Catalog No.
PHB90101
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human TIMP1 (Cys24-Ala207).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, IF:1:50-1:100, WB: 1:500-1:4000
Target
Erythroid-potentiating activity,TIMP,EPA,TIMP1,Metalloproteinase inhibitor 1,TIMP-1,Fibroblast collagenase inhibitor,Collagenase inhibitor,CLGI,Tissue inhibitor of metalloproteinases 1
Concentration
0.67 mg/ml
Purification
Purified by antigen affinity column.
Accession
P01033
Applications
ELISA, IHC, IF, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Proteomics uncovers ICAM2 (CD102) as a novel serum biomarker of proliferative lupus nephritis., PMID:40274316
Lung-delivered IL-10 mitigates Lung inflammation induced by repeated endotoxin exposures in male mice., PMID:39980189
Cold and hot fibrosis define clinically distinct cardiac pathologies., PMID:39970910
Human hypofunctional NCF1 variants promote pulmonary fibrosis in the bleomycin-induced mouse model and patients with systemic sclerosis via expansion of SPP1+ monocytes-derived macrophages., PMID:39919902
The effect of tocilizumab treatment for skin fibrosis by inhibiting CD38+ macrophages in systemic sclerosis., PMID:39778381
Exosomes derived from TREM-2 knocked-out macrophages alleviated renal fibrosis via HSPa1b/AKT pathway., PMID:39657110
An anti-RAGE chimeric antibody alleviates CCl4-induced liver fibrosis via RAGE/NF-kB pathway in mice., PMID:39657505
Low Iron Diet Improves Clinical Arthritis in the Mouse Model of Collagen-Induced Arthritis., PMID:39513899
Inhibition of Bruton's tyrosine kinase with PD-1 blockade modulates T cell activation in solid tumors., PMID:39513363
TIMP1 Mediates Astrocyte-Dependent Local Immunosuppression in Brain Metastasis Acting on Infiltrating CD8+ T Cells., PMID:39354883
Risk stratification analysis of recurrent myocardial infarction in Indian population using inflammatory, lipid, thrombotic and extracellular matrix remodeling markers., PMID:39351476
Evaluation of MMP-9, MMP-13, MMP-21, and TIMP-1 expressions in malign melanom, dysplastic nevi, and banal nevi., PMID:38757103
Host response during unresolved urinary tract infection alters female mammary tissue homeostasis through collagen deposition and TIMP1., PMID:38627380
A Complex Pattern of Gene Expression in Tissue Affected by Viperid Snake Envenoming: The Emerging Role of Autophagy-Related Genes., PMID:38540699
The Role of Matrix Metalloproteinases in Thoracic Aortic Disease: Are They Indicators for the Pathogenesis of Dissections?, PMID:38540232
An in vitro study elucidating the synergistic effects of aqueous cinnamon extract and an anti-TNF-α biotherapeutic: implications for a complementary and alternative therapy for non-responders., PMID:38521924
Prognostic and predictive analyses of circulating plasma biomarkers in men with metastatic castration resistant prostate cancer treated with docetaxel/prednisone with or without bevacizumab., PMID:38347114
Elevated matrix Metalloproteinase-9 associated with reduced cerebellar perineuronal nets in female mice with toxoplasmosis., PMID:38323226
Effects of different amosite preparations on macrophages, lung damages, and autoimmunity., PMID:38015242
Modulating asthma-COPD overlap responses with IL-17 inhibition., PMID:37965351
IgE Immune Complexes Mitigate Eosinophilic Immune Responses through NLRC4 Inflammasome., PMID:37885469
Correlations between different protein species of oral rinse MMP-8 and patient-related factors., PMID:37877535
Regulatory T-cell deficiency leads to features of autoimmune liver disease overlap syndrome in scurfy mice., PMID:37818371
Cytokine status and significant increase of IL-6 and sIL-6R in the aqueous humor of diabetic cataract patients revealed by quantitative multiplexed assays., PMID:37694725
Exploiting frequent and specific expression of PRL3 in pediatric solid tumors for first-in-child use of PRL3-zumab humanized antibody., PMID:37674627
Amyloid-β (Aβ) immunotherapy induced microhemorrhages are associated with activated perivascular macrophages and peripheral monocyte recruitment in Alzheimer's disease mice., PMID:37649100
Ursolic Acid Ameliorated Neuronal Damage by Restoring Microglia-Activated MMP/TIMP Imbalance in vitro., PMID:37637267
Proteomics Identifies Circulating TIMP-1 as a Prognostic Biomarker for Diffuse Large B-Cell Lymphoma., PMID:37500057
Analysis of N-glycosylation protein of Kashin-Beck disease chondrocytes derived from induced pluripotent stem cells based on label-free strategies with LC-MS/MS., PMID:37186116
Intrathecal administration of conditioned serum from different species resolves Chemotherapy-Induced neuropathic pain in mice via secretory exosomes., PMID:37150265
Cytokinopathy with aberrant cytotoxic lymphocytes and profibrotic myeloid response in SARS-CoV-2 mRNA vaccine-associated myocarditis., PMID:37146127
Kechuanning Gel Plaster Exerts Anti-inflammatory and Immunomodulatory Effects on Ovalbumin-induced Asthma Model Rats via ERK Pathway., PMID:37138476
Impairment of aryl hydrocarbon receptor signalling promotes hepatic disorders in cancer cachexia., PMID:37127348
Tissue Inhibitor of Metalloproteinase-1 Enhances Eosinophilic Airway Inflammation in Severe Asthma., PMID:37075799
Skeletonema marinoi Extracts and Associated Carotenoid Fucoxanthin Downregulate Pro-Angiogenic Mediators on Prostate Cancer and Endothelial Cells., PMID:37048126
Desmoglein-Specific B-Cell-Targeted Single-Cell Analysis Revealing Unique Gene Regulation in Patients with Pemphigus., PMID:36997112
Baicalin Inhibits Airway Smooth Muscle Cells Proliferation through the RAS Signaling Pathway in Murine Asthmatic Airway Remodeling Model., PMID:36814956
Myeloma Microenvironmental TIMP1 Induces the Invasive Phenotype in Fibroblasts to Modulate Disease Progression., PMID:36768545
Antitumor Effects of Deep Ultraviolet Irradiation for Pancreatic Cancer., PMID:36697074
Correlation between serum cytokines and clinicopathological features in patients with drug-induced liver injury., PMID:36569295
Role of Matrix Metalloproteinases and Their Inhibitors in Locally Invasive Papillary Thyroid Cancer., PMID:36551933
Among biomarkers of neutrophil activity, matrix metalloproteinases 8 independently predicts remission of metabolic syndrome., PMID:36411219
Metalloproteinases and Tissue Inhibitors in Generalized Myasthenia Gravis. A Preliminary Study., PMID:36358365
Five hub genes contributing to the oncogenesis and trastuzumab-resistance in gastric cancer., PMID:36202277
A transcriptomic map of EGFR-induced epithelial-to-mesenchymal transition identifies prognostic and therapeutic targets for head and neck cancer., PMID:36076232
Soluble markers of B cell activation suggest a role of B cells in the pathogenesis of systemic sclerosis-associated pulmonary arterial hypertension., PMID:35967377
Double-Negative T Cells Attenuate Cisplatin-Induced Acute Kidney Injury via Upregulating IL-10/AT2R Axis., PMID:35941899
Lack of autoantibodies against collagen and related proteins in collagenous colitis., PMID:35668375
Autologous hematopoietic stem cell transplantation promotes connective tissue remodeling in systemic sclerosis patients., PMID:35488348
Huangbai liniment and berberine promoted wound healing in high-fat diet/Streptozotocin-induced diabetic rats., PMID:35430394
For research use only. Not for human or drug use.
