Catalog No.
VHC12001
Species reactivity
Human
Host species
Human
Isotype
IgG1, lambda
Clonality
Monoclonal
Target
IGF-I, IGF1, Mechano growth factor, MGF, Insulin-like growth factor I, IBP1, Somatomedin-C
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P05019
Applications
ELISA, FCM, Neutralization
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
Iv0063
A human cytotrophoblast-villous endothelium-fetal organ multi-cell model and the impact on gene and protein expression in placenta cytotrophoblast, fetal hepatocytes and fetal kidney epithelial cells., PMID:40505174
IGF1/IGF1R signaling promotes the expansion of liver CSCs and serves as a potential therapeutic target in HCC., PMID:40500564
Temporal single-cell sequencing analysis reveals that GPNMB-expressing macrophages potentiate muscle regeneration., PMID:40490493
Oyster shell powder reinforced chitosan-poly(vinyl alcohol) freeze-dried composite sponge for on-site hemorrhage control., PMID:40437867
Effects of Maillard Reaction Products on Skeletal Muscle Cells: An In Vitro Study Using C2C12 Myotubes., PMID:40422892
Stress exposure affects amyotrophic lateral sclerosis pathogenesis via PI3K/Akt and focal adhesion pathways: evidence from three experimental models., PMID:40399476
Borate-modified recombinant type XVII collagen microneedles loaded with IGF-1 for the treatment of androgenetic alopecia., PMID:40398062
Heptaminol-induced metabolic liver and cardiac injuries in rats: phytochemical screening, experimental, computational modelling and pharmacological study of phoenix dactylifera seeds., PMID:40372243
Esculetin Inhibits Fat Accumulation Through Insulin/Insulin-like Growth Factor- and AMP-Activated Protein Kinase-Dependent Pathways in Caenorhabditis elegans., PMID:40362874
Synergistic Effects of Insulin-like Growth Factor-1 and Platelet-Derived Growth Factor-BB in Tendon Healing., PMID:40362278
Novel evidence in vivo: Berberine ameliorated glucocorticoid-induced post-natal growth retardation by regulating the GH/IGF-1 axis through KMT1A downregulation., PMID:40328339
Formononetin suppresses colitis-associated colon cancer by targeting lipid synthesis and mTORC2/Akt signaling., PMID:40318528
Protein-truncating variants and deletions of SHANK2 are associated with autism spectrum disorder and other neurodevelopmental concerns., PMID:40307697
Fibro-Adipogenic Progenitors require autocrine IGF-I in homeostatic and regenerating skeletal muscle., PMID:40291730
Roles of GDF9 and BMP15 in equine follicular development: in vivo content and in vitro effects of IGF1 and cortisol on granulosa cells., PMID:40289073
Artemisinin alleviates ischemic stroke injury and promotes neurogenesis through PPARγ-mediated M2 polarization of microglia., PMID:40286750
In silico design of ankyrin repeat proteins that bind to the insulin-like growth factor type 1 receptor., PMID:40286497
IGF-1 Provides Protective Role in Arteriosclerotic Cerebral Small Vessel Disease., PMID:40248881
IGF-1 signaling pathway activation promotes axonal regeneration and repair: A mechanism study on catalpol-induced functional recovery after ischemic stroke., PMID:40245961
A human cytotrophoblast-villous endothelium-fetal organ multi-cell model and the impact on gene and protein expression in placenta cytotrophoblast, fetal hepatocytes and fetal kidney epithelial cells., PMID:40236240
In silico docking, ADMET profiling, and bio-accessibility experimentation on Breynia retusa phytocompounds and in vitro validation for anti-proliferative potencies against ovarian carcinoma., PMID:40225420
Panax notoginseng improves the sensitivity of non-small cell lung cancer to cisplatin by inhibiting Akt signaling., PMID:40195058
IGF1R-Targeted Delivery of a Bridged Nucleic Acid Oligonucleotide-Peptide Conjugate for MicroRNA-21 Inhibition in Triple-Negative Breast Cancer., PMID:40161818
Burst-Free Sustained Release of Proteins from Thermal Gelling Polymer Solutions., PMID:40143039
Combined analysis of single-cell and bulk transcriptome sequencing data identifies critical glycolysis genes in idiopathic pulmonary arterial hypertension., PMID:40140873
Cinobufagin Enhances the Sensitivity of Cisplatin-Resistant Lung Cancer Cells to Chemotherapy by Inhibiting the PI3K/AKT and MAPK/ERK Pathways., PMID:40135405
Up IGF-I via high-toughness adaptive hydrogels for remodeling growth plate of children., PMID:40078882
Additive effects of ALXN2420, a GH receptor antagonist, and octreotide on IGF1 suppression in vivo., PMID:40067863
Multifunctional hydrogel targeting senescence to accelerate diabetic wound healing through promoting angiogenesis., PMID:40050885
Nuclear translocation of CDK5RAP3 regulated by NXF3 promotes the progression of gastric cancer., PMID:40032765
[Nodakenin ameliorates TNBS-induced experimental colitis in mice by inhibiting pyroptosis of intestinal epithelial cells]., PMID:40031970
Enhanced expression of dystrophin, IGF-1, CD44 and MYH3 in plasma and skeletal muscles including diaphragm of mdx mice after oral administration of Neu REFIX beta 1,3-1,6 glucan., PMID:40021828
Low-intensity-pulsed-ultrasound-treated menstrual-blood-derived mesenchymal stem cells repair endometrial injury by PI3K/AKT pathway inhibition., PMID:39979162
Phloretin and Enalapril co-administration ameliorates hyperglycemia mediated exacerbation of myocardial injury in rats., PMID:39978711
Regulation of the EGFR/PI3K/AKT signaling cascade using the Shengui Yangrong Decoction improves ovulation dysfunction and insulin resistance in polycystic ovary syndrome., PMID:39978644
The Effects of a Novel Astragalus-Based Extract (Keyfobell Powder (KFB)) on Longitudinal Bone Growth via IGF-1 Upregulation: A Potential Growth Hormone Alternative., PMID:39940274
Nano-spanlastics-loaded dissolving microneedle patches for ketotifen fumarate: advanced strategies for allergic conjunctivitis treatment and molecular insights., PMID:39934562
Therapeutic Potential and Mechanistic Insights of a Novel Synthetic α-Lactalbumin-Derived Peptide for the Treatment of Liver Fibrosis., PMID:39868009
Interaction with IGF1 overrides ANXA2-mediated anti-inflammatory functions of IGFBP5 in vivo., PMID:39867883
Targeting IGF1 to alleviate obesity through regulating energy expenditure and fat deposition., PMID:39843847
Transcriptome analysis of regenerated dermis stimulated by mechanical stretch., PMID:39842648
Update on regulation of GHRH and its actions on GH secretion in health and disease., PMID:39838154
Efficacy and mechanisms of concentrated growth factor on facial nerve rehabilitation in a rabbit model., PMID:39831451
Antibacterial and osteogenic properties of chitosan-polyethylene glycol nanofibre-coated 3D printed scaffold with vancomycin and insulin-like growth factor-1 release for bone repair., PMID:39818389
The tRF-33/IGF1 axis dysregulates mitochondrial homeostasis in HER2-negative breast cancer., PMID:39792150
Scabiosa artropurperea var.maritima aqueous extracts improve in vivo fertility parameters and in vitro granulosa cell steroidogenesis in Ewe., PMID:39753056
Microcystin-LR induces neuronal damage through mitophagy defects resulted from the downregulated transcription of Scd2 by directly targeting IGF-1R., PMID:39725202
Integrative metabolomic-proteomic analysis uncovers a new therapeutic approach in targeting rheumatoid arthritis., PMID:39716302
Negative feedback between PTH1R and IGF1 through the Hedgehog pathway in mediating craniofacial bone remodeling., PMID:39688917
For research use only. Not for human or drug use.
