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InVivoMAb Anti-Human thrombin Antibody (Iv0119)

Catalog #:   VHB87401 Specific References (50) DATASHEET
Host species: Human
Isotype: IgG4
Applications: ELISA, Neutralization
Accession: P00734
Overview

Catalog No.

VHB87401

Species reactivity

Human

Host species

Human

Isotype

IgG4

Clonality

Monoclonal

Target

F2, Coagulation factor II, Prothrombin,thrombin

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P00734

Applications

ELISA, Neutralization

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

Iv0119

Data Image
References

Model-informed drug development of Mim8 - a next-generation bispecific antibody for treatment of haemophilia A., PMID:40490062

The distinct effect between Amyloid β (1‒40) and Amyloid β (1‒42) on the TRAP-stimulated platelet activation in diabetes mellitus., PMID:40436763

Structural basis of G-quadruplex recognition by a camelid antibody fragment., PMID:40433978

Consistent Killers: Conservation of Thrombin-Like Action on Fibrinogen by Bushmaster (Lachesis Species) Venoms Underpins Broad Antivenom Cross-Reactivities., PMID:40423307

RNAi targeting heparin cofactor II promotes hemostasis in a canine model of acquired hemophilia A., PMID:40413293

Diagnostic value of blood coagulation index in obstetric antiphospholipid syndrome and its subtypes., PMID:40409231

In vitro effects of Mim8 and combined Mim8-bypassing therapy on thrombin generation, thromboelastography and fibrin clot ultrastructure., PMID:40398047

Evaluating the Safety and Efficacy of Concizumab in Hemophilia A/B Patients: A Systematic Review., PMID:40368339

Factor XI and Atrial Fibrillation: A Mismatched Pairing?, PMID:40309219

Recombinant Activated Factor VIIa Combined With Tranexamic Acid Control Haemostasis in Patients With Severe Factor XI Deficiency Undergoing Urological Procedures., PMID:40298276

Bite First, Bleed Later: How Philippine Trimeresurus Pit Viper Venoms Hijack Blood Clotting., PMID:40278683

Case Report: Anti-platelet factor 4 -mediated immunothrombosis in a patient with ANCA vasculitis - a shared mechanism of NETosis., PMID:40276517

HMGB1 derived from macrophages and enteric glial cells contributes to the butyrate-induced colonic hypersensitivity in mice., PMID:40274181

Revolutionizing Treatment Strategies through Inhibition of Tissue Factor Pathway Inhibitor: A Promising Therapeutic Approach for Hemophilia Management., PMID:40200623

Insights from in vitro global assays on possible doses of concomitant hemostatic agents in the presence of NXT007 in hemophilia A., PMID:40199443

Enhancing hemostasis potency in hemophilia with a small interfering ribonucleic acid targeting protein S., PMID:40154791

A Novel Human Anti-FV mAb as a Potential Tool for Diagnostic and Coagulation Inhibitory Approaches., PMID:40141363

Identification and characterization of factor XI autoantibodies in 2 patients with systemic lupus erythematosus: insights into mechanisms of acquired factor XI deficiency., PMID:40129563

Significant attenuation of fully automated thrombin generation in newly diagnosed multiple myeloma patients after induction therapy., PMID:40064842

Clinical Profile of Cerebral Sinus Venous Thrombosis: A Prospective Observational Study in South India., PMID:40058869

Anticoagulant drugs targeting factor XI/XIa and coagulation tests: we urgently need reliable pharmacodynamic data., PMID:40056986

Tissue Factor Pathway-Driven Initial Thrombin Generation is Associated with Hypercoagulability in Obesity., PMID:40049601

Autoantibody Profiles and Prognostic Significance in Severe Fever With Thrombocytopenia Syndrome (SFTS) Patients., PMID:39995275

Guidance-Based Appropriateness of Hemostasis Testing in the Acute Setting., PMID:39970900

Stimulation of endothelin-1 production by autoantibodies present in patients with scleroderma renal crisis., PMID:39956166

Platelet lipidomics indicates enhanced thrombocyte activation in patients with antiphospholipid syndrome in vivo., PMID:39952362

Constructing a logistic regression-based prediction model for subsequent early pregnancy loss in women with pregnancy loss., PMID:39940054

In vitro combined haemostatic efficacy of emicizumab and extended half-life factor VIII compounds., PMID:39937791

The generation and evaluation of TKO/hCD55/hTM/hEPCR gene-modified pigs for clinical organ xenotransplantation., PMID:39902050

2025 Clinical Trials Update on Hemophilia, VWD, and Rare Inherited Bleeding Disorders., PMID:39901862

Coagulation Profile of Convalescent Plasma Donors and Recipients., PMID:39886886

Biomechanical and Functional Features of the Carrier Erythrocytes Prolonging Circulation Time of Biotherapeutic Targeted to Glycophorin A., PMID:39869932

Protection of β2GPI-deficient mice from thrombosis reflects a defect in PAR3-facilitated platelet activation., PMID:39869832

Antibody ligation of HLA class II induces YAP nuclear localization and formation of cytoplasmic YAP condensates in human endothelial cells., PMID:39865973

No correlation between thrombin generation and emicizumab levels: implications for monitoring emicizumab therapy., PMID:39850577

Inflammation and Coagulation in Neurologic and Psychiatric Disorders., PMID:39848256

Structural Conformation and the Binding of Factor VIII R2159C (FVIII-Ise) Mutated in the C1 Domain to Phospholipid., PMID:39837555

Transcriptomic and functional characterization of megakaryocytic-derived platelet-like particles: impaired aggregation and prominent anti-tumor effects., PMID:39812346

Complex Pattern of Platelet Activation/Reactivity After SARS-CoV-2 Infection., PMID:39795908

Understanding the effects of Bothrops erythromelas and Bothrops leucurus venoms on human blood coagulation., PMID:39788325

Brolucizumab and Platelet Activation and Reactivity., PMID:39760267

Gold Nanoprism Enhanced SERS Aptasensor for Simultaneous Detection of Thrombin and VEGF., PMID:39744119

Impaired coagulation parameters in early RA are restored by effective antirheumatic therapy: a prospective pilot study., PMID:39740931

HINODE study: haemophilia A in infancy and newborns - protocol for a prospective, multicentre, observational study evaluating the coagulation potential and safety of emicizumab prophylaxis., PMID:39725422

Ex vivo evaluation of the effect of plasma-derived factor VIII/von Willebrand factor in patients with severe hemophilia A on emicizumab prophylaxis., PMID:39708197

Deficiency of neutrophil gelatinase-associated lipocalin elicits a hemophilia-like bleeding and clotting disorder in mice., PMID:39693621

Troubleshooting heparin resistance., PMID:39643992

Cross-reactivity of antigenic binding sites of antiphosphatidylserine/prothrombin antibodies in patients with pregnancy loss and epidermal growth factor., PMID:39631139

Non-factor Therapies for Hemophilia: Achievements and Perspectives., PMID:39613145

Recurrent Early Pregnancy Loss and Congenital Thrombophilia: A Prospective Study., PMID:39598015

Datasheet
$ 372
Product specifications
100 μg 372 1 mg 1486

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For research use only. Not for human or drug use.

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InVivoMAb Anti-Human thrombin Antibody (Iv0119) [VHB87401]
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