Catalog No.
VHE26001
Species reactivity
Human
Host species
Human
Isotype
IgG1, kappa
Clonality
Monoclonal
Target
Myeloproliferative leukemia virus oncogene ligand, C-mpl ligand, Thrombopoietin, THPO, Megakaryocyte colony-stimulating factor, Megakaryocyte growth and development factor, ML, MGDF
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P40225
Applications
ELISA, Neutralization
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
Iv0056
Paclitaxel improves thrombopoiesis in the absence of thrombopoietin receptor (Mpl)., PMID:39307245
Integrative investigation of hematotoxic effects induced by low doses of lead, cadmium, mercury and arsenic mixture: In vivo and in silico approach., PMID:38653421
Generation of a thrombopoietin-deficient thrombocytopenia model in zebrafish., PMID:35622056
Thrombopoietin from hepatocytes promotes hematopoietic stem cell regeneration after myeloablation., PMID:34463253
[Efficacy of thrombopoietin in bone marrow failure]., PMID:33162439
Augmentation of NK Cell Proliferation and Anti-tumor Immunity by Transgenic Expression of Receptors for EPO or TPO., PMID:33010232
HB-EGF Improves the Hair Regenerative Potential of Adipose-Derived Stem Cells via ROS Generation and Hck Phosphorylation., PMID:31878047
Tuning the properties of tris(hydroxypyridinone) ligands: efficient 68Ga chelators for PET imaging., PMID:30860215
Thrombopoietin Metabolically Primes Hematopoietic Stem Cells to Megakaryocyte-Lineage Differentiation., PMID:30428347
CD34 Antigen and the MPL Receptor Expression Defines a Novel Class of Human Cord Blood-Derived Primitive Hematopoietic Stem Cells., PMID:27938494
Sensing of the microbiota by NOD1 in mesenchymal stromal cells regulates murine hematopoiesis., PMID:27799160
FH535, a β-catenin pathway inhibitor, represses pancreatic cancer xenograft growth and angiogenesis., PMID:27323403
Heterogeneity of leukemia-initiating capacity of chronic myelogenous leukemia stem cells., PMID:26878174
Inhibition of Thrombopoietin/Mpl Signaling in Adult Hematopoiesis Identifies New Candidates for Hematopoietic Stem Cell Maintenance., PMID:26147434
Ott1 (Rbm15) regulates thrombopoietin response in hematopoietic stem cells through alternative splicing of c-Mpl., PMID:25468569
Definition of a Family of Tissue-Protective Cytokines Using Functional Cluster Analysis: A Proof-of-Concept Study., PMID:24672526
Exome sequencing reveals a thrombopoietin ligand mutation in a Micronesian family with autosomal recessive aplastic anemia., PMID:24085763
Diurnal expression of the thrombopoietin gene is regulated by CLOCK., PMID:22284746
Lentiviral gene transfer regenerates hematopoietic stem cells in a mouse model for Mpl-deficient aplastic anemia., PMID:21289307
Feasibility Evaluation of Detecting Hydroxymethylphosphine Oxide In Vivo by (31)P-MRS., PMID:23675197
Thrombopoietin/MPL signaling regulates hematopoietic stem cell quiescence and interaction with the osteoblastic niche., PMID:18371409
Complex splicing control of the human Thrombopoietin gene by intronic G runs., PMID:17158158
A novel selective gamma-aminobutyric acid transport inhibitor demonstrates a functional role for GABA transporter subtype GAT2/BGT-1 in the CNS., PMID:16517017
Maillard reaction-like lysine modification by a lipid peroxidation product: immunochemical detection of protein-bound 2-hydroxyheptanal in vivo., PMID:12914770
Characterization of discriminative stimulus effects of the neuroactive steroid pregnanolone., PMID:11303034
In vivo muscarinic cholinergic mediated effects of Lu 25-109, a M1 agonist and M2/M3 antagonist in vitro., PMID:9683000
Sleep promoting effect of a putative glial gamma-aminobutyric acid uptake blocker applied in the thalamus of cats., PMID:1839983
Pharmacological profile of a novel class of muscarinic acetylcholine receptor agonists., PMID:3780854
Somatic and dendritic actions of gamma-aminobutyric acid agonists and uptake blockers in the hippocampus in vivo., PMID:6087200
For research use only. Not for human or drug use.
