Catalog No.
FHB91210
Species reactivity
Human
Host species
Mouse
Isotype
IgG2a, kappa
Clonality
Monoclonal
Conjugation
Unconjugated
Target
PDGF-2, Proto-oncogene c-Sis, PDGF2, SIS, Platelet-derived growth factor B chain, PDGFB, Becaplermin, Platelet-derived growth factor beta polypeptide, Platelet-derived growth factor subunit B, PDGF subunit B
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P01127
Applications
ELISA, FCM
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.09% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
SAA0449
IL13RA2-integrated genetically engineered mouse model allows for CAR T cells targeting pediatric high-grade gliomas., PMID:40176156
IL13RA2-integrated genetically engineered mouse model allows for CAR T cells targeting pediatric high-grade gliomas., PMID:39711568
PCSK9 promotes vascular neointimal hyperplasia through non-lipid regulation of vascular smooth muscle cell proliferation, migration, and autophagy., PMID:39632291
Inflammatory crosstalk impairs phagocytic receptors and aggravates atherosclerosis in clonal hematopoiesis in mice., PMID:39531316
Targeting TREM2 signaling shows limited impact on cerebrovascular calcification., PMID:39467636
Blocking IL-33 decelerates cartilage degeneration in knee osteoarthritis through mice model., PMID:39172956
One-Pot Detection of Proteins Using a Two-Way Extension-Based Assay with Cas12a., PMID:39078660
HnRNPA1 Prevents Endothelial-to-mesenchymal Transition-induced VSMC Activation and Neointimal Hyperplasia in Vein Grafts., PMID:39046653
Differential responses to thrombospondin-1 and PDGF-BB in smooth muscle cells from atherosclerotic coronary arteries and internal thoracic arteries., PMID:38982274
Triblock PolyA-Mediated Protein Biosensor Based on a Size-Matching Proximity Hybridization Analysis., PMID:38632948
Effects of aflibercept and bevacizumab on cell viability, cell metabolism and inflammation in hypoxic human Müller cells., PMID:38536827
Echinacoside ameliorates hepatic fibrosis and tumor invasion in rats with thioacetamide-induced hepatocellular carcinoma., PMID:38461536
Tumor-mesothelium HOXA11-PDGF BB/TGF β1-miR-181a-5p-Egr1 feedforward amplifier circuity propels mesothelial fibrosis and peritoneal metastasis of gastric cancer., PMID:37989866
Hepatocyte CYR61 polarizes profibrotic macrophages to orchestrate NASH fibrosis., PMID:37756381
Magnetic Resonance Imaging of Mouse Cerebral Cavernomas Reveal Differential Lesion Progression and Variable Permeability to Gadolinium., PMID:37078284
The effect of cilostazol on the platelet-derived growth factor-beta/beta isoform reduction on venous hyperplasia in an experimental balloon-induced injury model., PMID:36911886
An angiogenic tumor phenotype predicts poor prognosis in ovarian cancer., PMID:36758419
The role of tribbles homolog 2 in vascular smooth muscle cell proliferation., PMID:36626273
PDGF-BB prevents destructive repair and promotes reparative osteogenesis of steroid-associated osteonecrosis of the femoral head in rabbits., PMID:36539110
The Role of Platelet-Derived Growth Factor in Focal Segmental Glomerulosclerosis., PMID:36351762
β1 integrin monoclonal antibody treatment ameliorates cerebral cavernous malformations., PMID:36349990
Cytokines/chemokines and soluble immune checkpoint molecules in anti-GABAB receptor encephalitis., PMID:36270252
Pro-Inflammatory Profile of Children Exposed to Maternal Chikungunya Virus Infection during the Intrauterine Period: A One-Year Follow-Up Study., PMID:36146688
Distinct Immune Phenotypes and Cytokine Profiles in Children with Differing Severity of COVID-19., PMID:36102684
SB431542 alleviates lupus nephritis by regulating B cells and inhibiting the TLR9/TGFβ1/PDGFB signaling., PMID:36030617
Cardiomyocytes induced from hiPSCs by well-defined compounds have therapeutic potential in heart failure by secreting PDGF-BB., PMID:35902567
Total flavonoids of Rhizoma Drynariae enhances CD31hiEmcnhi vessel formation and subsequent bone regeneration in rat models of distraction osteogenesis by activating PDGF‑BB/VEGF/RUNX2/OSX signaling axis., PMID:35795995
Chemiluminescent detection of platelet derived growth factor-BB based on sandwich label-free aptasensor and biotin-streptavidin strategy., PMID:35644254
Tubular cells produce FGF2 via autophagy after acute kidney injury leading to fibroblast activation and renal fibrosis., PMID:35491858
Autologous hematopoietic stem cell transplantation promotes connective tissue remodeling in systemic sclerosis patients., PMID:35488348
Cabozantinib with or without Panitumumab for RAS wild-type metastatic colorectal cancer: impact of MET amplification on clinical outcomes and circulating biomarkers., PMID:35171350
Mast Cells and Basophils in the Defense against Ectoparasites: Efficient Degradation of Parasite Anticoagulants by the Connective Tissue Mast Cell Chymases., PMID:34884431
Regulation of Transplanted Cell Homing by FGF1 and PDGFB after Doxorubicin Myocardial Injury., PMID:34831221
An antibody against Siglec-15 promotes bone formation and fracture healing by increasing TRAP+ mononuclear cells and PDGF-BB secretion., PMID:34719673
Endothelial cell-derived pro-fibrotic factors increase TGF-β1 expression by smooth muscle cells in response to cycles of hypoxia-hyperoxia., PMID:34601016
Urine Proteomics Differentiate Primary Thrombotic Antiphospholipid Syndrome From Obstetric Antiphospholipid Syndrome., PMID:34489952
A SERS-LFA biosensor combined with aptamer recognition for simultaneous detection of thrombin and PDGF-BB in prostate cancer plasma., PMID:34298537
Differential Cytokine Responses in Hospitalized COVID-19 Patients Limit Efficacy of Remdesivir., PMID:34262564
High-throughput sequencing defines donor and recipient HLA B-cell epitope frequencies for prospective matching in transplantation., PMID:33990681
Targeted mutagenesis on PDGFRα-Fc identifies amino acid modifications that allow efficient inhibition of HCMV infection while abolishing PDGF sequestration., PMID:33780515
Pericytes regulate vascular immune homeostasis in the CNS., PMID:33653955
Inhibition of PDGF-BB reduces alkali-induced corneal neovascularization in mice., PMID:33537811
Expression and prognostic significance of PDGF ligands and receptors across soft tissue sarcomas., PMID:33524869
DutaFabs are engineered therapeutic Fab fragments that can bind two targets simultaneously., PMID:33514724
Effect of PDGF-B Gene-Activated Acellular Matrix and Mesenchymal Stem Cell Transplantation on Full Thickness Skin Burn Wound in Rat Model., PMID:33145744
Neutralization of S100A4 induces stabilization of atherosclerotic plaques: role of smooth muscle cells., PMID:33135065
Knockout of EGFL6 by CRISPR/Cas9 Mediated Inhibition of Tumor Angiogenesis in Ovarian Cancer., PMID:32983976
Defining Endothelial Cell-Derived Factors That Promote Pericyte Recruitment and Capillary Network Assembly., PMID:32814441
Plasmid DNA gene therapy of the Niemann-Pick C1 mouse with transferrin receptor-targeted Trojan horse liposomes., PMID:32770132
Clinical Management and Therapeutic Strategies for the Thyroid-Associated Ophthalmopathy: Current and Future Perspectives., PMID:32567373
For research use only. Not for human or drug use.
