Catalog No.
VHC79201
Species reactivity
Human
Host species
Human
Isotype
VHH-hFc
Clonality
Monoclonal
Target
Tonsillar lymphocyte LD78 alpha protein, CCL3, G0S19-1, MIP1A, Macrophage inflammatory protein 1-alpha, LD78-alpha(4-69), SCYA3, SIS-beta, Small-inducible cytokine A3, C-C motif chemokine 3, G0/G1 switch regulatory protein 19-1, PAT 464.1, MIP-1-alpha
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P10147
Applications
ELISA, Neutralization
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
Iv0078
Integration of Network Pharmacology, Transcriptomics, and Metabolomics Strategies to Uncover the Mechanism of Chaihuang Qingfu Pill in Treating Sepsis-Induced Liver Injury., PMID:40486124
In silico prediction of differentially expressed genes and functionally grouped networks in patients with inflamed pulp for screening pulpitis biomarkers., PMID:40453410
Loss of TACC2 impairs chemokine CCL3 and CCL4 expression and reduces response to anti-PD-1 therapy in soft tissue sarcoma., PMID:40442694
Comparative Analysis of Cytokine Expression Profiles in Prostate Cancer Patients., PMID:40427694
Identification and Exploration of Pyroptosis-Related Genes in Macrophage Cells Reveal Necrotizing Enterocolitis Heterogeneity Through Single-Cell and Bulk-Sequencing., PMID:40362275
Monocytes/macrophages contamination disrupts functional and transcriptional characteristics of murine bone marrow- and bone-derived stromal cells., PMID:40329992
Soluble TREM-1 ameliorates gouty arthritis by selective inhibition of proinflammatory cytokines and chemokines without affecting TGFβ production., PMID:40314990
LPS-induced extracellular AREG triggers macrophage pyroptosis through the EGFR/TLR4 signaling pathway., PMID:40292295
Genetic deletion of G protein-coupled receptor 56 aggravates traumatic brain injury through the microglial CCL3/4/5 upregulation targeted to CCR5., PMID:40089481
Adipose-derived stem cells attenuate rheumatoid arthritis by restoring CX3CR1+ synovial lining macrophage barrier., PMID:40038808
Targeted delivery of CCL3 reprograms macrophage antigen presentation and enhances the efficacy of immune checkpoint blockade therapy in hepatocellular carcinoma., PMID:39988347
Identification of CCL3 as a Schwann cell chemotactic factor essential for nerve regeneration., PMID:39960833
CD22 modulation alleviates amyloid β-induced neuroinflammation., PMID:39910617
mTOR downregulation promotes anti-inflammatory responses via the CCL3-CCR5 axis in hypoxic retinopathy., PMID:39897639
Sinensetin attenuates LPS-induced acute pulmonary inflammation in mice and RAW264.7 cells by modulating NF-κB p65-mediated immune resistance and STAT3-mediated tissue resilience., PMID:39827664
ERG mediates the differentiation of hepatic progenitor cells towards immunosuppressive PDGFRα+ cancer-associated fibroblasts during hepatocarcinogenesis., PMID:39827226
Progesterone suppresses rhinovirus-induced airway inflammation by inhibiting neutrophil infiltration and extracellular traps formation., PMID:39626540
A novel CCL3-HMGB1 signaling axis regulating osteocyte RANKL expression in multiple myeloma., PMID:39605211
Tristetraprolin-mediated mRNA destabilization regulates basophil inflammatory responses., PMID:39550253
Programmed Death Ligand-1 in Melanoma and Extracellular Vesicles Promotes Local and Regional Immune Suppression through M2-like Macrophage Polarization., PMID:39481645
Brain temperature, brain metabolites, and immune system phenotypes in temporal lobe epilepsy., PMID:39470707
Nrf2 deficiency in muscle attenuates experimental autoimmune myositis-induced muscle weakness., PMID:39429109
Exploring common pathogenic association between Epstein Barr virus infection and long-COVID by integrating RNA-Seq and molecular dynamics simulations., PMID:39391317
Targeting PADI2 as a potential therapeutic strategy against metastasis in oral cancer via suppressing EMT-mediated migration and invasion and CCL3/5-induced angiogenesis., PMID:39215870
Machine Learning-Driven Biomarker Discovery for Skeletal Complications in Type 1 Gaucher Disease Patients., PMID:39201273
Programmed surface platform orchestrates anti-bacterial ability and time-sequential bone healing for implant-associated infection., PMID:39190942
The hypervirulent Group B Streptococcus HvgA adhesin promotes central nervous system invasion through transcellular crossing of the choroid plexus., PMID:39152442
Sciatic nerve stimulation alleviates neuropathic pain and associated neuroinflammation in the dorsal root ganglia in a rodent model., PMID:39143617
Flagellin Restricts HIV-1 Infection of Macrophages through Modulation of Viral Entry Receptors and CC Chemokines., PMID:39066226
Alteration of β-glucan in the emerging fungal pathogen Candida auris leads to immune evasion and increased virulence., PMID:38967888
Herpes simplex virus spreads rapidly in human foreskin, partly driven by chemokine-induced redistribution of Nectin-1 on keratinocytes., PMID:38857290
S100A8-Mediated Inflammatory Signaling Drives Colorectal Cancer Progression via the CXCL5/CXCR2 Axis., PMID:38817853
KAT7 serves as an oncogenic gene and regulates CCL3 expression via STAT1 signaling in osteosarcoma., PMID:38797155
Monocytes expressing activin A and CCR2 exacerbate chronic testicular inflammation by promoting immune cell infiltration., PMID:38775335
Deciphering the potential role of PGRN in regulating CD8+ T cell antitumor immunity., PMID:38744851
Epigenetic mechanisms regulate sex differences in cardiac reparative functions of bone marrow progenitor cells., PMID:38684697
Dual fluorescence reporter mice for Ccl3 transcription, translation, and intercellular communication., PMID:38661718
Efficacy of LCMV-based cancer immunotherapies is unleashed by intratumoral injections of polyI:C., PMID:38631714
Repositioning of the Antihyperlipidemic Drug Fenofibrate for the Management of Aeromonas Infections., PMID:38543516
scRNA-seq analysis discovered suppression of immunomodulatory dependent inflammatory response in PMBCs exposed to silver nanoparticles., PMID:38494495
Expression of the chemokine receptor CCR1 decreases sensitivity to bortezomib in multiple myeloma cell lines., PMID:38479337
HSPB1 promotes tumor invasion by inducing angiogenesis in PitNETs., PMID:38457246
CD274 (PD-L1) negatively regulates M1 macrophage polarization in ALI/ARDS., PMID:38440722
A Novel Bionebulizer Approach to Study the Effects of Natural Mineral Water on a 3D In Vitro Nasal Model from Allergic Rhinitis Patients., PMID:38398010
The interplay of Cxcl10+/Mmp14+ monocytes and Ccl3+ neutrophils proactively mediates silica-induced pulmonary fibrosis., PMID:38335607
Chemokine receptor distribution on the surface of repolarizing T cells., PMID:38327056
Insight into the mechanism of melatonin in attenuating PCB126-induced liver injury: Resistance to ROS-dependent NETs formation to alleviate inflammation and lipid metabolism dysfunction., PMID:38171107
A New Synthetic Curcuminoid Displays Antitumor Activities in Metastasized Melanoma., PMID:37998354
Biomarkers of ocular allergy and dry eye disease., PMID:37876509
Modeling mechanisms underlying differential inflammatory responses to COVID-19 in type 2 diabetes using a patient-derived microphysiological organ-on-a-chip system., PMID:37766577
For research use only. Not for human or drug use.
