PMID:17204912
Assessment of tumor necrosis factor alpha blockade as an intervention to improve tolerability of dose-intensive chemotherapy in cancer patients., PMID:16622259
[Generation of human recombinant antibody Fab fragment and its IgG to adeno-associated virus type II from phage display library]., PMID:15340567
[Baculovirus expression of two human recombinant neutralizing IgG monoclonal antibodies to hepatitis A virus]., PMID:15340519
RANK-Fc: a therapeutic antagonist for RANK-L in myeloma., PMID:12548579
Immunosuppressive treatment protects against angiotensin II-induced renal damage., PMID:12414515
Nonsteroidal anti-inflammatory drugs prevent early diabetic retinopathy via TNF-alpha suppression., PMID:11821258
Analysis of monoclonal rheumatoid factors obtained from the B-cell repertoire in rheumatoid arthritis., PMID:1310812
For research use only. Not for human or drug use.
