Catalog No.
                        FHJ53510
                        
                                            
                                            
                                            
                                            
                                            
                                            
                                            
                                            Species reactivity
                        
                        Human                        
                                                
                                            Host species
                        
                        Mouse                        
                                                
                                            Isotype
                        
                        IgG2a, kappa                        
                                                
                                            Clonality
                        
                        Monoclonal                        
                                                
                                            
                                            Conjugation
                        
                        Unconjugated                        
                                                
                                            
                                            Target
                        
                        Interleukin-22, Cytokine Zcyto18, IL-22, ZCYTO18, IL22, ILTIF, IL-TIF, IL-10-related T-cell-derived-inducible factor                        
                                                
                                            
                                            Concentration
                        
                        1 mg/ml                        
                                                
                                            Endotoxin level
                        
                        Please contact with the lab for this information.                        
                                                
                                            Purity
                        
                        >95% as determined by SDS-PAGE.                        
                                                
                                            Purification
                        
                        Protein A/G purified from cell culture supernatant.                        
                                                
                                            Accession
                        
                        Q9GZX6                        
                                                
                                            
                                            Applications
                        
                        ELISA, FCM                        
                                                
                                            Form
                        
                        Liquid                        
                                                
                                            Storage buffer
                        
                        0.01M PBS, pH 7.4, 0.09% Sodium azide.                        
                                                
                                            
                                            
                                            
                                            
                                            
                                            
                                            
                                            
                                            
                                            
                                            
                                            Stability and Storage
                        
                        Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.                        
                                                
                                            
                                            
                                                Clone ID
                            SAA0391
                            
                                                    
                                            
                                            
                                        
                 
                
                
                                            Adipose-Derived Mesenchymal Stromal/Stem Cells Reduce Inflammatory Responses and Partially Alleviate Skin Symptoms in Imiquimod-Induced Psoriasis-Like Dermatitis Model Mice., PMID:40500215
                                            Effects of Rhodobacter sphaeroides protein on growth performance, nutrient digestibility, rumen fermentation, and serum metabolites in dairy calves during the pre- and postweaning periods., PMID:40499903
                                            Crosstalk with infant-derived Th17 cells, as well as exposure to IL-22 promotes maturation of intestinal epithelial cells in an enteroid model., PMID:40375988
                                            Elevated serum levels of IL-10 family and IL-12 family cytokines in myasthenia gravis., PMID:40288071
                                            Enhanced Immunity and Infection Resistance in Mice Through Co-Expression of Porcine IL-3, IL-7, and IL-15 Fusion Molecules in Yarrowia lipolytica., PMID:40282231
                                            The emerging role of IL-22 as a potential radiosensitivity biomarker for radiation-induced intestinal injury., PMID:40199137
                                            The impact of the mRNA COVID-19 vaccine on the Th-like cytokine profile in individuals with no history of COVID-19: insights into autoimmunity targeting heat shock proteins., PMID:40160814
                                            Lipidated IL-22 Alone or Combined with Immunomodulatory Agents Improves Disease Endpoints and Promotes Mucosal Healing in a Mouse Model of Chronic Dextran Sodium Sulfate-Induced Colitis., PMID:40138118
                                            Brusatol ameliorates intestinal mucosal injury in ulcerative colitis via activating IL-22/STAT3 pathway., PMID:40101416
                                            Phenotype-endotype relationship in elderly atopic dermatitis and effects of dupilumab therapy: prospective study., PMID:40095170
                                            Deep immunophenotyping reveals circulating activated lymphocytes in individuals at risk for rheumatoid arthritis., PMID:40091833
                                            Unraveling the role of the IL-20 cytokine family in neurodegenerative diseases: Mechanisms and therapeutic insights., PMID:40068518
                                            Analysis of proinflammatory cytokine responses in Takayasu arteritis., PMID:40060124
                                            Lentinan mitigates ulcerative colitis via the IL-22 pathway to repair the compromised mucosal barrier and enhance antimicrobial defense., PMID:40054799
                                            Bispecific domain antibody attenuates airway hyperresponsiveness and pulmonary inflammation in ovalbumin-lipopolysaccharide induced asthma model by inhibiting IL-23 and TNF-α., PMID:40010628
                                            ILC3 Function as a Double-Edged Sword in EV71 Infection., PMID:40006939
                                            Uncovering the therapeutic potential of anti-tuberculoid agent Isoniazid in a model of microbial-driven Crohn's disease., PMID:39987456
                                            Role of CD4+ T cell-derived cytokines in the pathogenesis of uveitis., PMID:39909966
                                            Comprehensive analyses of immune activity in COVID-19-vaccinated idiopathic pulmonary fibrosis patients., PMID:39845961
                                            Lactobacillus reuteri Alleviates Hyperoxia-Induced BPD by Activating IL-22/STAT3 Signaling Pathway in Neonatal Mice., PMID:39687635
                                            Period circadian clock 3 is crucial for regulation of IL-22-producing type 3 innate lymphoid cells by flavonoids from Shen Ling Bai Zhu San to alleviate colitis., PMID:39672410
                                            Comparison of CD30L and OX40L Reveals CD30L as a Promising Therapeutic Target in Atopic Dermatitis., PMID:39589186
                                            Correlation of changes in inflammatory and collagen biomarkers with durable guselkumab efficacy through 2 years in participants with active psoriatic arthritis: results from a phase III randomized controlled trial., PMID:39493888
                                            Dihydroberberine alleviates Th17/Treg imbalance in premature ovarian insufficiency mice via inhibiting Rheb/mTOR signaling., PMID:39472803
                                            Outer membrane vesicles (OMVs) from Tenacibaculum maritimum as a potential vaccine against fish tenacibaculosis., PMID:39370018
                                            Emerging Biologic Therapies for the Treatment of Atopic Dermatitis., PMID:39365406
                                            Assessment of immune responses to a Comirnaty® booster following CoronaVac® vaccination in healthcare workers., PMID:39258622
                                            Comparison of serum cytokines and chemokines levels and clinical significance in patients with pemphigus vulgaris-A retrospective study., PMID:39246287
                                            Effect of Follicular T Helper and T Helper 17 Cells-Related Molecules on Disease Severity in Patients with Myasthenia Gravis., PMID:39168115
                                            Blocking IL-17a Signaling Decreases Lung Inflammation and Improves Alveolarization in Experimental Bronchopulmonary Dysplasia., PMID:39117111
                                            Noninferiority of 16-Week vs 8-Week Guselkumab Dosing in Super Responders for Maintaining Control of Psoriasis: The GUIDE Randomized Clinical Trial., PMID:39083288
                                            Immunohistopathological analyses of a case of pemphigus vegetans with antibodies against desmoglein 1 and desmocollins 1-3., PMID:39073162
                                            Endotypes of severe neutrophilic and eosinophilic asthma from multi-omics integration of U-BIOPRED sputum samples., PMID:39073027
                                            Fecal IgE Analyses Reveal a Role for Stratifying Peanut-Allergic Patients., PMID:39056464
                                            IL-22/IL-22RA1 Promotes Human Tenon's Capsule Fibroblasts Proliferation and Regulates Fibrosis Through STAT3 Signaling Pathway., PMID:39046932
                                            The extracellular serine protease from Staphylococcus epidermidis elicits a type 2-biased immune response in atopic dermatitis patients., PMID:38895118
                                            Selection and evaluation of single domain antibody against p19 subunit of IL-23 by phage display for potential use as an autoinflammatory therapeutic., PMID:38852516
                                            Gallic acid attenuates murine ulcerative colitis by promoting group 3 innate lymphocytes, affecting gut microbiota, and bile acid metabolism., PMID:38844081
                                            Synthetic BSA-conjugated disaccharide related to the Streptococcus pneumoniae serotype 3 capsular polysaccharide increases IL-17A Levels, γδ T cells, and B1 cells in mice., PMID:38840926
                                            Pancreatic beta-cell IL-22 receptor deficiency induces age-dependent dysregulation of insulin biosynthesis and systemic glucose homeostasis., PMID:38811550
                                            Elucidating the role of T-Reg related cytokines: serum transforming growth factor beta and interleukin-35 in alopecia areata., PMID:38787409
                                            Expression and diagnostic value of interleukin-22 in rheumatoid arthritis-associated interstitial lung disease., PMID:38728884
                                            The IRE1α/XBP1 pathway sustains cytokine responses of group 3 innate lymphoid cells in inflammatory bowel disease., PMID:38722686
                                            Risankizumab Concentration but not IL-22 Levels Are Associated With Clinical and Biochemical Remission in Patients With Crohn's Disease., PMID:38705437
                                            Bacterial Sphingolipids Exacerbate Colitis by Inhibiting ILC3-derived IL-22 Production., PMID:38704148
                                            Interleukin antagonists for atopic dermatitis: a new era of therapy., PMID:38656240
                                            Exposing the molecular heterogeneity of glycosylated biotherapeutics., PMID:38627419
                                            RORγt inverse agonist TF-S14 inhibits Th17 cytokines and prolongs skin allograft survival in sensitized mice., PMID:38609465
                                            Dupilumab-associated head and neck dermatitis shows a pronounced type 22 immune signature mediated by oligoclonally expanded T cells., PMID:38565563
                                            Targeting IL-13 with tralokinumab normalizes type 2 inflammation in atopic dermatitis both early and at 2 years., PMID:38563683