Catalog No.
FHJ97810
Species reactivity
Human
Host species
Mouse
Isotype
IgG2a, kappa
Clonality
Monoclonal
Conjugation
Unconjugated
Target
IEGF, PDGFD latent form, PDGF-D, Spinal cord-derived growth factor B, SCDGF-B, Iris-expressed growth factor, PDGFD, Platelet-derived growth factor D, PDGFD receptor-binding form, SCDGFB
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q9GZP0
Applications
ELISA, FCM
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.09% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
SAA0451
PDGF-D Is Dispensable for the Development and Progression of Murine Alport Syndrome., PMID:38309427
Expression and prognostic significance of PDGF ligands and receptors across soft tissue sarcomas., PMID:33524869
Defining Endothelial Cell-Derived Factors That Promote Pericyte Recruitment and Capillary Network Assembly., PMID:32814441
Characterization of gene expression profiles in HBV-related liver fibrosis patients and identification of ITGBL1 as a key regulator of fibrogenesis., PMID:28262670
[Primary culture and characteristics of colorectal cancer-associated fibroblasts]., PMID:26702529
Naturally occurring PDGF receptor inhibitors with potential anti-atherosclerotic properties., PMID:25737405
Platelet-derived growth factor-D modulates extracellular matrix homeostasis and remodeling through TIMP-1 induction and attenuation of MMP-2 and MMP-9 gelatinase activities., PMID:25576870
Overexpression of platelet-derived growth factor-D as a poor prognosticator in endometrial cancer., PMID:24870786
Distinct effects of ligand-induced PDGFRα and PDGFRβ signaling in the human rhabdomyosarcoma tumor cell and stroma cell compartments., PMID:23338608
Growth arrest-specific protein 1 is a novel endogenous inhibitor of glomerular cell activation and proliferation., PMID:23254899
Platelet-derived growth factor (PDGF)-C neutralization reveals differential roles of PDGF receptors in liver and kidney fibrosis., PMID:23141925
Orbit-infiltrating mast cells, monocytes, and macrophages produce PDGF isoforms that orchestrate orbital fibroblast activation in Graves' ophthalmopathy., PMID:22238384
Epithelial-mesenchymal transition in breast cancer lines is mediated through PDGF-D released by tissue-resident stem cells., PMID:22038895
[Expressions of receptor tyrosine kinases mRNA and protein in carcinoma of bladder]., PMID:21906447
PDGF-D improves drug delivery and efficacy via vascular normalization, but promotes lymphatic metastasis by activating CXCR4 in breast cancer., PMID:21459800
Patients with IgA nephropathy exhibit high systemic PDGF-DD levels., PMID:19357108
A phase I study of CR002, a fully-human monoclonal antibody against platelet-derived growth factor-D., PMID:18538109
Angiotensin II-inducible platelet-derived growth factor-D transcription requires specific Ser/Thr residues in the second zinc finger region of Sp1., PMID:18258854
Identification of platelet-derived growth factor D in human chronic allograft nephropathy., PMID:18187181
Down-regulation of platelet-derived growth factor-D inhibits cell growth and angiogenesis through inactivation of Notch-1 and nuclear factor-kappaB signaling., PMID:18056465
PDGF-C and -D induced proliferation/migration of human RPE is abolished by inflammatory cytokines., PMID:18055825
PDGF-D inhibition by CR002 ameliorates tubulointerstitial fibrosis following experimental glomerulonephritis., PMID:17308324
Antagonism of PDGF-D by human antibody CR002 prevents renal scarring in experimental glomerulonephritis., PMID:16510766
Platelet-derived growth factor D, tissue-specific expression in the eye, and a key role in control of lens epithelial cell proliferation., PMID:15611105
A fully human monoclonal antibody (CR002) identifies PDGF-D as a novel mediator of mesangioproliferative glomerulonephritis., PMID:12937299
Platelet-derived growth factor-D expression in developing and mature human kidneys., PMID:12427128
For research use only. Not for human or drug use.
