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Research Grade Balugrastim

Catalog #:   DHJ42802 Specific References (9) DATASHEET
Host species: Human
Isotype: Fusion - ALB (albumin, human serum albumin, HSA) 25-609 - CSF3 (colony stimulating factor 3, GCSF, granulocyte colony-stimulating factor, G-CSF)
Applications: Research Grade Biosimilar
Expression system: Mammalian Cells
Overview

Catalog No.

DHJ42802

Expression system

Mammalian Cells

Species reactivity

Human

Host species

Human

Isotype

Fusion - ALB (albumin, human serum albumin, HSA) 25-609 - CSF3 (colony stimulating factor 3, GCSF, granulocyte colony-stimulating factor, G-CSF)

Target

G-CSF receptor, CSF3R, GCSFR, G-CSF-R, CD114, Granulocyte colony-stimulating factor receptor

Concentration

0.5 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Purified by Ion Exchange Chromatography.

Accession

Q99062

Applications

Research Grade Biosimilar

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Alternative Names

ALB-rG-CSF, G-CSF-HAS, HSA-rG-CSF, EGRANLI™, NEUGRANIN™, ALBUGRANIN™

Clone ID

Balugrastim

Data Image
References

Advances in the pharmacological management of neutropenia in solid tumors: the advent of biosimilars., PMID:33579166

Efficacy and tolerability of granulocyte colony-stimulating factors in cancer patients after chemotherapy: A systematic review and Bayesian network meta-analysis., PMID:31653961

New developments in the treatment of chemotherapy-induced neutropenia: focus on balugrastim., PMID:27445479

A Phase III Study of Balugrastim Versus Pegfilgrastim in Breast Cancer Patients Receiving Chemotherapy With Doxorubicin and Docetaxel., PMID:26668251

Phase II dose-finding study of balugrastim in breast cancer patients receiving myelosuppressive chemotherapy., PMID:25966791

First-in-human, phase I/IIa dose-escalation and safety study of balugrastim in breast cancer patients receiving myelosuppressive chemotherapy., PMID:25740691

Recombinant human serum albumin fusion proteins and novel applications in drug delivery and therapy., PMID:25732550

Efficacy, effectiveness and safety of long-acting granulocyte colony-stimulating factors for prophylaxis of chemotherapy-induced neutropenia in patients with cancer: a systematic review., PMID:25284721

Efficacy and safety of balugrastim compared with pegfilgrastim in patients with breast cancer receiving chemotherapy., PMID:24485296

Datasheet

Document Download

Research Grade Balugrastim.pdf

 

$ 426
Product specifications
100 μg 426 1 mg 1704

Contact Information

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Distributor list

For research use only. Not for human or drug use.

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Research Grade Balugrastim [DHJ42802]
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