Catalog No.
VHB94401
Species reactivity
Human
Host species
Human
Isotype
IgG1, kappa
Clonality
Monoclonal
Target
TNF, Tumor necrosis factor ligand superfamily member 2, N-terminal fragment, ICD2, NTF, TNF-a, TNF-alpha, Tumor necrosis factor, TNFSF2, TNFA, Cachectin, ICD1
Concentration
1.3 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P01375
Applications
ELISA, FCM, Neutralization
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
Iv0050
Hepatocyte necroptosis is associated with liver damage in dairy cows with ketosis., PMID:40513868
Sinhyotaklisan as a Potential Therapeutic for Psoriasis: Network Pharmacology and Experimental Validation., PMID:40507893
Damage Associated Molecular Patterns (DAMPs) Mediate the Foreign Body Response to Poly(ethylene glycol) Diacrylate Hydrogels via Toll like Receptors., PMID:40504683
Anti-TNF-α antisense-oligonucleotide-conjugated PLG nanoparticles protect transplanted islets., PMID:40496001
Unlocking the therapeutic potential of protocatechualdehyde: pharmacological applications and mechanism insights., PMID:40493248
Ginsenoside Rg1 alleviates PCPA-induced insomnia by inhibiting NLRP3 inflammasome activation and pyroptosis through the Nrf2/HO-1 pathway in mice., PMID:40493075
Altered Neuroplasticity in Epilepsy is Associated with Neuroinflammation and Oxidative Stress: In vivo Evidence of Brain-Derived Extracellular Vesicles., PMID:40491852
High doses of the galactooligosaccharides, 2'-fucosyllactose alleviate immunodeficiency in vitro and in vivo., PMID:40488907
Inhibiting NLRP3/Caspase-1/GSDMD-Mediated Pyroptosis: A New Role of GADD45B's Role in Hypertriglyceridemia-Induced Acute Pancreatitis., PMID:40485526
Tumor necrosis factor alpha-induced activation of SREBP2 promotes cholesterol biosynthesis in cholestasis., PMID:40484275
PD-1-dependent therapeutic effect of Trichinella spiralis cystatin on myocardial infarction in a mice model., PMID:40474292
LOXL2 Deletion Triggers TMJ Osteoarthritis While Overexpression Protects Against NF-κβ-Induced Chondrocyte Apoptosis., PMID:40463059
TNFα activation of the PLEKHA5-FCRLA axis disturbs lipid metabolism, leading to the progression of cutaneous malignant melanoma., PMID:40462127
[Polysaccharide extract PCP1 from Polygonatum cyrtonema ameliorates cerebral ischemia-reperfusion injury in rats by inhibiting TLR4/NLRP3 pathway]., PMID:40461201
Bioinformatics prediction and experimental verification identify B4GALT1 as a diagnostic biomarker of glioblastoma., PMID:40460949
TNFAIP3 regulates inflammatory arthritis through the differentiation of monocytes into macrophages., PMID:40459867
CXCL10highTNFαhighKi67+ Microglia Recruit and Activate CD8+ T Cells in the Brainstem During Experimental Cerebral Malaria., PMID:40457525
Ubiquitin C-terminal hydrolase L1 promoted pro-angiogenic capacity of periodontal ligament stem cells via HIF-1α/YAP signaling in periodontitis., PMID:40457476
The E3 ubiquitin ligase MARCH2 controls TNF-α mediated inflammation by autoubiquitination., PMID:40450320
3,4-Dihydroxybenzoic acid methyl ester from Vespa velutina auraria Smith against rheumatoid arthritis via modulating the apoptosis and inflammation through NF-κB pathway., PMID:40448819
Curcumin alleviates lipopolysaccharide-induced alveolar epithelial Glycocalyx damage by modulating the Rac1/NF-κB/HPSE pathway., PMID:40441470
MAP2K2 Knockdown Suppresses Phenotypic Transformation of Vascular Smooth Muscle Cells in Aortic Dissection by Inactivating the JAK/STAT Signaling Pathway., PMID:40437968
Itaconate derivative 4-OI inhibits M1 macrophage polarization and restores its impaired function in immune thrombocytopenia through metabolic reprogramming., PMID:40437667
MST1 modulates inflammatory responses by targeting the NF-κB/NLRP3 pathway in LPS-induced acute lung injury., PMID:40434446
Impact of Enterococcus faecium Kimate-X on Reducing Stress in Dogs Through Gut Microbiota Modulation., PMID:40431505
3-Deoxysappanchalcone Inhibited High Mobility Group Box Protein 1-Mediated Severe Inflammatory Responses., PMID:40430548
FGF-21 fusion proteins ameliorate atopic dermatitis by inhibiting the TLR/TSLP signaling pathway: Anti-inflammatory and skin barrier repair effects., PMID:40424659
Compound 3d Attenuates Metabolic Dysfunction-Associated Steatohepatitis via Peroxisome Proliferator-Activated Receptor Pathway Activation and Inhibition of Inflammatory and Apoptotic Signaling., PMID:40422873
Nesfatin-1 Suppresses Inflammation in Bronchopulmonary Dysplasia by Regulating HMGB-1/TLR4/p65/NLRP3 Signaling Pathway., PMID:40415368
Protective Effect of Resveratrol Against Peri-Implant Inflammation and Oxidative Stress: An in vivo Study., PMID:40415361
Therapeutic potential of plant-derived small extracellular vesicles in sepsis: A network meta-analysis., PMID:40414583
Adoptively transferred macrophages for cancer immunotherapy., PMID:40413021
Hepatoprotective and antioxidant effects of Celosia trigyna and Euphorbia hirta in mitigating paracetamol-induced liver toxicity: bridging ethnomedicine and modern pharmacology., PMID:40401238
Stimulation of Soluble Guanylyl Cyclase (sGC) by Cinaciguat Attenuates Sepsisinduced Cardiac Injury., PMID:40396316
Vitamin D inhibits apoptosis in THP-1 cells infected with mycobacterium tuberculosis through TNF signaling pathway., PMID:40396181
Light-Responsive Oxygen Generation from Chlorella Hydrogels for Facial Nerve Injury Recovery: Crosstalk between M1/M2 Macrophages and Schwann Cells., PMID:40394959
TNFα Receptor 1 and Not Receptor 2 Affect Annulus Fibrosus and Nucleus Pulposus Response to Cytokine Challenge in a Rat Model., PMID:40391206
Restoring Prostacyclin/PGI2-PTGIR signaling alleviates intestinal fibrosis in Crohn's disease via fibroblast-specific YAP/TAZ inhibition., PMID:40390655
The leptin/BDNF/TrkB signaling pathway improves corticosteroid combined with chronic restraint stress-induced depressive-like behavior in mice., PMID:40389053
FXR activation suppresses NF-κB signaling, proliferation and migration in cervical cancer cells., PMID:40386262
Comprehensive analysis of protective effects of Loranthus tanakae Franch. and Sav. on ovalbumin-induced atopic dermatitis in mice and TNF-α/INF-γ-stimulated HaCaT cells., PMID:40385597
Efficacy of sodium new houttuyfonate against Aspergillus flavus: insights from in vitro and in vivo models of invasive pulmonary aspergillosis., PMID:40385476
Pharmacological activation of NO-sensitive guanylyl cyclase ameliorates obesity-induced arterial stiffness., PMID:40383495
A novel approach in reducing hypercholesterolemia using modified mango kernel starch and its role as a potential fat replacer., PMID:40382070
Size-controlled immunomodulatory and vaccine adjuvant potentials of self-assembled hyaluronic acid nanoparticles: Activation and recruitment of immune cells., PMID:40381765
Ginsenoside Rg3 alleviates brain damage caused by chlorpyrifos exposure by targeting and regulating the microbial-gut-brain axis., PMID:40381500
Deoxypodophyllotoxin inhibited the growth of malignant pleural mesothelioma by inducing necroptosis and mitotic catastrophe., PMID:40378591
Perillaldehyde protect chondrocytes from mitophagy-associated apoptosis and NLRP3-mediated inflammation by regulating ALOX5/NF-kB signaling in osteoarthritis., PMID:40378435
Effect of peripheral adiponectin on perioperative neurocognitive disorder via regulation of glucose metabolism in aged rats., PMID:40377973
Exosome miR-152-3p derived from small intestinal epithelium modulates aging process in adipocytes., PMID:40375937
For research use only. Not for human or drug use.
