Catalog No.
DHJ42802
Expression system
Mammalian Cells
Species reactivity
Human
Host species
Human
Isotype
Fusion - ALB (albumin, human serum albumin, HSA) 25-609 - CSF3 (colony stimulating factor 3, GCSF, granulocyte colony-stimulating factor, G-CSF)
Target
G-CSF receptor, CSF3R, GCSFR, G-CSF-R, CD114, Granulocyte colony-stimulating factor receptor
Concentration
0.5 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Purified by Ion Exchange Chromatography.
Accession
Q99062
Applications
Research Grade Biosimilar
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names
ALB-rG-CSF, G-CSF-HAS, HSA-rG-CSF, EGRANLI™, NEUGRANIN™, ALBUGRANIN™
Clone ID
Balugrastim
Advances in the pharmacological management of neutropenia in solid tumors: the advent of biosimilars., PMID:33579166
Efficacy and tolerability of granulocyte colony-stimulating factors in cancer patients after chemotherapy: A systematic review and Bayesian network meta-analysis., PMID:31653961
New developments in the treatment of chemotherapy-induced neutropenia: focus on balugrastim., PMID:27445479
A Phase III Study of Balugrastim Versus Pegfilgrastim in Breast Cancer Patients Receiving Chemotherapy With Doxorubicin and Docetaxel., PMID:26668251
Phase II dose-finding study of balugrastim in breast cancer patients receiving myelosuppressive chemotherapy., PMID:25966791
First-in-human, phase I/IIa dose-escalation and safety study of balugrastim in breast cancer patients receiving myelosuppressive chemotherapy., PMID:25740691
Recombinant human serum albumin fusion proteins and novel applications in drug delivery and therapy., PMID:25732550
Efficacy, effectiveness and safety of long-acting granulocyte colony-stimulating factors for prophylaxis of chemotherapy-induced neutropenia in patients with cancer: a systematic review., PMID:25284721
Efficacy and safety of balugrastim compared with pegfilgrastim in patients with breast cancer receiving chemotherapy., PMID:24485296