Anti-Human TSLP Antibody (SAA0472)

Catalog No.

FHJ36110

Species reactivity

Human

Host species

Human

Isotype

IgG1, kappa

Clonality

Monoclonal

Conjugation

Unconjugated

Target

TSLP, Thymic stromal lymphopoietin

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q969D9

Applications

ELISA, FCM

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.09% Sodium azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

SAA0472

Baseline type 2 biomarker levels and clinical remission predictors in children with asthma., PMID:40503233

Polynucleotides Enhance Skin Barrier Function and Reduce Inflammation in a 2,4-Dinitrochlorobenzene-Induced Mouse Model of Atopic Dermatitis., PMID:40484710

Real-life preliminary evidence for Basophils as predictors of tezepelumab response in severe asthma., PMID:40471866

How to adjust asthma management once asthma is controlled on long term biologic therapy., PMID:40436142

Anti-Inflammatory Effects of Polyglycerol Sulfates and Natural Polyanions in Type 2 Inflammation., PMID:40408775

Preclinical Development of GR2002, a Novel Anti-TSLP Bispecific Antibody With Potent TSLP Inhibitory Effects., PMID:40372096

T2 cytokine-driven alarmin and antiviral responses in asthma: insights into immune modulation and the role of IL-4Rα targeting., PMID:40370530

Microneedles Coated with Cow's Milk Proteins: Immunogenicity, Stability, and Safety Assessment., PMID:40366634

Clinical and Biological Remission With Tezepelumab: The Real-World Response in Severe Uncontrolled Asthma., PMID:40365686

Biologic Therapies for Severe Asthma: Current Insights and Future Directions., PMID:40364184

Blocking of IL-4/IL-13 Signalling With Dupilumab Results in Restoration of Serum and Cutaneous Abnormalities in Netherton Syndrome., PMID:40344324

The clinical and pathological histology efficacy of biological therapy for severe asthma with a phenotype of type 2 inflammation - systematic review., PMID:40303400

New Therapeutic Challenges in Pediatric Gastroenterology: A Narrative Review., PMID:40281872

The impact of tezepelumab therapy on perceived asthma triggers: a multicenter real-life study., PMID:40257396

Sensitization Potential of the Major Soybean Allergen Gly m 4 and Its Cross-Reactivity with the Birch Pollen Allergen Bet v 1., PMID:40243572

TNF-α counters skin inflammation by restraining mast cell-dependent thymic stromal lymphopoietin production., PMID:40189158

Translational Investigation of CM326 from Preclinical Studies to Randomized Phase I Clinical Trials in Healthy Adults., PMID:40185989

IgE-Mediated Activation of Mast Cells and Basophils in Health and Disease., PMID:40165512

Head-To-Head Comparison of Biologic Efficacy in Asthma: What Have We Learned?, PMID:40156481

Ascorbic Acid Encapsulated in Apoferritin as Improved Protoporphyrin-Sensitized TiO2 Nanoarrays of a Photoelectrochemical Nanobody-Based Microfluidic Biosensor for Immunoassay., PMID:40082220

Ameliorative Effects of Escin on Inflammation via Glucocorticoid Receptor (GR) in Atopic Dermatitis (AD) Mouse Model., PMID:40081901

Maternal supplementation with α-tocopherol inhibits the development of offspring food allergy, H1R signaling and ultimately anaphylaxis early in life., PMID:40073242

Distinct roles for thymic stromal lymphopoietin (TSLP) and IL-33 in experimental eosinophilic esophagitis., PMID:40060399

Triclosan exacerbates atopic dermatitis in mouse models via thymic stromal lymphopoietin., PMID:40059030

Thymic stromal lymphopoietin improves protective immunity of the SARS-CoV-2 subunit vaccine by inducing dendritic cell-dependent germinal center response., PMID:40035515

Advances in Biologic Therapies for Allergic Diseases: Current Trends, Emerging Agents, and Future Perspectives., PMID:40004611

Dual Inhibition of Mast Cells and Thymic Stromal Lymphopoietin Using a Novel Bispecific Antibody, CDX-622., PMID:39976188

Tezepelumab for the treatment of chronic spontaneous urticaria: Results of the phase 2b INCEPTION study., PMID:39956278

A proof-of-mechanism trial in asthma with lunsekimig, a bispecific NANOBODY molecule., PMID:39884759

Emerging biological treatments for asthma., PMID:39873193

Targeting alarmins in asthma: From bench to clinic., PMID:39855362

[Mechanism of inflammatory microecological response to TAS2R14/SIgA/TSLP in regulating epithelial cell barrier in cold asthma rats through lung-gut axis by using Shegan Mahuang Decoction and bitter and purging Chinese herbs]., PMID:39805760

Fibroblast growth factor 21 alleviated atopic march by inhibiting the differentiation of type 2 helper T cells., PMID:39798471

TSLP acts on regulatory T cells to maintain their identity and limit allergic inflammation., PMID:39792638

A novel monoclonal antibody against human thymic stromal lymphopoietin for the treatment of TSLP-mediated diseases., PMID:39726595

Changing paradigms in asthma management., PMID:39709041

Thymic stromal lymphopoietin modulates T cell response and improves cardiac repair post-myocardial infarction., PMID:39703503

Anti-Atopic Dermatitis Effect of Azalomycin F on 2,4-Dinitrofluorobenzene-Induced Mice and Potential Mechanism., PMID:39684557

Interleukin-38-overexpressing adenovirus infection in dendritic cell-based treatment enhances immunotherapy for allergic asthma via inducing Foxp3+ regulatory T cells., PMID:39667222

Thymic Stromal Lymphopoietin (TSLP): Evidence in Respiratory Epithelial-driven Diseases Including Chronic Rhinosinusitis with Nasal Polyps., PMID:39636450

Biologics treatment for eosinophilic chronic rhinosinusitis complicated by bronchial asthma: Narrative review., PMID:39626320

Differences in the direct effects of various type 2 cytokines on functions of blood eosinophils from healthy subjects., PMID:39624446

Type 2 cytokine-JAK1 signaling is involved in the development of dry skin-induced mechanical alloknesis., PMID:39616021

Biologics in allergology and clinical immunology: Update on therapies for atopic diseases, urticaria, and angioedema and on safety aspects focusing on hypersensitivity reactions., PMID:39600395

Protective effect of Curcuma longa L. leaves and pseudostems extract against 1-chloro-2,4-dinitrobenzene-induced atopic dermatitis in BALB/c mice., PMID:39566860

House dust mites stimulate thymic stromal lymphopoietin production in human bronchial epithelial cells and promote airway remodeling through activation of PAR2 and ERK signaling pathway., PMID:39562597

Positioning tezepelumab for patients with severe asthma: from evidence to unmet needs., PMID:39552062

Four-month real-life response to Tezepelumab in patients with multi-failure to other biologics., PMID:39515799

MERS-CoV Infection and Its Impact on the Expression of TSLP Cytokine and IgG Antibodies: An In Vivo and In Vitro Study., PMID:39469096

Interferon as an immunoadjuvant to enhance antibodies following influenza B infection and vaccination in ferrets., PMID:39448628

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