Catalog No.
FHG70710
Species reactivity
Human
Host species
Human
Isotype
IgG1, kappa
Clonality
Monoclonal
Conjugation
Unconjugated
Target
IFN-gamma-inducing factor, IL1F4, Interleukin-1 gamma, IL-18, IL-1 gamma, Interleukin-18, Interferon gamma-inducing factor, IGIF, IL18, Iboctadekin
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q14116
Applications
ELISA, FCM
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.09% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
SAA0388
Profile of Cytokines Associated with SARS-CoV2 Seropositivity in Multiple Sclerosis Patients and Its Persistence over Six Months., PMID:40507498
IL-18 inhibition enlarges lesions, necrotic cores and thickens fibrous caps in Jak2 V617F clonal hematopoiesis-driven atherosclerosis., PMID:40501724
IL-18 favors Th2 responses in sporotrichosis caused by Sporothrix globosa, prolonging the course of the disease., PMID:40489556
Luteolin Ameliorates Allergic Rhinitis in Mice through Modulating T Cell Subset Imbalance, Endoplasmic Reticulum Stress, and NLRP3 Inflammasome Axes., PMID:40471643
Shikonin inhibits NLRP3 inflammasome activation and controls inflammatory disease., PMID:40447675
Immunostimulatory effects of multiple short-hairpin RNAs enhance foot-and-mouth disease vaccine-induced humoral immunity., PMID:40441607
Immunocytokines and cytokine neutralization for cancer immunotherapy., PMID:40425444
Pro-inflammatory cytokines in myasthenia gravis: a systematic review and meta-analysis., PMID:40347402
Blocking of IL-4/IL-13 Signalling With Dupilumab Results in Restoration of Serum and Cutaneous Abnormalities in Netherton Syndrome., PMID:40344324
Immune Modulation and Efficacy of Tixagevimab/Cilgavimab Pre-Exposure Prophylaxis in Lung Transplant Recipients During the Omicron Wave., PMID:40332340
Antifibrotic effects of IL-12-treated natural killer cells on collagen type I regulation in lung fibroblasts., PMID:40328414
Effects of micro- and nanoplastic exposure on macrophages: a review of molecular and cellular mechanisms., PMID:40323219
Identification of soluble biomarkers that associate with distinct manifestations of long COVID., PMID:40307449
A cross-sectional analysis of the vaginal microenvironment in rheumatoid arthritis., PMID:40297421
Molecular and Immunometabolic Landscape of Erythrophagocytosis-induced Ferroptosis., PMID:40231500
CXCL9 and IL-18: potential biomarkers for efficacy evaluation in refractory hemophagocytic lymphohistiocytosis treated with RED (ruxolitinib, emapalumab and dexamethasone)., PMID:40186662
Memory-like Natural Killer Cell and CD19 Antibody-Based Immunotherapy in Combination with Tyrosine Kinase Inhibition Has Antitumor Effects against Ph(-like) Acute Lymphoblastic Leukemia., PMID:40168144
IL-18-primed NK cells recruit dendritic cells and potentiate tumor therapy mediated by PD-1 blockade., PMID:40165899
Pulmonary Myeloid Cells in Mild Cases of COVID-19 Upregulate the Intracellular Fc Receptor TRIM21 and Transcribe Proteasome-Associated Molecules., PMID:40141410
IL-33 facilitates endoplasmic reticulum stress and pyroptosis in LPS-stimulated ARDS model in vitro., PMID:40118005
Immunological landscape of children with Mycoplasma pneumoniae pneumonia in the post-COVID-19 era reveals distinctive severity indicators., PMID:40097989
Memory-like NK cell differentiation, inhibitory NKG2A blockade, and improved recognition via antibody or CAR engineering combine to enhance NK cell attack against multiple myeloma., PMID:40073259
Development of anti-murine IL-18 binding protein antibodies to stimulate IL-18 bioactivity., PMID:40018678
Sustained remission after bispecific antibody anti-IL-1β/anti-IL-18 therapy in a severe childhood Still's disease with recurrent macrophage activation syndrome., PMID:40015363
An Attomolar-Level Optical Device for Monitoring Receptor-Analyte Interactions Without Functionalization Steps: A Case Study of Cytokine Detection., PMID:39943569
Therapeutic plasma exchange accelerates immune cell recovery in severe COVID-19., PMID:39896810
Plasma membrane-coated nanoparticles and membrane vesicles to orchestrate multimodal antitumor immunity., PMID:39864848
Cytokine and Chemokine Responses of Peripheral Blood Mononuclear Cells from Dogs Infected with Mycobacterium bovis., PMID:39860978
Background and Clinical Features of a Unique and Mysterious Autoinflammatory Disease, Schnitzler Syndrome., PMID:39859314
IL-18 Blockage Reduces Neuroinflammation and Promotes Functional Recovery in a Mouse Model of Spinal Cord Injury., PMID:39858411
HMGB2 knockdown ameliorates retinal ganglion cell injury by inhibiting NLRP3 inflammasome activation after retinal ischemia., PMID:39829613
Nerelimomab Alleviates Capsaicin-Induced Acute Lung Injury by Inhibiting TNF Signaling and Apoptosis., PMID:39770536
Profile and Usefulness of Serum Cytokines to Predict Prognosis in Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease., PMID:39752619
Regulatory T cell expansion prevents retinal degeneration in type 2 diabetes., PMID:39716335
Platelet-neutrophil aggregate formation induces NLRP3 inflammasome activation in vaccine-induced thrombotic thrombocytopenia., PMID:39706368
Increased Herpes simplex virus 1, Toxoplasma gondii and Cytomegalovirus antibody concentrations in severe mental illness., PMID:39695093
An antibiotic that mediates immune destruction of senescent cancer cells., PMID:39693343
Advancements and challenges in immunocytokines: A new arsenal against cancer., PMID:39664443
Particulate Matter Induces NLRP3 Inflammasome-Mediated Pyroptosis in Human Nasal Epithelial Cells., PMID:39664405
Durable antitumor response via an oncolytic virus encoding decoy-resistant IL-18., PMID:39631848
Pereskia bleo augments NK cell cytotoxicity against triple-negative breast cancer cells (MDA-MB-231)., PMID:39619199
Outcome of SARS-CoV-2 reinfection depends on genetic background in female mice., PMID:39580470
Tim-3 Deficiency Ameliorates Motor Deficits and Neuroinflammation in MPP+/MPTP-Induced Parkinson's Disease Models via the NF-κB/NLRP3 Pathway., PMID:39579278
Moderate-intensity aerobic exercise inhibits cell pyroptosis to improve myocardial ischemia-reperfusion injury., PMID:39570295
CD2 expressing innate lymphoid and T cells are critical effectors of immunopathogenesis in hidradenitis suppurativa., PMID:39560648
Major alteration of lung microbiome and the host responses in critically ill COVID-19 patients with high viral load., PMID:39532981
A New Bacterial Chassis for Enhanced Surface Display of Recombinant Proteins., PMID:39513006
Very Early-Onset IBD-Associated IL-18opathy Treated with an Anti-IL-18 Antibody., PMID:39458007
Selected Interleukins Relevant to Multiple Sclerosis: New Directions, Potential Targets and Therapeutic Perspectives., PMID:39456713
Anti-peptide antibodies, anti-SNRK and anti-HUWE1 antibodies as potential predictors of good response to tofacitinib therapy in rheumatoid arthritis patients., PMID:39447044
For research use only. Not for human or drug use.
