Anti-INS Polyclonal Antibody

Catalog No.

PHB94001

Species reactivity

Human, Mouse, Rat

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human INS (Phe25-Asn110).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

INS,Insulin

Purification

Purified by antigen affinity column.

Accession

P01308

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Autoantibodies Targeting Vinculin Reveal Novel Insight into the Mechanisms of Autoimmune Podocytopathies., PMID:40463498

Synaptotoxic effects of extracellular tau are mediated by its microtubule-binding region., PMID:40455293

Preparation of minicircle DNA vectors for gene knock-in to mammalian cells., PMID:40447492

Practice-changing updates on multiple myeloma: highlights from the 2024 ASH annual meeting., PMID:40361170

Genotype, Phenotype, and Clinical Characteristics of Maturity-onset Diabetes of the Young (MODY): Predominance of GCK-MODY., PMID:40338033

Human Endogenous Retroviruses as Novel Therapeutic Targets in Neurodegenerative Disorders., PMID:40333317

Entry Efficiency, Protease Dependence, and Antibody-Mediated Neutralization of SARS-CoV-2 Sublineages KP.3.1.1 and XEC., PMID:40333265

Antibody reactivity in cerebrospinal fluid and serum against the insulin-insulin-like growth factor 2 (INS-IGF2) protein is associated with psychotic symptomatology in patients with schizophrenia or related psychosis., PMID:40319454

GLP- 1R status using validated monoclonal antibody in 689 cases of neuroendocrine neoplasm and its correlation with somatostatin receptor scintigraphy, insulin production, and histological grades., PMID:40281248

PrP C -induced signaling in human neurons activates phospholipase Cɣ1 and an Arc/Arg3.1 response., PMID:40236043

[The highlights of nephrology in 2024]., PMID:40208671

Deciphering HIV vaccine-induced antibody response according to ethnicity., PMID:40162984

Comparison of B lymphocyte profile between membranous nephropathy and idiopathic nephrotic syndrome pediatric patients., PMID:40122944

Outcomes of Newly Diagnosed Multiple Myeloma Patients Requiring Dialysis., PMID:40122729

Current Treatment Strategies for Multiple Myeloma at First Relapse., PMID:40095642

Effects of feeding different proportions of steam-flaked corn-based starter on growth performance, immunity and serum metabolism of pre-weaned Simmental calves., PMID:39877733

Changes in Serum Immunoglobulin Levels Play as Predictors of Treatment Response and Prognosis in Pediatric Idiopathic Nephrotic Syndrome During the Remission Phase., PMID:39871511

Pan-neurofascin autoimmune nodoparanodopathy: A case report and literature review., PMID:39854764

Successful Switch to Obinutuzumab in a Rituximab-Intolerant Child with Difficult-to-Treat Idiopathic Nephrotic Syndrome., PMID:39797329

Permanent Neonatal Diabetes with High Insulin Requirements Due to a New Variant in the INS Gene., PMID:39710984

Comparative Analysis of Host Cell Entry Efficiency and Neutralization Sensitivity of Emerging SARS-CoV-2 Lineages KP.2, KP.2.3, KP.3, and LB.1., PMID:39591139

Neutralizing antibody correlate of protection against severe-critical COVID-19 in the ENSEMBLE single-dose Ad26.COV2.S vaccine efficacy trial., PMID:39532861

Molecular and clinical profiles of pediatric monogenic diabetes subtypes: comprehensive genetic analysis of 138 patients., PMID:39504571

Beta cell-specific PAK1 enrichment ameliorates diet-induced glucose intolerance in mice by promoting insulin biogenesis and minimising beta cell apoptosis., PMID:39404845

Serologic Evidence for Early SARS-CoV-2 Circulation in Lima, Peru, 2020., PMID:39353444

Rapid generation of homozygous fluorescent knock-in human cells using CRISPR-Cas9 genome editing and validation by automated imaging and digital PCR screening., PMID:39304762

SARS-CoV-2 seroprevalence and preeclampsia markers in Mozambican pregnant women with perinatal loss., PMID:39300353

CoronaVac-vaccinated kidney transplant recipients with hybrid immunity have strong neutralizing responses against Omicron and Mu variants of SARS-CoV-2., PMID:39254799

Neocortical cholinergic pathology after neonatal brain injury is increased by Alzheimer's disease-related genes in mice., PMID:39111704

Safety and effectiveness of disease-modifying therapies after switching from natalizumab., PMID:39054846

B Cell-activating factor (BAFF): A promising trans-nosographic biomarker of inflammation and autoimmunity in bipolar disorder and schizophrenia., PMID:39047848

SARS-CoV-2 in Mozambican primary school-aged children at Maputo City and Province: a cross-sectional study from a low-income country., PMID:38956534

High SARS-CoV-2 Exposure in Rural Southern Mozambique After Four Waves of COVID-19: Community-Based Seroepidemiological Surveys., PMID:38838093

Evaluation of naturally acquired immune responses against novel pre-erythrocytic Plasmodium vivax proteins in a low endemic malaria population located in the Peruvian Amazon Basin., PMID:38783317

Direct comparison of SARS-CoV-2 variant specific neutralizing antibodies in human and hamster sera., PMID:38762525

Clinical and Laboratory Characteristics of MODY Cases, Genetic Mutation Spectrum and Phenotype-genotype Relationship., PMID:38665000

Two recurrent types of IGH::5' BCL2 breakpoints representing cytogenetic ins(14;18)(q32;q21q21) and t(14;18)(q32;q21), mediated by the VDJ and class switch recombination processes, respectively., PMID:38608254

Induction of islet autoimmunity to defective ribosomal product of the insulin gene as neoantigen after anti-cancer immunotherapy leading to autoimmune diabetes., PMID:38596681

Idiopathic nephrotic syndrome in Syrian children: clinicopathological spectrum, treatment, and outcomes., PMID:38587559

Immunochemical Recognition of Bothrops rhombeatus Venom by Two Polyvalent Antivenoms., PMID:38535818

Shared and distinct genetics of pure type 1 diabetes and type 1 diabetes with celiac disease, homology in their auto-antigens and immune dysregulation states: a study from North India., PMID:38483572

Common single-base insertions in the VNTR of the carboxyl ester lipase (CEL) gene are benign and also likely to arise somatically in the exocrine pancreas., PMID:38483348

Immunological Cross-Reactivity and Preclinical Assessment of a Colombian Anticoral Antivenom against the Venoms of Three Micrurus Species., PMID:38393182

Maturity-onset diabetes of the young type 10 caused by an Ala2Thr mutation of INS: A case report., PMID:38222789

SARS-CoV-2 BA.2.86 enters lung cells and evades neutralizing antibodies with high efficiency., PMID:38194966

Yellow fever vaccine-associated neurologic and viscerotropic disease: a 10-year case series of the French National Reference Center for Arboviruses with clinical and immunological insights., PMID:38123499

Screening of Mutations in Maturity-onset Diabetes of the Young-related Genes and RFX6 in Children with Autoantibody-negative Type 1 Diabetes Mellitus., PMID:38054414

The extrafollicular B cell response is a hallmark of childhood idiopathic nephrotic syndrome., PMID:37996443

Clinical, biological, electrophysiological and therapeutic profile of patients with anti-MAG neuropathy according to MYD88L265P and CXCR4 mutations and underlying haemopathy., PMID:37979093

Luciola mingrelica firefly luciferase as a marker in bioluminescent immunoassays., PMID:37975007

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