Catalog No.
VHA04001
Species reactivity
Human
Host species
Human
Isotype
IgG1
Clonality
Monoclonal
Target
MPIF2, Eosinophil chemotactic protein 2, Small-inducible cytokine A24, CCL24, Eotaxin-2, SCYA24, MPIF-2, Myeloid progenitor inhibitory factor 2, CK-beta-6, C-C motif chemokine 24
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
O00175
Applications
ELISA, Neutralization
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
Iv0084
Risk signature of NETosis-related subtype predicts prognosis and evaluates immunotherapy effectiveness in gastric cancer., PMID:39525014
Downregulation of Salt-Inducible Kinase 3 Enhances CCL24 Activation in the Placental Environment with Preeclampsia., PMID:38203391
4,4'-Methylene diphenyl diisocyanate exposure induces expression of alternatively activated macrophage-associated markers and chemokines partially through Krüppel-like factor 4 mediated signaling in macrophages., PMID:38014489
Y-box binding protein 1 promotes chromatin accessibility to aggravate liver fibrosis., PMID:37290675
Type I Interferon Signaling is Required for Oncostatin-M Driven Inflammatory Responses in Mouse Lung., PMID:36346324
Allergic inflammation in lungs and nasal epithelium of rat model is regulated by tissue-specific miRNA expression., PMID:35537355
Hepatic recruitment of eosinophils and their protective function during acute liver injury., PMID:35259470
IL-33 reduces tumor growth in models of colorectal cancer with the help of eosinophils., PMID:32923137
Blocking the autocrine regulatory loop of Gankyrin/STAT3/CCL24/CCR3 impairs the progression and pazopanib resistance of clear cell renal cell carcinoma., PMID:32051393
Blockade of CCL24 with a monoclonal antibody ameliorates experimental dermal and pulmonary fibrosis., PMID:31129606
Extracellular vesicles derived from bone marrow mesenchymal stem cells attenuate dextran sodium sulfate-induced ulcerative colitis by promoting M2 macrophage polarization., PMID:31005036
Mesenchymal Stromal Cell (MSC)-Derived Combination of CXCL5 and Anti-CCL24 Is Synergistic and Superior to MSC and Cyclosporine for the Treatment of Graft-versus-Host Disease., PMID:29883796
Enhanced Pro-Inflammatory Response of Macrophages to Interleukin-33 in an Allergic Environment., PMID:29621782
The genes involved in asthma with the treatment of human embryonic stem cell-derived mesenchymal stem cells., PMID:29407576
Toll-Interacting Protein, Tollip, Inhibits IL-13-Mediated Pulmonary Eosinophilic Inflammation in Mice., PMID:29393212
Functional expression of CCL8 and its interaction with chemokine receptor CCR3., PMID:29281969
Lung Pathologies in a Chronic Inflammation Mouse Model Are Independent of Eosinophil Degranulation., PMID:27922744
IL-35 Suppresses Lipopolysaccharide-Induced Airway Eosinophilia in EBI3-Deficient Mice., PMID:27881708
Proton pump inhibitors decrease eotaxin-3/CCL26 expression in patients with chronic rhinosinusitis with nasal polyps: Possible role of the nongastric H,K-ATPase., PMID:27717558
Pre-administration of PepFect6-microRNA-146a nanocomplexes inhibits inflammatory responses in keratinocytes and in a mouse model of irritant contact dermatitis., PMID:27269729
Aquaporin-3 potentiates allergic airway inflammation in ovalbumin-induced murine asthma., PMID:27165276
TNF-related apoptosis-inducing ligand (TRAIL) regulates midline-1, thymic stromal lymphopoietin, inflammation, and remodeling in experimental eosinophilic esophagitis., PMID:25981737
CCL20/MIP-3 alpha mRNA expression in the conjunctival epithelium of normal individuals and patients with vernal keratoconjunctivitis., PMID:25172034
MicroRNA-155 is essential for T(H)2-mediated allergen-induced eosinophilic inflammation in the lung., PMID:24373357
Lung macrophages contribute to house dust mite driven airway remodeling via HIF-1α., PMID:23935964
Cys-leukotrienes promote fibrosis in a mouse model of eosinophil-mediated respiratory inflammation., PMID:23859654
Tocilizumab infusion therapy normalizes inflammation in sporadic ALS patients., PMID:23844337
CMRF35-like molecule 1 (CLM-1) regulates eosinophil homeostasis by suppressing cellular chemotaxis., PMID:23820751
The chemokine receptor CCR3 participates in tissue remodeling during atopic skin inflammation., PMID:23702389
Chemotaxis of bone marrow derived eosinophils in vivo: a novel method to explore receptor-dependent trafficking in the mouse., PMID:23670593
Chemokine expression is upregulated in chondrocytes in diabetic fracture healing., PMID:23262028
IL-4 up-regulates epidermal chemotactic, angiogenic, and pro-inflammatory genes and down-regulates antimicrobial genes in vivo and in vitro: relevant in the pathogenesis of atopic dermatitis., PMID:23207180
CCR3 induced-p42/44 MAPK activation protects against staurosporine induced-DNA fragmentation but not apoptosis in airway smooth muscle cells., PMID:22702503
Anti-inflammatory activity of traditional Chinese medicinal herbs., PMID:24716101
Lung metastasis fails in MMTV-PyMT oncomice lacking S100A4 due to a T-cell deficiency in primary tumors., PMID:20103644
The function of CCR3 on mouse bone marrow-derived mast cells in vitro., PMID:20050333
CCR3 is a target for age-related macular degeneration diagnosis and therapy., PMID:19525930
Evaluation of eotaxin-1, -2, and -3 protein production and messenger RNA expression in patients with vernal keratoconjunctivitis., PMID:19333691
A dual activation and inhibition role for the paired immunoglobulin-like receptor B in eosinophils., PMID:18316626
[Role of eotaxin in the pathophysiology of asthma]., PMID:17973226
Eotaxin-1/CC chemokine ligand 11: a novel eosinophil survival factor secreted by human pulmonary artery endothelial cells., PMID:17617619
Inflammatory responses to pneumovirus infection in IFN-alpha beta R gene-deleted mice., PMID:16177121
New chemokine targets for asthma therapy., PMID:15683617
Concerted expression of eotaxin-1, eotaxin-2, and eotaxin-3 in human bronchial epithelial cells., PMID:14698143
Eotaxins and CCR3 receptor in inflammatory and allergic skin diseases: therapeutical implications., PMID:14561178
CCR3 functional responses are regulated by both CXCR3 and its ligands CXCL9, CXCL10 and CXCL11., PMID:12884299
Expression of a functional eotaxin (CC chemokine ligand 11) receptor CCR3 by human dendritic cells., PMID:12218106
Eotaxin (CCL11) and eotaxin-2 (CCL24) induce recruitment of eosinophils, basophils, neutrophils, and macrophages as well as features of early- and late-phase allergic reactions following cutaneous injection in human atopic and nonatopic volunteers., PMID:12193745
Detection of mRNA for eotaxin-2 and eotaxin-3 in human dermal fibroblasts and their distinct activation profile on human eosinophils., PMID:11286614
Analysis of eosinophils and myeloid progenitor responses to modified forms of MPIF-2., PMID:11237428
For research use only. Not for human or drug use.
