GDF11 Alleviates Vascular Calcification in VitD3-Overloaded Mice Through Inhibition of Inflammatory NF-κB Signal., PMID:40432427
ActRII or BMPR ligands inhibit skeletal myoblast differentiation, and BMPs promote heterotopic ossification in skeletal muscles in mice., PMID:39994804
Recombinant GDF11 Promotes Recovery in a Rat Permanent Ischemia Model of Subacute Stroke., PMID:39909827
GDF11 promotes osteogenic/odontogenic differentiation of dental pulp stem cells to accelerate dentin restoration via modulating SIRT3/FOXO3-mediated mitophagy., PMID:39317051
Growth Differentiation Factor 11 Evokes Lung Injury, Inflammation, and Fibrosis in Mice through the Activin A Receptor Type II-Like Kinase, 53kDa-Smad2/3 Signaling Pathway., PMID:39147236
GDF11 protects against mitochondrial-dysfunction-dependent NLRP3 inflammasome activation to attenuate osteoarthritis., PMID:39103049
Liraglutide reduces bone marrow adipogenesis by miR-150-5p/ GDF11 axis in diabetic rats., PMID:38960061
GDF11 OVEREXPRESSION ALLEVIATES SEPSIS-INDUCED LUNG MICROVASCULAR ENDOTHELIAL BARRIER DAMAGE BY ACTIVATING SIRT1/NOX4 SIGNALING TO INHIBIT FERROPTOSIS., PMID:38920138
Hapln1 promotes dedifferentiation and proliferation of iPSC-derived cardiomyocytes by promoting versican-based GDF11 trapping., PMID:38618242
GDF11 and aging biology - controversies resolved and pending., PMID:38235060
Growth differentiation factor 11 suppresses intrahepatic inflammation via restricting NLRP3 inflammasome activation in LPS-induced liver injury., PMID:38158658
Silencing of GDF11 suppresses hepatocyte apoptosis to relieve LPS/D-GalN acute liver failure., PMID:37934488
Oncogenic miR-106b-5p promotes cisplatin resistance in triple-negative breast cancer by targeting GDF11., PMID:37905957
Activin E is a TGFβ ligand that signals specifically through activin receptor-like kinase 7., PMID:37808681
Mutual regulation between GDF11 and TET2 prevents senescence of mesenchymal stem cells., PMID:37801347
Growth differentiation factor 11 delivered by dairy Lactococcus lactis strains modulates inflammation and prevents mucosal damage in a mice model of intestinal mucositis., PMID:37138633
In vivo modulation of endogenous gene expression via CRISPR/Cas9-mediated 3'UTR editing., PMID:36923835
hPSC-derived sacral neural crest enables rescue in a severe model of Hirschsprung's disease., PMID:36868194
GDF11, a target of miR-32-5p, suppresses high-glucose-induced mitochondrial dysfunction and apoptosis in HK-2 cells through PI3K/AKT signaling activation., PMID:36749472
Functional substitutions of amino acids that differ between GDF11 and GDF8 impact skeletal development and skeletal muscle., PMID:36631218
Multifaceted Benefits of GDF11 Treatment in Spinal Cord Injury: In Vitro and In Vivo Studies., PMID:36613862
All-fiber SPR microfluidic chip for GDF11 detection., PMID:36589582
Mesenchymal stem cells alleviate aging in vitro and in vivo., PMID:36388801
Pathophysiological levels of GDF11 activate Smad2/Smad3 signaling and induce muscle atrophy in human iPSC-derived myocytes., PMID:36094432
Exosome-transmitted miR-3124-5p promotes cholangiocarcinoma development via targeting GDF11., PMID:35978818
GDF11 inhibits adipogenesis and improves mature adipocytes metabolic function via WNT/β-catenin and ALK5/SMAD2/3 pathways., PMID:35920128
Growth differentiation factor 11 induces skeletal muscle atrophy via a STAT3-dependent mechanism in pulmonary arterial hypertension., PMID:35524286
GDF11 ameliorates severe acute pancreatitis through modulating macrophage M1 and M2 polarization by targeting the TGFβR1/SMAD-2 pathway., PMID:35461108
The GDF11 Promotes Nerve Regeneration After Sciatic Nerve Injury in Adult Rats by Promoting Axon Growth and Inhibiting Neuronal Apoptosis., PMID:35059389
GDF11 enhances therapeutic functions of mesenchymal stem cells for angiogenesis., PMID:34384486
LINC01116 Facilitates Melanoma 1 Progression Via Sequestering miR-3612 and Up-regulating GDF11 and SDC3., PMID:34266696
Transdifferentiation of Human Fibroblasts into Skeletal Muscle Cells: Optimization and Assembly into Engineered Tissue Constructs through Biological Ligands., PMID:34208436
Systemic administration of monovalent follistatin-like 3-Fc-fusion protein increases muscle mass in mice., PMID:34113826
Growth differentiation factor 11 promotes differentiation of MSCs into endothelial-like cells for angiogenesis., PMID:32588524
Positive Effects of a Young Systemic Environment and High Growth Differentiation Factor 11 Levels on Chondrocyte Proliferation and Cartilage Matrix Synthesis in Old Mice., PMID:32067417
Variation in zygotic CRISPR/Cas9 gene editing outcomes generates novel reporter and deletion alleles at the Gdf11 locus., PMID:31819086
Growth differentiation factor 11 attenuates liver fibrosis via expansion of liver progenitor cells., PMID:31767630
GDF11 impairs liver regeneration in mice after partial hepatectomy., PMID:31654062
GDF11 contributes to hepatic hepcidin (HAMP) inhibition through SMURF1-mediated BMP-SMAD signalling suppression., PMID:31418854
TERT assists GDF11 to rejuvenate senescent VEGFR2+/CD133+ cells in elderly patients with myocardial infarction., PMID:31292540
Opposing Effects of Growth and Differentiation Factors in Cell-Fate Specification., PMID:31155355
GDF-11 prevents cardiomyocyte hypertrophy by maintaining the sarcoplasmic reticulum-mitochondria communication., PMID:31096010
Identification of the minimum region of flatfish myostatin propeptide (Pep45-65) for myostatin inhibition and its potential to enhance muscle growth and performance in animals., PMID:30998775
Growth differentiation factor 11 is involved in isoproterenol‑induced heart failure., PMID:30942402
GDF11 exhibits tumor suppressive properties in hepatocellular carcinoma cells by restricting clonal expansion and invasion., PMID:30890427
Recombinant growth differentiation factor 11 impairs fracture healing through inhibiting chondrocyte differentiation., PMID:30575056
GDF11 Decreases Pressure Overload-Induced Hypertrophy, but Can Cause Severe Cachexia and Premature Death., PMID:30571461
Conditioned media from human umbilical cord blood-derived mesenchymal stem cells stimulate rejuvenation function in human skin., PMID:30417126
GDF11 Antagonizes Psoriasis-like Skin Inflammation via Suppression of NF-κB Signaling Pathway., PMID:30259241
Growth differentiation factor 11 worsens hepatocellular injury and liver regeneration after liver ischemia reperfusion injury., PMID:29913561
For research use only. Not for human or drug use.
