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InVivoMAb Anti-Human NGF/Beta-NGF (Iv0066)

Catalog #:   VHB91701 Specific References (49) DATASHEET
Host species: Human
Isotype: IgG2, kappa
Applications: ELISA, FCM, Neutralization
Accession: P01138
Overview

Catalog No.

VHB91701

Species reactivity

Human

Host species

Human

Isotype

IgG2, kappa

Clonality

Monoclonal

Target

Beta-nerve growth factor, NGFB, Beta-NGF, NGF

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P01138

Applications

ELISA, FCM, Neutralization

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

Iv0066

Data Image
  • Flow-cytometry
    Flow-cytometry using anti-human NGF antibody.NCI-H460 cells were stained with an irrelevant antibody (Blue Histogram) or an anti-human NGF antibody monoclonal antibody (Catalog # VHB91701 ,Green Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a FITC conjugated goat anti-human antibody (Catalog # PHB96441) and cells analysed on a NovoCyte Flow Cytometer.
References

Triple-Cue-Guided Multichannel Hydrogel Conduit to Synergistically Enhance Peripheral Nerve Repair., PMID:40506830

Expression Profiling and Function Analysis Identified New Cumulus Cells-Expressed Genes and miRNAs Predictive of Oocyte Developmental Potential., PMID:40497967

3D Printed Microsphere-Hydrogel Scaffold Facilitates Restoration of Reinnervation in Bone Regeneration through Programmable Release of NGF/BMP-2 Mimetic Peptides., PMID:40468637

Therapeutic potential of NGF-enriched extracellular vesicles in modulating neuroinflammation and enhancing peripheral nerve remyelination., PMID:40420167

Light-Responsive Oxygen Generation from Chlorella Hydrogels for Facial Nerve Injury Recovery: Crosstalk between M1/M2 Macrophages and Schwann Cells., PMID:40394959

Neurotrophins of the retina and their involvement in early-stage diabetic retinopathy in an animal model of type 1 diabetes mellitus., PMID:40368327

PLAU serves as a prognostic biomarker correlated with perineural invasion in HNSCC., PMID:40319793

Neferine Ameliorates Slow-Transmitting Constipation by Inducing PINK1/Parkin-Mediated Mitophagy in Protective Enteric Glial Cells., PMID:40295194

SDF2L1 downregulation mediates high glucose-caused Schwann cell dysfunction by inhibiting nuclear import of TFEB and CREB via KPNA3., PMID:40294738

Fabrication of GDNF-Gel/HA-Mg nerve conduit and its role in repairing peripheral nerve defects., PMID:40290886

Plantamajoside Promotes NGF/TrkA Pathway to Inhibit Neuronal Apoptosis and Improve Diabetic Peripheral Neuropathy., PMID:40289624

Therapeutic Targets and Molecular Mechanisms of Calycosin in the Treatment of Depression: Insights From Chronic Mild Stress Animal Models., PMID:40260589

Inhibition of tRF- 02514 in Extracellular Vesicles Preserves Microglia Pyroptosis and Protects Against Parkinson's Disease., PMID:40254704

Tailoring osteo-immunomodulatory micro-environments via a bioactive 3D PLA scaffold to potentiate regenerative healing., PMID:40250081

Platelet-rich plasma relieves inflammation and pain by regulating M1/M2 macrophage polarization in knee osteoarthritis rats., PMID:40229323

In Vivo Tracking of Amniotic Fluid Derived Stem Cells on Acellular Nerve Graft., PMID:40117437

Dual Targeting of Neuropilin-1 and Glucose Transporter for Efficient Fluorescence Imaging of Cancer., PMID:40048021

Cortical perforation promotes bone regeneration by enhancing nerve growth factor secretion., PMID:40043613

TRPC1 downregulation enhances catecholamine secretion in adrenal chromaffin cells under metabolic syndrome conditions., PMID:40043610

Microencapsulated rrBNGF as an alternative ovulation induction method in rabbits., PMID:40025466

Nociceptive neurons promote gastric tumour progression via a CGRP-RAMP1 axis., PMID:39972142

Short-term manual acupuncture decreased markers of systemic inflammation and altered articular cartilage transcripts in the Dunkin-Hartley model of osteoarthritis., PMID:39919377

Hydrogel loaded with cerium-manganese nanoparticles and nerve growth factor enhances spinal cord injury repair by modulating immune microenvironment and promoting neuronal regeneration., PMID:39833803

In situ biosensing for cell viability and drug evaluation in 3D extracellular matrix cultures: Applications in cytoprotection of oxidative stress injury., PMID:39827479

Uncovering Hericenones from the Fruiting Bodies of Hericium erinaceus through Interdisciplinary Collaboration., PMID:39723452

CXCL10 Promotes Spinal Macrophage Recruitment via the JAK/STAT3 Pathway to Induce Pain in Experimental Autoimmune Prostatitis., PMID:39718951

Evaluating the Anticancer Properties of Novel Piscidinol A Derivatives: Insights from DFT, Molecular Docking, and Molecular Dynamics Studies., PMID:39713673

Structurally diverse chromane meroterpenoids from Rhododendron capitatum with multifunctional neuroprotective effects., PMID:39709792

Combination of anti-inflammatory therapy and RNA interference by light-inducible hybrid nanomedicine for osteoarthritis treatment., PMID:39664429

Geraniol Ameliorates Pentylenetetrazol-Induced Epilepsy, Neuroinflammation, and Oxidative Stress via Modulating the GABAergic Tract: In vitro and in vivo studies., PMID:39654600

Amplification of Metalloregulatory Proteins in Macrophages by Bioactive ZnMn@SF Hydrogels for Spinal Cord Injury Repair., PMID:39579147

Depression like-behavior and memory loss induced by methylglyoxal is associated with tryptophan depletion and oxidative stress: a new in vivo model of neurodegeneration., PMID:39574138

Nervonic acid as novel therapeutics initiates both neurogenesis and angiogenesis for comprehensive wound repair and healing., PMID:39502529

Congenital insensitivity to pain with anhidrosis: a literature review and the advocacy for stem cell therapeutic interventions., PMID:39493574

Blood brain barrier-targeted delivery of double selenium nanospheres ameliorates neural ferroptosis in Alzheimer's disease., PMID:39491374

Novel therapies for cancer-induced bone pain., PMID:39399223

Silica Nanoparticles from Melon Seed Husk Abrogated Binary Metal(loid) Mediated Cerebellar Dysfunction by Attenuation of Oxido-inflammatory Response and Upregulation of Neurotrophic Factors in Male Albino Rats., PMID:39331240

Investigation of the pharmacological mechanisms of Shenfu injection in acute pancreatitis through network pharmacology and experimental validation., PMID:39309824

Clinical-grade intranasal NGF fuels neurological and metabolic functions of Mecp2-deficient mice., PMID:39300821

Human NGF "Painless" Ocular Delivery for Retinitis Pigmentosa: An In Vivo Study., PMID:39293937

Specific mode electroacupuncture stimulation opens the blood-brain barrier of the infarcted border zone in rats during MCAO/R recovery via modulation of tight junction protein expression by VEGFA and NF-κB., PMID:39292955

Recovering skin-nerve interaction by nanoscale metal-organic framework for diabetic ulcers healing., PMID:39280583

Nerve growth factor promote VCAM-1-dependent monocyte adhesion and M2 polarization in osteosarcoma microenvironment: Implications for larotrectinib therapy., PMID:39247831

Vitamin D ameliorates memory function in association with reducing senescence and upregulating neurotrophin mRNA expression in transient global cerebral ischemic injury model in rats., PMID:39215415

CD2AP is Co-Expressed with Tropomyosin-Related Kinase A and Ras-Related Protein Rab-5A in Cholinergic Neurons of the Murine Basal Forebrain., PMID:39211110

Effect of the novel anti-NGF monoclonal antibody DS002 on the metabolomics of pain mediators, cartilage and bone., PMID:39188953

Discovery and Profiling of New Multimodal Phenylglycinamide Derivatives as Potent Antiseizure and Antinociceptive Drug Candidates., PMID:39166702

Diquafosol Improves Corneal Wound Healing by Inducing NGF Expression in an Experimental Dry Eye Model., PMID:39120282

The mode of action of IL-23 in experimental inflammatory arthritic pain and disease., PMID:39107827

Datasheet
$ 372
Product specifications
100 μg 372 1 mg 1486

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InVivoMAb Anti-Human NGF/Beta-NGF (Iv0066) [VHB91701]
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