InVivoMAb Anti-Rotavirus A/RV-A Outer capsid protein VP4 (Iv0013)

Catalog No.

VVV20201

Species reactivity

Rotavirus A, Rotavirus A (strain RVA/Human/United States/Wa/1974/G1P1A[8]) (RV-A)

Host species

Mouse

Isotype

IgG2a, kappa

Clonality

Monoclonal

Applications

ELISA, Neutralization

Target

Outer capsid protein VP4, VP4, Hemagglutinin

Concentration

2.5 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q2VE61, P11193, A0A385LUU7, A0A4D6QBC5

Form

Liquid

Storage buffer

PBS pH 7.4, 0.2M Arg

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

Iv0013

Note

For research use only. Not suitable for clinical or therapeutic use.

Identification and partial characterization of a rhesus rotavirus binding glycoprotein on murine enterocytes., PMID:1649504

Murine rotavirus genes encoding outer capsid proteins VP4 and VP7 are not major determinants of host range restriction and virulence., PMID:8386262

Recovery and characterization of a rotavirus outer capsid protein expressed in a recombinant insect cell system., PMID:8390880

Three-dimensional visualization of the rotavirus hemagglutinin structure., PMID:8395350

Characterization of two rotaviruses differing in their in vitro and in vivo virulence., PMID:8117825

Molecular determinants of rotavirus virulence: localization of a potential virulence site in a murine rotavirus VP4., PMID:7924250

Cleavage of rotavirus VP4 in vivo., PMID:8601772

Protective effect of rotavirus VP6-specific IgA monoclonal antibodies that lack neutralizing activity., PMID:8600516

Inhibition of rotavirus replication by a non-neutralizing, rotavirus VP6-specific IgA mAb., PMID:11994409

Selection of single-chain antibodies against the VP8* subunit of rotavirus VP4 outer capsid protein and their expression in Lactobacillus casei., PMID:15528568

Trypsin is associated with the rotavirus capsid and is activated by solubilization of outer capsid proteins., PMID:16227238

Assembly of highly infectious rotavirus particles recoated with recombinant outer capsid proteins., PMID:16971442

Llama-derived single-chain antibody fragments directed to rotavirus VP6 protein possess broad neutralizing activity in vitro and confer protection against diarrhea in mice., PMID:18632867

The C Terminus of Rotavirus VP4 Protein Contains an Actin Binding Domain Which Requires Cooperation with the Coiled-Coil Domain for Actin Remodeling., PMID:30333172

Characterization of Sialic Acid-Independent Simian Rotavirus Mutants in Viral Infection and Pathogenesis., PMID:36602365

Immunoinformatics-driven design of a multi-epitope vaccine targeting neonatal rotavirus with focus on outer capsid proteins VP4 and VP7 and non structural proteins NSP2 and NSP5., PMID:40195509

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InVivoMAb Anti-Rotavirus A/RV-A Outer capsid protein VP4 (Iv0013).pdf