Hidden dUTPase sequence in human immunodeficiency virus type 1 gp120. PMID: 9847382
HIV-1 gp120 and immune network. PMID: 15370273
The alpha helix 1 from the first conserved region of HIV1 gp120 is reconstructed in the short NQ21 peptide. PMID: 29273432
The HIV-1 gp120 V1V2 loop: structure, function and importance for vaccine development. PMID: 25163695
Entry inhibitors directed towards glycoprotein gp120: an overview on a promising target for HIV-1 therapy. PMID: 23278399
The SPL7013 dendrimer destabilizes the HIV-1 gp120-CD4 complex. PMID: 26495445
HIV gp120: double lock strategy foils host defences. PMID: 9739096
Mutational pressure makes HIV1 gp120 linear B-cell epitopes shorter and may lead to their disappearance. PMID: 20129670
Gp120 on HIV-1 Virions Lacks O-Linked Carbohydrate. PMID: 25915761
Plugging gp120s cavity. PMID: 19000812
Molecular mechanism of HIV-1 gp120 mutations that reduce CD4 binding affinity. PMID: 23297802
Viral surface glycoproteins, gp120 and gp41, as potential drug targets against HIV-1: brief overview one quarter of a century past the approval of zidovudine, the first anti-retroviral drug. PMID: 21345545
Computational design, synthesis and evaluation of new sulphonamide derivatives targeting HIV-1 gp120. PMID: 31792886
NMR observation of HIV-1 gp120 conformational flexibility resulting from V3 truncation. PMID: 24819826
A modeled structure of an aptamer-gp120 complex provides insight into the mechanism of HIV-1 neutralization. PMID: 20527993
Variability in the Glycosylation Patterns of gp120 Proteins from Different Human Immunodeficiency Virus Type 1 Isolates Expressed in Different Host Cells. PMID: 34448591
The β20-β21 of gp120 is a regulatory switch for HIV-1 Env conformational transitions. PMID: 29051495
gp120: Biologic aspects of structural features. PMID: 11244037
Genetic variability of HIV-1. PMID: 8883605
[Structural mechanism of immune evasion of HIV-1 gp120 by genomic, computational, and experimental science]. PMID: 21972555
Allosteric induction of the CD4-bound conformation of HIV-1 Gp120. PMID: 24304511
Structure and Dynamics of the Native HIV-1 Env Trimer. PMID: 25762739
Potential drug targets on the HIV-1 envelope glycoproteins, gp120 and gp41. PMID: 12769725
The gp120 protein is a second determinant of decreased neurovirulence of Indian HIV-1C isolates compared to southern African HIV-1C isolates. PMID: 25188269
A non-canonical binding interface in the crystal structure of HIV-1 gp120 core in complex with CD4. PMID: 28429756
The HIV-1 gp120 major variable regions modulate cold inactivation. PMID: 23345516
Conformational characterization of aberrant disulfide-linked HIV-1 gp120 dimers secreted from overexpressing cells. PMID: 20471426
The V1/V2 loop of HIV-1 gp120 is necessary for Tat binding and consequent modulation of virus entry. PMID: 23916815
Structure-based design, synthesis and validation of CD4-mimetic small molecule inhibitors of HIV-1 entry: conversion of a viral entry agonist to an antagonist. PMID: 24502450
Structures of HIV-1 gp120 envelope glycoproteins from laboratory-adapted and primary isolates. PMID: 11188697
Structure of HIV-1 gp120 with gp41-interactive region reveals layered envelope architecture and basis of conformational mobility. PMID: 20080564
Stoichiometric parameters of HIV-1 entry. PMID: 25463598
Insight derived from molecular dynamics simulations into molecular motions, thermodynamics and kinetics of HIV-1 gp120. PMID: 25105502
[Structure and function of oligosaccharide chains of the envelope glycoprotein gp120 of human immunodeficiency virus type 1]. PMID: 1518160
The V1V2 Region of HIV-1 gp120 Forms a Five-Stranded Beta Barrel. PMID: 26018158
Binding of HIV-1 gp120 glycoprotein to silica nanoparticles modified with CD4 glycoprotein and CD4 peptide fragments. PMID: 22117536
Local conformational stability of HIV-1 gp120 in unliganded and CD4-bound states as defined by amide hydrogen/deuterium exchange. PMID: 20660185
Conformation of gp120 determines the sensitivity of HIV-1 DH012 to the entry inhibitor IC9564. PMID: 15207637
Characterization of the secreted, native gp120 and gp160 of the human immunodeficiency virus type 1. PMID: 2187500
Correlated mutations at gp120 positions 322 and 440: implications for gp120 structure. PMID: 18275085
Morphometric analysis of envelope glycoprotein gp120 distribution on HIV-1 virions. PMID: 7678271
Nonneutralizing antibodies to the CD4-binding site on the gp120 subunit of human immunodeficiency virus type 1 do not interfere with the activity of a neutralizing antibody against the same site. PMID: 12502824
Global N-Glycan Site Occupancy of HIV-1 gp120 by Metabolic Engineering and High-Resolution Intact Mass Spectrometry. PMID: 27984693
Prediction of the secondary structure of HIV-1 gp120. PMID: 8727315
HIV-1 and its resistance to peptidic carbohydrate-binding agents (CBAs): an overview. PMID: 25517345
Interaction of human immunodeficiency virus gp120 with the voltage-gated potassium channel BEC1. PMID: 20638388
Virion attachment and entry: HIV gp120 Env biotinylation, gp120 Env, or integrin ligand-binding assay. PMID: 24158809
HIV-1 entry inhibitors in the side pocket. PMID: 10555140
[Sequence variation of HIV and bioinformatics]. PMID: 15449902
Modeling of CCR5 Recognition by HIV-1 gp120: How the Viral Protein Exploits the Conformational Plasticity of the Coreceptor. PMID: 34372601
Characterization of the outer domain of the gp120 glycoprotein from human immunodeficiency virus type 1. PMID: 15542649
The HIV-1 envelope glycoprotein gp120 features four heparan sulfate binding domains, including the co-receptor binding site. PMID: 18378683
Glycosylation of the core of the HIV-1 envelope subunit protein gp120 is not required for native trimer formation or viral infectivity. PMID: 28446609
Inhibition of HIV entry by carbohydrate-binding proteins. PMID: 16569440
Binding of HIV-1 gp120 to the nicotinic receptor. PMID: 1397297
gp120 sequences from HIV type 1 subtype C early seroconverters in India. PMID: 15320993
Cyanovirin-N binds to gp120 to interfere with CD4-dependent human immunodeficiency virus type 1 virion binding, fusion, and infectivity but does not affect the CD4 binding site on gp120 or soluble CD4-induced conformational changes in gp120. PMID: 10196334
Signal peptide of HIV envelope protein impacts glycosylation and antigenicity of gp120. PMID: 29463753
Molecular docking guided structure based design of symmetrical N,N'-disubstituted urea/thiourea as HIV-1 gp120-CD4 binding inhibitors. PMID: 23777826
Fusion proteins of HIV-1 envelope glycoprotein gp120 with CD4-induced antibodies showed enhanced binding to CD4 and CD4 binding site antibodies. PMID: 22906742
Peptides derived from HIV-1 gp120 co-receptor binding domain form amyloid fibrils and enhance HIV-1 infection. PMID: 24657436
Structure of a clade C HIV-1 gp120 bound to CD4 and CD4-induced antibody reveals anti-CD4 polyreactivity. PMID: 20357769
Sequence-conserved and antibody-accessible sites in the V1V2 domain of HIV-1 gp120 envelope protein. PMID: 25051095
Docking and 3D-QSAR studies of BMS-806 analogs as HIV-1 gp120 entry inhibitors. PMID: 19410340
Characterization of human immunodeficiency virus type 1 gp120 binding to liposomes containing galactosylceramide. PMID: 8057468
Highly conserved HIV-1 gp120 glycans proximal to CD4-binding region affect viral infectivity and neutralizing antibody induction. PMID: 22192629
Glycan deletions in the HIV-1 gp120 V1/V2 domain compromise viral infectivity, sensitize the mutant virus strains to carbohydrate-binding agents and represent a specific target for therapeutic intervention. PMID: 18930512
Glycosylation is necessary for the correct folding of human immunodeficiency virus gp120 in CD4 binding. PMID: 8416385
The highly conserved layer-3 component of the HIV-1 gp120 inner domain is critical for CD4-required conformational transitions. PMID: 23255784
The role of the viral glycoprotein in HIV-1 persistence. PMID: 10065629
Antibody neutralization of human immunodeficiency virus type 1 (HIV-1). PMID: 12739253
Estimating the threshold surface density of Gp120-CCR5 complexes necessary for HIV-1 envelope-mediated cell-cell fusion. PMID: 21647388
Structure-based, targeted deglycosylation of HIV-1 gp120 and effects on neutralization sensitivity and antibody recognition. PMID: 12954207
Ethnic differences in the adaptation rate of HIV gp120 from a vaccine trial. PMID: 19604405
Combinatorial libraries, epitope structure and the prediction of protein conformations. PMID: 9078681
A model of peptide triazole entry inhibitor binding to HIV-1 gp120 and the mechanism of bridging sheet disruption. PMID: 23470147
Design, synthesis, and evaluation of HIV-1 entry inhibitors based on broadly neutralizing antibody 447-52D and gp120 V3loop interactions. PMID: 34517280
HIV gp120 V(1)/V(2) and C(2)-V(3) domains glycoprotein compatibility is required for viral replication. PMID: 11551649
Identification of human immunodeficiency virus type 1 (HIV-1) gp120-binding sites on scavenger receptor cysteine rich 1 (SRCR1) domain of gp340. PMID: 23815775
HIV-1 virion-cell interactions: an electrostatic model of pathogenicity and syncytium formation. PMID: 8018384
Global site-specific N-glycosylation analysis of HIV envelope glycoprotein. PMID: 28348411
Chemoenzymatic synthesis of high-mannose type HIV-1 gp120 glycopeptides. PMID: 12565922
Specific VpU codon changes were significantly associated with gp120 V3 tropic signatures in HIV-1 B-subtype. PMID: 23271577
The highly conserved glycan at asparagine 260 of HIV-1 gp120 is indispensable for viral entry. PMID: 22006924
Intramolecular quality control: HIV-1 envelope gp160 signal-peptide cleavage as a functional folding checkpoint. PMID: 34469718
The effects of the HIV-1 envelope protein gp120 on the production of nitric oxide and proinflammatory cytokines in mixed glial cell cultures. PMID: 8806809
CCR5 structural plasticity shapes HIV-1 phenotypic properties. PMID: 30521629
Immunoinformatic-driven design and evaluation of multi-epitope mRNA vaccine targeting HIV-1 gp120., PMID:40433366
Vaccination of nonhuman primates elicits a broadly neutralizing antibody lineage targeting a quaternary epitope on the HIV-1 Env trimer., PMID:40339576
Isolation and structure elucidation of Dm-CVNH, a new cyanovirin-N homolog with activity against SARS-CoV-2 and HIV-1., PMID:39956341
Safety and Immunogenicity of a DNA Vaccine With Subtype C gp120 Protein Adjuvanted With MF59 or AS01B: A Phase 1/2a HIV-1 Vaccine Trial., PMID:38916429
Methamphetamine Enhancement of HIV-1 gp120-Mediated NLRP3 Inflammasome Activation and Resultant Proinflammatory Responses in Rat Microglial Cultures., PMID:38612400
Methamphetamine enhancement of HIV-1 gp120-mediated NLRP3 inflammasome activation and resultant proinflammatory responses in rat microglial cultures., PMID:38168345
P2Y13 receptor involved in HIV-1 gp120 induced neuropathy in superior cervical ganglia through NLRP3 inflammasome activation., PMID:38142931
Plasma Human Immunodeficiency Virus 1 Soluble Glycoprotein 120 Association With Correlates of Immune Dysfunction and Inflammation in Antiretroviral Therapy-Treated Individuals With Undetectable Viremia., PMID:38035854
Protein Dose-Sparing Effect of AS01B Adjuvant in a Randomized Preventive HIV Vaccine Trial of ALVAC-HIV (vCP2438) and Adjuvanted Bivalent Subtype C gp120., PMID:37795976
Additional boosting to the RV144 vaccine regimen increased Fc-mediated effector function magnitude but not durability., PMID:37260254
Indoline CD4-mimetic compounds mediate potent and broad HIV-1 inhibition and sensitization to antibody-dependent cellular cytotoxicity., PMID:36961924
Aptamer-linked photonic crystal hydrogel sensor for rapid point-of-care detection of human immuno-deficiency virus-1 (HIV-1)., PMID:36827736
Myomedin replicas of gp120 V3 loop glycan epitopes recognized by PGT121 and PGT126 antibodies as non-cognate antigens for stimulation of HIV-1 broadly neutralizing antibodies., PMID:36569830
HIV-1 gp120 Protein Activates Cyclin-Dependent Kinase 1, a Possible Link to Central Nervous System Cell Death., PMID:36560797
Identification of human immunodeficiency virus -1 E protein-targeting lead compounds by pharmacophore based screening., PMID:36517066
Pharmacokinetics, metabolism and excretion of radiolabeled fostemsavir administered with or without ritonavir in healthy male subjects., PMID:36083110
Behavioral Evidence for a Tau and HIV-gp120 Interaction., PMID:35628323
NMDA receptor antagonists engender neuroprotection against gp120-induced cognitive dysfunction in rats through modulation of PKR activation, oxidative stress, ER stress and IRE1α signal pathway., PMID:35543645
Methamphetamine augments HIV-1 gp120 inhibition of synaptic transmission and plasticity in rat hippocampal slices: Implications for methamphetamine exacerbation of HIV-associated neurocognitive disorders., PMID:35337950
Win55,212-2 improves neural injury induced by HIV-1 glycoprotein 120 in rats by exciting CB2R., PMID:35157986
Red Algal Sulfated Galactan Binds and Protects Neural Cells from HIV-1 gp120 and Tat., PMID:34451811
Chemical Compounds and Computational Prediction of Their Inhibitory Effects on the HIV-1 gp120 Receptor by Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes), with Antler-Like Morphology of Fruiting Bodies., PMID:34375519
Aptamer Laden Liquid Crystals Biosensing Platform for the Detection of HIV-1 Glycoprotein-120., PMID:34068186
Liquid Crystal Based Binding Assay for Detecting HIV-1 Surface Glycoprotein., PMID:33981675
In silico analysis of molecular interactions between HIV-1 glycoprotein gp120 and TNF receptors., PMID:33813078
Sulfoglycodendrimer Therapeutics for HIV-1 and SARS-CoV-2., PMID:33786368
Magnetic Nanoparticle and Exosomal Therapeutic (M-NEXT) Effects on HIV-Associated Neurotoxicity., PMID:33389896
The barley lectin, horcolin, binds high-mannose glycans in a multivalent fashion, enabling high-affinity, specific inhibition of cellular HIV infection., PMID:32636304
Role of nanoscale antigen organization on B-cell activation probed using DNA origami., PMID:32601450
The development of a predictive model to identify potential HIV-1 attachment inhibitors., PMID:32421648
HIV gp120 Induces the Release of Proinflammatory, Angiogenic, and Lymphangiogenic Factors from Human Lung Mast Cells., PMID:32375243
Schwann cell-derived CXCL1 contributes to human immunodeficiency virus type 1 gp120-induced neuropathic pain by modulating macrophage infiltration in mice., PMID:32229220
HIV long-term non-progressors share similar features with simian immunodeficiency virus infection of chimpanzees., PMID:32223527
Fostemsavir in Adults with Multidrug-Resistant HIV-1 Infection., PMID:32212519
Landscapes of binding antibody and T-cell responses to pox-protein HIV vaccines in Thais and South Africans., PMID:31999736
Association of complement C3d receptor 2 genotypes with the acquisition of HIV infection in a trial of recombinant glycoprotein 120 vaccine., PMID:31634193
R5 HIV-1 gp120 Activates p38 MAPK to Induce Rat Cardiomyocyte Injury by the CCR5 Coreceptor., PMID:31574524
Immunogenicity of RNA Replicons Encoding HIV Env Immunogens Designed for Self-Assembly into Nanoparticles., PMID:31515132
Variability OF HIV-1 V2 env domain for integrin binding: Clinical correlates., PMID:31357165
Methadone and buprenorphine pharmacokinetics and pharmacodynamics when coadministered with fostemsavir to opioid-dependent, human immunodeficiency virus seronegative participants., PMID:30980734
Sex Differences in a Rodent Model of HIV-1-Associated Neuropathic Pain., PMID:30857270
Effects of HIV-1 gp120 and TAT-derived microvesicles on endothelial cell function., PMID:30789287
Supraspinal interaction between HIV-1-gp120 and cannabinoid analgesic effectiveness., PMID:30008083
Structural discordance in HIV-1 Vpu from brain isolate alarms amyloid fibril forming behavior- a computational perspective., PMID:29705491
Interferon-β induced in female genital epithelium by HIV-1 glycoprotein 120 via Toll-like-receptor 2 pathway acts to protect the mucosal barrier., PMID:29553138
Efaverinz and nano-gold-loaded mannosylated niosomes: a host cell-targeted topical HIV-1 prophylaxis via thermogel system., PMID:29231058
Construction and Production of HIV-VLP Harboring MPER-V3 for Potential Vaccine Study., PMID:29046160
Effects of nanoparticle-encapsulated curcumin on HIV-gp120-associated neuropathic pain induced by the P2X3 receptor in dorsal root ganglia., PMID:28962965
Peroxisome proliferator-activated receptor-gamma: potential molecular therapeutic target for HIV-1-associated brain inflammation., PMID:28886715
Improving the Immunogenicity of Native-like HIV-1 Envelope Trimers by Hyperstabilization., PMID:28834745
For research use only. Not for human or drug use.
