InVivoMAb Anti-Human OSM/Oncostatin-M (Iv0092)

Catalog No.

VHD00501

Species reactivity

Human

Host species

Human

Isotype

IgG1, kappa

Clonality

Monoclonal

Target

Oncostatin-M, OSM

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P13725

Applications

ELISA, Neutralization

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

Iv0092

Oncostatin-M: a novel leukocyte-derived factor facilitating the ovulatory process in the human ovary., PMID:40327872

M2 Macrophage-Derived Extracellular Vesicles Reprogram Immature Neutrophils into Anxa1hi Neutrophils to Enhance Inflamed Bone Regeneration., PMID:40277454

A functional cardiac patch with "gas and ion" dual-effect intervention for reconstructing blood microcirculation in myocardial infarction repair., PMID:40174299

Novel cell-to-cell communications between macrophages and fibroblasts regulate obesity-induced adipose tissue fibrosis., PMID:40063503

Human oncostatin M deficiency underlies an inherited severe bone marrow failure syndrome., PMID:39847438

β-Catenin mediated TAM phenotype promotes pancreatic cancer metastasis via the OSM/STAT3/LOXL2 axis., PMID:39740539

Tumor-associated macrophages contribute to cholangiocarcinoma progression and chemoresistance through activation of ID1., PMID:39674368

Basal-to-inflammatory transition and tumor resistance via crosstalk with a pro-inflammatory stromal niche., PMID:39289380

Oncostatin M-driven macrophage-fibroblast circuits as a drug target in autoimmune arthritis., PMID:39080781

Glycinamide Facilitates Nanocomplex Formation and Functions Synergistically with Bone Morphogenetic Protein 2 to Promote Osteoblast Differentiation In Vitro and Bone Regeneration in a Mouse Calvarial Defect Model., PMID:38955905

Spleen derived monocytes regulate pulmonary vascular permeability in Hepatopulmonary syndrome through the OSM-FGF/FGFR1 signaling., PMID:38797433

Exercise Suppresses Head and Neck Squamous Cell Carcinoma Growth via Oncostatin M., PMID:38539521

IFNT-induced IRF1 enhances bovine endometrial receptivity by transactivating LIFR., PMID:38432052

Mitochondria targeted biomimetic platform for chemo/photodynamic combination therapy against osteosarcoma., PMID:38286195

Tumor-educated Gr1+CD11b+ cells drive breast cancer metastasis via OSM/IL-6/JAK-induced cancer cell plasticity., PMID:38236642

Oncostatin M Reduces Pathological Neovascularization in the Retina Through Müller Cell Activation., PMID:38190125

The LIFR Inhibitor EC359 Effectively Targets Type II Endometrial Cancer by Blocking LIF/LIFR Oncogenic Signaling., PMID:38139260

Oncostatin M Induces IFITM1 Expression to Inhibit Hepatitis B Virus Replication Via JAK-STAT Signaling., PMID:37879404

Peptides designed from a bacteriophage capsid protein function as synthetic transcription repressors., PMID:37865318

Raddeanin A Improves the Therapeutic Effect of Osimertinib in NSCLC by Accelerating ROS/NLRP3-mediated Pyroptosis., PMID:37861040

Oncostatin M/Oncostatin M Receptor Signal Induces Radiation-Induced Heart Fibrosis by Regulating SMAD4 in Fibroblast., PMID:37610394

Main active components of Ilex rotunda Thunb. protect against ulcerative colitis by restoring the intestinal mucosal barrier and modulating the cytokine-cytokine interaction pathways., PMID:37541404

Periradicular tissue fluid-derived biomarkers for apical periodontitis: An in vitro methodological and in vivo cross-sectional study., PMID:37464545

Targeting LncRNA LLNLR-299G3.1 with antisense oligonucleotide inhibits malignancy of esophageal squamous cell carcinoma cells in vitro and in vivo., PMID:37415734

MTMR3 risk alleles enhance Toll Like Receptor 9-induced IgA immunity in IgA nephropathy., PMID:37414396

Oncostatin M regulates macrophages polarization in osseointegration via yes-associated protein., PMID:37220694

OSMR deficiency aggravates pressure overload-induced cardiac hypertrophy by modulating macrophages and OSM/LIFR/STAT3 signalling., PMID:37120549

Carcinogen 4-Nitroquinoline Oxide (4-NQO) Induces Oncostatin-M (OSM) in Esophageal Cells., PMID:36881075

Type I Interferon Signaling is Required for Oncostatin-M Driven Inflammatory Responses in Mouse Lung., PMID:36346324

Oncostatin M: Risks and Benefits of a Novel Therapeutic Target for Atherosclerosis., PMID:35959619

Oncostatin M receptor regulates osteoblast differentiation via extracellular signal-regulated kinase/autophagy signaling., PMID:35765036

Extracellular Vesicles From TNFα Preconditioned MSCs: Effects on Immunomodulation and Bone Regeneration., PMID:35585987

Cells-Micropatterning Biomaterials for Immune Activation and Bone Regeneration., PMID:35478383

Macrophages direct cancer cells through a LOXL2-mediated metastatic cascade in pancreatic ductal adenocarcinoma., PMID:35428659

Stimulation of Osteoclast Formation by Oncostatin M and the Role of WNT16 as a Negative Feedback Regulator., PMID:35328707

The ILEI/LIFR complex induces EMT via the Akt and ERK pathways in renal interstitial fibrosis., PMID:35093095

Enhanced effect of recombinant adenoviruses co-expression of ING4 and OSM on anti-tumour activity of laryngeal cancer., PMID:35075768

Circ_0003159 upregulates LIFR expression through competitively binding to miR-221-3p/miR-222-3p to block gastric cancer development., PMID:35034206

Leukemia inhibitory factor-receptor signalling negatively regulates gonadotrophin-stimulated testosterone production in mouse Leydig Cells., PMID:35031431

Zn/Sr dual ions-collagen co-assembly hydroxyapatite enhances bone regeneration through procedural osteo-immunomodulation and osteogenesis., PMID:34901539

[Study on osteogenesis and angiogenesis of Pluronic F-127 composite gel loaded with transforming growth factor β 3 and bone marrow mesenchymal stem cells in rabbit maxillary sinus lift]., PMID:34779176

Macrophage-Mediated Bone Formation in Scaffolds Modified With MSC-Derived Extracellular Matrix Is Dependent on the Migration Inhibitory Factor Signaling Pathway., PMID:34621738

Diacerein Alone and in Combination with Infliximab Suppresses the Combined Proinflammatory Effects of IL-17A, IL-22, Oncostatin M, IL-1A, and TNF-alpha in Keratinocytes: A Potential Therapeutic Option in Psoriasis., PMID:34410877

Oncostatin M Receptor-Targeted Antibodies Suppress STAT3 Signaling and Inhibit Ovarian Cancer Growth., PMID:34380633

Retinal Protection by Sustained Nanoparticle Delivery of Oncostatin M and Ciliary Neurotrophic Factor Into Rodent Models of Retinal Degeneration., PMID:34347033

Long non-coding RNA Pvt1 modulates the pathological cardiac hypertrophy via miR-196b-mediated OSMR regulation., PMID:34245860

Oncostatin M promotes hepatic progenitor cell activation and hepatocarcinogenesis via macrophage-derived tumor necrosis factor-α., PMID:34102284

Interactions between cancer cells and immune cells drive transitions to mesenchymal-like states in glioblastoma., PMID:34087162

Lidocaine Suppresses Gastric Cancer Development Through Circ_ANO5/miR-21-5p/LIFR Axis., PMID:34050852

F4/80+ Kupffer Cell-Derived Oncostatin M Sustains the Progression Phase of Liver Regeneration through Inhibition of TGF-β2 Pathway., PMID:33924385

Document Download

InVivoMAb Anti-Human OSM/Oncostatin-M (Iv0092).pdf