Catalog No.
RHE20301
Species reactivity
Human, Mouse, Rat, Rabbit, Pig
Host species
Mouse
Isotype
IgG2a, kappa
Clonality
Monoclonal
Applications
DB, ELISA, IHC, IP, WB
Target
PHGPx, Glutathione peroxidase 4, GPX4, GSHPx-4, GPx-4, Phospholipid hydroperoxide glutathione peroxidase
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P36969
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
SAA0487
Note
For research use only.
Targeting ferroptosis: Paving new roads for drug design and discovery., PMID:36543035
Blocking EREG/GPX4 Sensitizes Head and Neck Cancer to Cetuximab through Ferroptosis Induction., PMID:36899869
B cell-derived anti-beta 2 glycoprotein I antibody mediates hyperhomocysteinemia-aggravated hypertensive glomerular lesions by triggering ferroptosis., PMID:36907919
Ferroptosis participates in dibutyl phthalate-aggravated allergic asthma in ovalbumin-sensitized mice., PMID:37018853
Trastuzumab-induced cardiomyopathy via ferroptosis-mediated mitochondrial dysfunction., PMID:37392951
Deubiquitinase inhibitor PR-619 potentiates colon cancer immunotherapy by inducing ferroptosis., PMID:37526037
Identification of Diagnosis and Typological Characteristics Associated with Ferroptosis for Ulcerative Colitis via Bioinformatics and Machine Learning., PMID:37957905
Influence of ferroptosis indicators on the stability of atherosclerotic plaque., PMID:38158665
STING upregulation mediates ferroptosis and inflammatory response in lupus nephritis by upregulating TBK1 and activating NF-κB signal pathway., PMID:38186000
The oxidized phospholipid PGPC impairs endothelial function by promoting endothelial cell ferroptosis via FABP3., PMID:38218337
Anti-NOTCH1 therapy with OMP-52 M51 inhibits salivary adenoid cystic carcinoma by depressing epithelial-mesenchymal transition (EMT) process and inducing ferroptosis., PMID:38253083
A pH-responsive cetuximab-conjugated DMAKO-20 nano-delivery system for overcoming K-ras mutations and drug resistance in colorectal carcinoma., PMID:38331131
Prevention of bleomycin-induced pulmonary fibrosis by vaccination with the Tocilizumab mimotope., PMID:38408907
Targeting FTO induces colorectal cancer ferroptotic cell death by decreasing SLC7A11/GPX4 expression., PMID:38600610
Correction: Targeting FTO induces colorectal cancer ferroptotic cell death by decreasing SLC7A11/ GPX4 expression., PMID:38693552
ANO6 (TMEM16F) inhibits gastrointestinal stromal tumor growth and induces ferroptosis., PMID:38756246
Inhibition of ER stress using tauroursodeoxycholic acid rescues obesity-evoked cardiac remodeling and contractile anomalies through regulation of ferroptosis., PMID:38906502
Genetically Engineered Membrane-Coated Nanoparticles for Enhanced Prostate-Specific Membrane Antigen Targeting and Ferroptosis Treatment of Castration-Resistant Prostate Cancer., PMID:38946578
Inhibition of ferroptosis rescues M2 macrophages and alleviates arthritis by suppressing the HMGB1/TLR4/STAT3 axis in M1 macrophages., PMID:39029270
Licochalcone A mitigates aflatoxin B1-induced immunotoxicity via ferroptosis in bursa of broilers and macrophages., PMID:39106705
4-Hydroxychalcone attenuates ovalbumin-induced allergic airway inflammation and oxidative stress by activating Nrf2/GPx4 pathway., PMID:39260757
Glutathione-Disrupting Nanotherapeutics Potentiate Ferroptosis for Treating Luminal Androgen Receptor-Positive Triple-Negative Breast Cancer., PMID:39287044
β-glucan nanoparticles alleviate acute asthma by suppressing ferroptosis and DNA damage in mice., PMID:39305381
Integrative microbiomics, proteomics and lipidomics studies unraveled the preventive mechanism of Shouhui Tongbian Capsules on cerebral ischemic stroke injury., PMID:39362332
Immunohistochemical examination of immunoreactivity of transient receptor potential melastatin 2, glutathione peroxidase 4 and spexin in lichen planus., PMID:39400728
Chemokine CXCL13 facilitates anti-FVIII inhibitory antibody development in hemophilia A patients and murine models., PMID:39471695
Rituximab induces ferroptosis and RSL3 overcomes rituximab resistance in diffuse large B-cell lymphoma cells., PMID:39490616
Advances in the study of artemisinin and its derivatives for the treatment of rheumatic skeletal disorders, autoimmune inflammatory diseases, and autoimmune disorders: a comprehensive review., PMID:39524446
Sorafenib-induced macrophage extracellular traps via ARHGDIG/IL4/PADI4 axis confer drug resistance through inhibiting ferroptosis in hepatocellular carcinoma., PMID:39529192
SHR-1806, a robust OX40 agonist to promote T cell-mediated antitumor immunity., PMID:39543823
Self-catalyzed nitric oxide nanocomplexes induce ferroptosis for cancer immunotherapy., PMID:39580079
Lenvatinib-activated NDUFA4L2/IL33/PADI4 pathway induces neutrophil extracellular traps that inhibit cuproptosis in hepatocellular carcinoma., PMID:39585643
HMGA1 influence on iron-induced cell death in Tfh cells of SLE patients., PMID:39707065
Enhancing Ferroptosis-Mediated Radiosensitization via Synergistic Disulfidptosis Induction., PMID:39727204
Deciphering the role of TMEM164 in autophagy-mediated ferroptosis and immune modulation in non-small cell lung cancer., PMID:39798196
Effect of the glucagon-like peptide-1 receptor agonists dulaglutide on kidney outcomes in db/db mice., PMID:39805329
T-2 toxin triggers immunotoxic effects in goats by inducing ferroptosis and neutrophil extracellular traps., PMID:39832565
The roles of IDH2 and glutathione metabolism in cetuximab resistance in head and neck squamous cell carcinoma investigated by metabolomics and transcriptomics., PMID:39842530
A pH-responsive PROTAC-based nanosystem triggers tumor-specific ferroptosis to construct in situ tumor vaccines., PMID:39935894
Dulaglutide accelerates diabetic wound healing by suppressing Nrf2-dependent ferroptosis in diabetic mice., PMID:39954860
Gancao Xiexin decoction attenuated experimental colitis through suppressing ACSL4-mediated ferroptosis., PMID:39993549
Hsa_circ_0002301 inhibits ferroptosis in gastric cancer by encoding the de novo protein HECTD1-463aa., PMID:40022084
Resveratrol alleviates testicular toxicity induced by anti-PD-1 through regulating the NRF2-SLC7A11-GPX4 pathway., PMID:40145083
4-1BB stimulation with concomitant inactivation of adenosine A2B receptors enhances CD8+ T cell antitumor response., PMID:40178905
Transcription factor KLF5 regulates MsrB1 to promote colorectal cancer progression by inhibiting ferroptosis through β-catenin., PMID:40210135
Sodium butyrate increases USP5-mediated ubiquitination degradation of GPX4 and enhances anti-cancer efficacy of anti-PD-1 antibody., PMID:40216263
Upregulation of ferroptosis in glucocorticoids-induced posterior subcapsular cataracts., PMID:40234585
PSAT1 impairs ferroptosis and reduces immunotherapy efficacy via GPX4 hydroxylation., PMID:40281343
Nano co-inducer of immunogenic cell death and ferroptosis for anti-tumor immunotherapy., PMID:40424799
Targeting IL-33 to Suppress Ferroptosis and Alleviate Inflammation in Asthma Exacerbations., PMID:40499633
For research use only. Not for human or drug use.
