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Anti-Human IL21 Antibody (SAA0390)

Catalog #:   FHJ59410 Specific References (50) DATASHEET
Host species: Mouse
Isotype: IgG1, kappa
Applications: ELISA, FCM
Accession: Q9HBE4
Overview

Catalog No.

FHJ59410

Species reactivity

Human

Host species

Mouse

Isotype

IgG1, kappa

Clonality

Monoclonal

Conjugation

Unconjugated

Target

IL-21, Interleukin-21, IL21, Za11

Concentration

1.14 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q9HBE4

Applications

ELISA, FCM

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

SAA0390

Data Image
References

Serum Levels of IL-21 and IL-27 Do not Reflect differential Avidity of Anti-SARS-CoV-2 IgG Antibodies in Symptomatic and Asymptomatic COVID-19 Patients., PMID:40471646

Advances of oncolytic vaccinia viruses armed with interleukin in tumor therapy., PMID:40469178

KMT2D coordinates antiviral CD4+ T cell responses through opposing effects on T follicular helper and cytotoxic gene expression., PMID:40460200

Immunocytokines and cytokine neutralization for cancer immunotherapy., PMID:40425444

Increased Proportion of Circulating T Follicular Helper Cells and Serum Levels of IL-21 in Antibody-Mediated Rejection of Renal Allograft., PMID:40424492

The Arf pathway is required for resolving ER stress during T cell activation., PMID:40405457

The effects of interleukin-21 in the biology of transplant rejection., PMID:40376002

Trifunctional antibody-cytokine fusion protein formats for tumor-targeted combination of IL-15 with IL-7 or IL-21., PMID:40370435

The Combination of Oncolytic Virus and Antibody Blockade of TGF-β Enhances the Efficacy of αvβ6-Targeting CAR T Cells Against Pancreatic Cancer in an Immunocompetent Model., PMID:40361460

Thyrotrophin receptor antibody: objective and quantitative inflammatory indicator in patients with thyroid eye disease., PMID:40344181

IL-21R-Targeted Nano-immunosuppressant Prevents Acute Rejection in Allogeneic Transplantation by Blocking Maturation of T Follicular Helper Cells., PMID:40339970

Correlation among ocular surface changes and systemic hematologic indexes and disease activity in primary Sjögren's syndrome: a cross-sectional study., PMID:40329232

Tph cells are expanded in IgA vasculitis nephritis., PMID:40315784

T-Follicular Helper Cells and Their Role in Autoimmune Diseases., PMID:40283219

Targeted delivery of IL-21 neutralizing nanotherapeutics to lymph nodes and kidney allografts attenuates B cell alloimmunity., PMID:40268164

Differential gut microbiota and inflammatory cytokines contribute to IgA vasculitis., PMID:40201970

ICOS+CD4+ T cells define a high susceptibility to anti-PD-1 therapy-induced lung pathogenesis., PMID:40198121

Functional insights of an uncommon hypomorphic variant in IL2RG as a monogenic cause of CVID-like disease with antibody deficiency and T CD4 lymphopenia., PMID:40170851

Modulating IL-21-driven B cell responses in idiopathic inflammatory myopathies via inhibition of the JAK/STAT pathway., PMID:40170058

Emerging Novel Therapies for the Treatment of Psoriasis: A Narrative Review., PMID:40161116

Distinct features of a peripheral T helper subset that drives the B cell response in dengue virus infection., PMID:40073863

Comment on "IL-21 and IL-33 May Be Effective Biomarkers to Predict the Efficacy of PD-1 Monoclonal Antibody for Advanced Cholangiocarcinoma"., PMID:40067408

Analysis of proinflammatory cytokine responses in Takayasu arteritis., PMID:40060124

The saponin monophosphoryl lipid A nanoparticle adjuvant induces dose-dependent HIV vaccine responses in nonhuman primates., PMID:40036068

Pregnancy Reduces COVID-19 Vaccine Immunity Against Novel Variants., PMID:39974078

CD8+ Regulatory T Cells Induced by Peptide Vaccination Ameliorates Experimental Model of Membranous Nephropathy., PMID:39970933

Targeting γc family cytokines with biologics: current status and future prospects., PMID:39967341

Inhibition of IL-21/IL-21R Signaling by Fucoxanthin: Structure-Based and Experimental Analysis., PMID:39953920

Jianpi Yiqi Busui prescription alleviates myasthenia gravis by regulating Th17 through the TAK1/P38 MAPK/eIF-4E signaling pathway., PMID:39937170

IL-21 promotes plasmablast differentiation independently of proliferation in vitro., PMID:39924005

Role of CD4+ T cell-derived cytokines in the pathogenesis of uveitis., PMID:39909966

Differential Clinical and Immunological Impacts of Anti-T-Lymphocyte Globulin (ATLG) vs. Anti-Thymocyte Globulin (ATG) in Preventing Graft-Versus-Host Disease Post-Allogeneic Hematopoietic Stem Cell Transplantation: A Comparative Study., PMID:39905816

Progressively differentiated TFH13 cells are stabilized by JunB to mediate allergen germinal center responses., PMID:39891019

IL-21 signaling promotes IgM+ B cell proliferation and antibody production via JAK/STAT3 and AKT pathways in early vertebrates., PMID:39870186

Plasma membrane-coated nanoparticles and membrane vesicles to orchestrate multimodal antitumor immunity., PMID:39864848

T Cell-Specific Inactivation of the PI3K p110α Catalytic Subunit: Effect in T Cell Differentiation and Antigen-Specific Responses., PMID:39859310

IL-21 and IL-33 May Be Effective Biomarkers to Predict the Efficacy of PD-1 Monoclonal Antibody for Advanced Cholangiocarcinoma., PMID:39835991

Extracellular acyl-CoA-binding protein as an independent biomarker of COVID-19 disease severity., PMID:39835130

Dual neutralization of TGF-β and IL-21 regulates Th17/Treg balance by suppressing inflammatory signalling in the splenic lymphocytes of Staphylococcus aureus infection-induced septic arthritic mice., PMID:39831928

IL-35 modulates Tfh2 and Tfr cell balance to alleviate allergic rhinitis., PMID:39825933

IL-21 shapes the B cell response in a context-dependent manner., PMID:39792552

Function and Regulation of Age-Associated B Cells in Diseases., PMID:39749652

Induction of interleukin 21 receptor expression via enhanced intracellular metabolism in B cells and its relevance to the disease activity in systemic lupus erythematosus., PMID:39740932

1,25(OH)2D3-treated mouse bone marrow-derived dendritic cells alleviate autoimmune hepatitis in mice by improving TFR/TFH imbalance., PMID:39604017

2D4, a humanized monoclonal antibody targeting CD132, is a promising treatment for systemic lupus erythematosus., PMID:39551768

[Modification with IL-21 and CCL19 enhances killing efficiency and tumor infiltration of NKP30 CAR-T cells in lung cancer]., PMID:39523093

The role of polyreactive memory B cells in systemic lupus erythematosus., PMID:39514642

The role of alemtuzumab in the development of secondary autoimmunity in multiple Sclerosis: a systematic review., PMID:39487492

CXCL13/CXCR5 axis facilitates TFH expansion and correlates with disease severity in adults with immune thrombocytopenia., PMID:39454362

CXCL13 promotes broad immune responses induced by circular RNA vaccines., PMID:39436660

Datasheet
$ 198
Product specifications
50 μg 198 100 μg 328

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For research use only. Not for human or drug use.

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Anti-Human IL21 Antibody (SAA0390) [FHJ59410]
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