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InVivoMAb Anti-Human IL23A (Iv0034)

Catalog #:   VHJ63101 Specific References (50) DATASHEET
Host species: Human
Isotype: IgG1, lambda
Applications: ELISA, Neutralization
Accession: Q9NPF7
Overview

Catalog No.

VHJ63101

Species reactivity

Human

Host species

Human

Isotype

IgG1, lambda

Clonality

Monoclonal

Target

SGRF, IL-23-A, IL-23 subunit alpha, Interleukin-23 subunit p19, IL23A, Interleukin-23 subunit alpha, IL-23p19

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q9NPF7

Applications

ELISA, Neutralization

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

Iv0034

Data Image
References

Oral roflumilast suppresses pro-inflammatory cytokine signaling and reduces CD4+ T cell and neutrophil infiltration in psoriasis., PMID:40403838

Pregnane X receptor reduces particulate matter-induced type 17 inflammation in atopic dermatitis., PMID:39399487

Bacterial Lysate-Based Bifunctional mRNA Nanoformulation for Efficient Colon Cancer Immunogene Therapy., PMID:39397736

Cold Plasma Ameliorates Imiquimod-Induced Psoriasis-Like Skin Inflammation in Mice., PMID:39349353

Identifying a gene signature of metastatic potential by linking pre-metastatic state to ultimate metastatic fate., PMID:39185156

The mode of action of IL-23 in experimental inflammatory arthritic pain and disease., PMID:39107827

Myelin-reactive B cells exacerbate CD4+ T cell-driven CNS autoimmunity in an IL-23-dependent manner., PMID:38926356

Innate lymphoid cell-based immunomodulatory hydrogel microspheres containing Cutibacterium acnes extracellular vesicles for the treatment of psoriasis., PMID:38871203

Topical application of activator protein-1 inhibitor T-5224 suppresses inflammation and improves skin barrier function in a murine atopic dermatitis-like dermatitis., PMID:38350816

Immune cell targeted fumaric esters support a role of GPR109A as a primary target of monomethyl fumarate in vivo., PMID:37004600

The anti-hepatocellular carcinoma effects of polysaccharides from Ganoderma lucidum by regulating macrophage polarization via the MAPK/NF-κB signaling pathway., PMID:36883482

Interleukin-23 Mediates Osteoclastogenesis in Collagen-Induced Arthritis by Modulating MicroRNA-223., PMID:36077117

Serpine1 Regulates Peripheral Neutrophil Recruitment and Acts as Potential Target in Ischemic Stroke., PMID:35494316

Cell cycle kinase CHEK2 in macrophages alleviates the inflammatory response to Staphylococcus aureus-induced pneumonia., PMID:35075953

IL-33 Coordinates Innate Defense to Systemic Candida albicans Infection by Regulating IL-23 and IL-10 in an Opposite Way., PMID:35022276

Intratumoral expression of interleukin 23 variants using oncolytic vaccinia virus elicit potent antitumor effects on multiple tumor models via tumor microenvironment modulation., PMID:34093846

Trim14 promotes osteoclastogenesis and noncanonical NF-κB activation by targeting p100/p52 in chronic periodontitis., PMID:33901321

Predicted regulatory SNPs reveal potential drug targets and novel companion diagnostics in psoriasis., PMID:33898962

Mediation of Interleukin-23 and Tumor Necrosis Factor-Driven Reactive Arthritis by Chlamydia-Infected Macrophages in SKG Mice., PMID:33452873

Differential modulation of Ahr and Arid5a: A promising therapeutic strategy for autoimmune encephalomyelitis., PMID:33424253

Daphnetin inhibits proliferation and inflammatory response in human HaCaT keratinocytes and ameliorates imiquimod-induced psoriasis-like skin lesion in mice., PMID:33081840

IL-38: A novel cytokine in systemic lupus erythematosus pathogenesis., PMID:33079487

Effects of pharmacological calcimimetics on colorectal cancer cells over-expressing the human calcium-sensing receptor., PMID:32861746

CCL2 and IL18 expressions may associate with the anti-proliferative effect of noncontact electro capacitive cancer therapy in vivo., PMID:32695310

Human neutrophils activated by TLR8 agonists, with or without IFNγ, synthesize and release EBI3, but not IL-12, IL-27, IL-35, or IL-39., PMID:32480433

Inhibition of keratinocyte necroptosis mediated by RIPK1/RIPK3/MLKL provides a protective effect against psoriatic inflammation., PMID:32075957

Autophagy-based unconventional secretion of HMGB1 by keratinocytes plays a pivotal role in psoriatic skin inflammation., PMID:32019420

Poly(ADP-ribose) polymerase-1 depletion enhances the severity of inflammation in an imiquimod-induced model of psoriasis., PMID:31755591

Interleukin-23 is constitutively expressed in the human annulus in vivo and in vitro, and is up-regulated in vitro by TNF-α., PMID:31537133

Resolvin E3 attenuates allergic airway inflammation via the interleukin-23-interleukin-17A pathway., PMID:31469599

Fate-Mapping of GM-CSF Expression Identifies a Discrete Subset of Inflammation-Driving T Helper Cells Regulated by Cytokines IL-23 and IL-1β., PMID:31079916

Suppression of autophagy and HCK signaling promotes PTGS2high FCGR3- NK cell differentiation triggered by ectopic endometrial stromal cells., PMID:29962266

MPO Promoter Polymorphism rs2333227 Enhances Malignant Phenotypes of Colorectal Cancer by Altering the Binding Affinity of AP-2α., PMID:29540402

In vivo IL-12/IL-23p40 neutralization blocks Th1/Th17 response after allogeneic hematopoietic cell transplantation., PMID:29242294

Expression of inflammatory and structural matrix genes in synovial fluid following intra-articular administration of isoflupredone acetate to exercised horses., PMID:29044706

Engrafted peripheral blood-derived mesenchymal stem cells promote locomotive recovery in adult rats after spinal cord injury., PMID:28979672

Inhibition of IL-17-committed T cells in a murine psoriasis model by a vitamin D analogue., PMID:28870465

Biofilm-Induced Type 2 Innate Immunity in a Cystic Fibrosis Model of Pseudomonas aeruginosa., PMID:28680858

Myeloid C/EBPβ deficiency reshapes microglial gene expression and is protective in experimental autoimmune encephalomyelitis., PMID:28302135

Nutritional control of IL-23/Th17-mediated autoimmune disease through HO-1/STAT3 activation., PMID:28290522

Investigating the Role of Surface Materials and Three Dimensional Architecture on In Vitro Differentiation of Porcine Monocyte-Derived Dendritic Cells., PMID:27362493

IL-12p40 Homodimer Ameliorates Experimental Autoimmune Arthritis., PMID:26324771

Interleukin-12 and -23 Control Plasticity of CD127(+) Group 1 and Group 3 Innate Lymphoid Cells in the Intestinal Lamina Propria., PMID:26187413

The effects of radio-frequency electromagnetic fields on T cell function during development., PMID:25835473

Lactobacillus acidophilus L-92 Cells Activate Expression of Immunomodulatory Genes in THP-1 Cells., PMID:25379363

Claudin-1 overexpression in intestinal epithelial cells enhances susceptibility to adenamatous polyposis coli-mediated colon tumorigenesis., PMID:24997475

Initiation of an inflammatory response in resident intestinal lamina propria cells -use of a human organ culture model., PMID:24841635

Embelin reduces colitis-associated tumorigenesis through limiting IL-6/STAT3 signaling., PMID:24651526

Sulforaphane protects from T cell-mediated autoimmune disease by inhibition of IL-23 and IL-12 in dendritic cells., PMID:24639357

IRF5 is a specific marker of inflammatory macrophages in vivo., PMID:24453413

Datasheet
$ 372
Product specifications
100 μg 372 1 mg 1486

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For research use only. Not for human or drug use.

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InVivoMAb Anti-Human IL23A (Iv0034) [VHJ63101]
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