Catalog No.
FHD83910
Species reactivity
Human
Host species
Mouse
Isotype
IgG2a, kappa
Clonality
Monoclonal
Conjugation
Unconjugated
Target
IL-12A, NK cell stimulatory factor chain 1, IL12A, CLMF p35, Interleukin-12 subunit alpha, IL-12 subunit p35, NKSF1, Cytotoxic lymphocyte maturation factor 35 kDa subunit
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P29459
Applications
ELISA, FCM
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.09% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
SAA0380
Expression of STAT3, IL27p28 and IL12p35 is deregulated and linked to autoimmune markers in chronic spontaneous urticaria., PMID:39107251
Importance of particle size of oligomannose-coated liposomes for induction of Th1 immunity., PMID:34426114
Foxp3 Silencing with Antisense Oligonucleotide Improves Immunogenicity of an Adjuvanted Recombinant Vaccine against Sporothrix schenckii., PMID:33801683
Expression of recombinant DnaK of Brucella abortus and its evaluation as immuno-modulator., PMID:33606039
Development of an immunocompetent mouse model susceptible to Cryptosporidium tyzzeri infection., PMID:33068486
LmjMAPK10 offers protection against Leishmania donovani infection., PMID:31770453
Enhanced protection against Q fever in BALB/c mice elicited by immunization of chloroform-methanol residue of Coxiella burnetii via intratracheal inoculation., PMID:31477436
Plasmacytoid dendritic cells protect against immune-mediated acute liver injury via IL-35., PMID:31264967
Increased expression of the immunosuppressive interleukin-35 in patients with non-small cell lung cancer., PMID:30956278
The analysis of the therapeutic potential of ustekinumab in psoriasis vulgaris treatment., PMID:30693647
Decreased Gene Expression of Epstein-Barr Virus-Induced Gene 3 (EBI-3) may Contribute to the Pathogenesis of Rheumatoid Arthritis., PMID:30513021
Serum level of IL-4 predicts response to topical immunotherapy with diphenylcyclopropenone in alopecia areata., PMID:30047620
T-cell profiles elicited by Toxoplasma gondii in acutely/chronically infected humans., PMID:29633283
Interleukin 35 Expression Correlates With Microvessel Density in Pancreatic Ductal Adenocarcinoma, Recruits Monocytes, and Promotes Growth and Angiogenesis of Xenograft Tumors in Mice., PMID:28989066
Titers of antibodies to the surface antigen of hepatitis B virus after vaccination in relation to immunity-related gene variants. A prospective study among hemodialysis patients., PMID:28817541
Adjuvant use of the NKT cell agonist alpha-galactosylceramide leads to enhancement of M2-based DNA vaccine immunogenicity and protective immunity against influenza A virus., PMID:28120096
Targeted Reconstitution of Cytokine Activity upon Antigen Binding using Split Cytokine Antibody Fusion Proteins., PMID:27402834
[Expression of interleukin-12 and interleukin-27 proteins and immune status in serum of patients with oral lichen planus]., PMID:27337921
Identification of the SLAM Adapter Molecule EAT-2 as a Lupus-Susceptibility Gene That Acts through Impaired Negative Regulation of Dendritic Cell Signaling., PMID:26432891
Hydrolyzed whey protein prevents the development of food allergy to β-lactoglobulin in sensitized mice., PMID:26364716
Interaction of Macrophage Antigen 1 and CD40 Ligand Leads to IL-12 Production and Resistance in CD40-Deficient Mice Infected with Leishmania major., PMID:26304989
The Human NK Cell Response to Yellow Fever Virus 17D Is Primarily Governed by NK Cell Differentiation Independently of NK Cell Education., PMID:26283480
Clinical and biological effects of an agonist anti-CD40 antibody: a Cancer Research UK phase I study., PMID:25589626
Role of dendritic cells in the pathogenesis of Whipple's disease., PMID:25385798
T follicular helper cell differentiation, function, and roles in disease., PMID:25367570
STAT4 gene polymorphisms are associated with susceptibility and ANA status in primary biliary cirrhosis., PMID:24648611
Association of the interleukin-12 polymorphic variants with the development of antibodies to surface antigen of hepatitis B virus in hemodialysis patients in response to vaccination or infection., PMID:24158609
Gene expression changes in human islets exposed to type 1 diabetic serum., PMID:22885994
Primary biliary cirrhosis associated with HLA, IL12A, and IL12RB2 variants., PMID:19458352
A role for Fli-1 in B cell proliferation: implications for SLE pathogenesis., PMID:18692443
NK026680, a novel compound suppressive of dendritic cell function, ameliorates mortality in acute lethal graft-versus-host reaction in mice., PMID:16299543
Interleukin-12 subunits p35 and p40 of Indian water buffalo (Bubalus bubalis) maintain high sequence homology with those of other ruminants., PMID:15932623
Recombinant herpes simplex virus type 1 (HSV-1) codelivering interleukin-12p35 as a molecular adjuvant enhances the protective immune response against ocular HSV-1 challenge., PMID:15731224
Production of biologically active equine interleukin 12 through expression of p35, p40 and single chain IL-12 in mammalian and baculovirus expression systems., PMID:11770992
For research use only. Not for human or drug use.
