Catalog No.
VHB88001
Species reactivity
Human
Host species
Human
Isotype
IgG1, kappa
Clonality
Monoclonal
Target
PFD, Adipsin, C3 convertase activator, Complement factor D, CFD, DF, Properdin factor D
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P00746
Applications
ELISA, FCM, Neutralization
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
Iv0118
Rheology of CHO Cell Suspensions and Its Effects on High-Density Cultivation Process and Bioreactor Design., PMID:40100242
Computational Evaluation of Improved HIPEC Drug Delivery Kinetics via Bevacizumab-Induced Vascular Normalization., PMID:40006522
Glomerular injury induced by vinyl carbamate in A/J inbred mice: a novel model of membranoproliferative glomerulonephritis., PMID:39309006
MOF-Modified Microrollers for Bioimaging and Sustained Antibiotic Delivery., PMID:39196769
Subcutaneous vs intravenous abatacept in rheumatoid arthritis-interstitial lung disease. National multicentre study of 397 patients., PMID:39067148
Short-term cultured tumor fragments to study immunotherapy combinations based on CD137 (4-1BB) agonism., PMID:38988823
Nirsevimab and Hospitalization for RSV Bronchiolitis., PMID:38986058
Modeling scalability of impurity precipitation in downstream biomanufacturing., PMID:38539261
Safety and Immunogenicity of a Messenger RNA-Based Cytomegalovirus Vaccine in Healthy Adults: Results From a Phase 1 Randomized Clinical Trial., PMID:38478705
Folate Receptor Alpha Autoantibodies in the Pediatric Acute-Onset Neuropsychiatric Syndrome (PANS) and Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections (PANDAS) Population., PMID:38392599
[Comparative characteristics of the complement system in patients with C3-glomerulopathy and atypical hemolytic uremic syndrome of chronic course who suffered an acute episode of thrombotic microangiopathy]., PMID:38158966
[Epstein-Barr virus (Herpesviridae: Lymphocryptovirus) types 1 and 2 and other viral markers in patients with nasopharyngeal carcinoma in two geographically and ethnically distinct regions of Russia]., PMID:38156586
Microwave-Assisted Freeze-Drying: Impact of Microwave Radiation on the Quality of High-Concentration Antibody Formulations., PMID:38140123
Complement factor D targeting protects endotheliopathy in organoid and monkey models of COVID-19., PMID:37802037
Abatacept in usual and in non-specific interstitial pneumonia associated with rheumatoid arthritis., PMID:37673775
Application of virtual product design to the development of HVAC solution for Incheon International Airport Modular COVID-19 testing center., PMID:37520923
Performance Optimization of a Microfluidic Virus Detection Cartridge: A Numerical and Experimental Study., PMID:37382621
Corrigendum: Kinetic studies and CFD-based reaction modeling for insights into the scalability of ADC conjugation reactions., PMID:37362209
Multiphysics Simulation of Local Transport and Absorption Coupled with Pharmacokinetic Modeling of Systemic Exposure of Subcutaneously Injected Drug Solution., PMID:37344601
Accelerated Production of Biopharmaceuticals via Microwave-Assisted Freeze-Drying (MFD)., PMID:37242584
Alternative Complement Pathway Inhibition by Lampalizumab: Analysis of Data From Chroma and Spectri Phase III Clinical Trials., PMID:37228694
Strong CD4+ T-Cell Responses to Ancestral and Variant Spike Proteins Are Established by NVX-CoV2373 Severe Acute Respiratory Syndrome Coronavirus 2 Primary Vaccination., PMID:37210741
Kinetic studies and CFD-based reaction modeling for insights into the scalability of ADC conjugation reactions., PMID:37082211
Identification of Embryonic Chicken Proteases Activating Newcastle Disease Virus and Their Roles in the Pathogenicity of Virus Used as In Ovo Vaccine., PMID:37042750
Brain Uptake of Folate Forms in the Presence of Folate Receptor Alpha Antibodies in Young Rats: Folate and Antibody Distribution., PMID:36904166
Experimental and computational characterization of mass transfer in high turndown bioreactors., PMID:36751946
Design of a microfluidic mixer channel: First steps into creating a fluorescent dye-based biosensor for mAb aggregate detection., PMID:36330557
Computational prediction of blend time in a large-scale viral inactivation process for monoclonal antibodies biomanufacturing., PMID:36224707
Computational fluid dynamic simulations of temperature, cryoconcentration, and stress time during large-scale freezing and thawing of monoclonal antibody solutions., PMID:35764219
In Vitro Study of Endothelial Cell Morphology and Gene Expression in Response to Wall Shear Stress Induced by Arterial Stenosis., PMID:35497360
Scale-up issues for commercial depth filters in bioprocessing., PMID:35032027
Blockade of the Terminal Complement Cascade Using Ravulizumab in a Pediatric Patient With Anti-complement Factor H Autoantibody-Associated aHUS: A Case Report and Literature Review., PMID:34912617
Complement Factor D as a Strategic Target for Regulating the Alternative Complement Pathway., PMID:34566967
Folate Receptor Alpha Autoantibodies in Autism Spectrum Disorders: Diagnosis, Treatment and Prevention., PMID:34442354
Complement factor D haplodeficiency is associated with a reduced complement activation speed and diminished bacterial killing., PMID:33841879
Serologic Testing of US Blood Donations to Identify Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)-Reactive Antibodies: December 2019-January 2020., PMID:33252659
Numerical framework for simulating bio-species transport in microfluidic channels with application to antibody biosensors., PMID:33251124
Comparison of overexpansion capabilities and thrombogenicity at the side branch ostia after implantation of four different drug eluting stents., PMID:33247219
International Myeloma Working Group risk stratification model for smoldering multiple myeloma (SMM)., PMID:33067414
A z2 laterally-fed membrane chromatography device for fast high-resolution purification of biopharmaceuticals., PMID:32861093
A CFD model for predicting protein aggregation in low-pH virial inactivation for mAb production., PMID:32672835
Identification and validation of differential plasma proteins levels in epithelial ovarian cancer., PMID:32634479
Weekly paclitaxel plus bevacizumab versus docetaxel as second- or third-line treatment in advanced non-squamous non-small-cell lung cancer: Results of the IFCT-1103 ULTIMATE study., PMID:32276179
Simulation of continuous low pH viral inactivation inside a coiled flow inverter., PMID:31868222
Microwave-Assisted Freeze-Drying of Monoclonal Antibodies: Product Quality Aspects and Storage Stability., PMID:31842296
Low volume aseptic filling: Impact of pump systems on shear stress., PMID:31837391
Simulation of pH level distribution inside a coiled flow inverter for continuous low pH viral inactivation., PMID:31631326
Discovery and Development of the Oral Complement Factor D Inhibitor Danicopan (ACH-4471)., PMID:31573880
Mixing of a mAb Formulation in a New Magnetically Coupled Single-Use Mixing System: Key Learnings of Preliminary Experimental and Computational Evaluation., PMID:31521644
Serum proteomics analysis based on label-free revealed the protective effect of Chinese herbal formula Gu-Ben-Fang-Xiao., PMID:31520916
For research use only. Not for human or drug use.
