InVivoMAb Anti-Human IL22 (Iv0033)

Catalog No.

VHJ53501

Species reactivity

Human

Host species

Mouse

Isotype

IgG1, lambda

Clonality

Monoclonal

Target

Interleukin-22, Cytokine Zcyto18, IL-22, ZCYTO18, IL22, ILTIF, IL-TIF, IL-10-related T-cell-derived-inducible factor

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q9GZX6

Applications

ELISA, Neutralization

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

Iv0033

Dissecting key contributions of Th2 and Th17 cytokines to atopic dermatitis pathophysiology., PMID:40409379

Amelioration of Imiquimod-induced Psoriasis in the Mice model by Topical Delivery of Phosphodiesterase 4 Inhibitor Roflumilast Incorporated Nanoemulgel., PMID:40372116

Lycopene Supplemented Mediterranean Diet Ameliorates Experimental Autoimmune Encephalomyelitis (EAE) in Mice and Changes Intestinal Microbiome., PMID:40323426

Enhanced Immunity and Infection Resistance in Mice Through Co-Expression of Porcine IL-3, IL-7, and IL-15 Fusion Molecules in Yarrowia lipolytica., PMID:40282231

Andrographolide sulfonate alleviates rheumatoid arthritis by inhibiting glycolysis-mediated activation of PI3K/AKT to restrain Th17 cell differentiation., PMID:40274350

ART26.12, an FABP5 Inhibitor, Shows Efficacy in Preclinical Psoriasis Models., PMID:40210114

IL-22/IL-22R1 pathway enhances cholangiocarcinoma progression via ERK1/2 activation., PMID:40092929

Knockdown of ANXA3 regulates NF-κB/STAT3 pathway to alleviate inflammation and hyperproliferation in psoriasis models., PMID:40088019

STING Deficiency Promotes Th17-Like Tfh to Aggravate the Experimental Autoimmune Uveitis., PMID:40042874

Identification of the key tryptophan metabolic characteristics of Lactiplantibacillus plantarum for aryl hydrocarbon receptor activation and ulcerative colitis alleviation., PMID:40022314

Beta-hydroxy-beta-methylbutyrate (HMB) ameliorates DSS-induced colitis by inhibiting ERK/NF-κB activation in macrophages., PMID:39978274

Protective and Anti-Inflammatory Effect of Novel Formulation Based on High and Low Molecular Weight Hyaluronic Acid and Salvia haenkei., PMID:39941078

Microbial remodeling of gut tryptophan metabolism and indole-3-lactate production regulate epithelial barrier repair and viral suppression in human and simian immunodeficiency virus infections., PMID:39894082

Evaluation of In Vitro Production Capabilities of Indole Derivatives by Lactic Acid Bacteria., PMID:39858919

Shrimp White Spot Viral Infections Are Attenuated by Organic Acids by Regulating the Expression of HO-1 Oxygenase and β-1,3-Glucan-Binding Protein., PMID:39857423

Anti-Inflammatory Effects of Cannabigerol In Vitro and In Vivo Are Mediated Through the JAK/STAT/NFκB Signaling Pathway., PMID:39851511

Exploration of the Topical Nanoemulgel Bearing with Ferulic Acid and Essential Oil for Diabetic Wound Healing., PMID:39728684

Interleukin-22 promotes endometrial carcinoma cell proliferation and cycle progression via ERK1/2 and p38 activation., PMID:39690293

Lifitegrast, a Lymphocyte Function-Associated Antigen-1 Antagonist Demonstrates Beneficial Effect in Psoriasis., PMID:39676586

Th22 cells promote the transition from homeostatic to reactive microglia in diabetic encephalopathy., PMID:39630234

Human Umbilical Cord Mesenchymal Stem Cell-Derived Exosomes Loaded Mir-29-3p Targets AhR to Improve Juvenile Idiopathic Arthritis via Inhibiting the Expression of IL-22 in CD4+ T Cell., PMID:39621151

Harnessing a Safe Novel Lipid Nanoparticle: Targeted Oral Delivery to Colonic Epithelial and Macrophage Cells in a Colitis Mouse Model., PMID:39591041

Stilbene-enriched extract from the leaves of Cajanus cajan attenuates psoriasis in imiquimod-induced psoriatic mice by targeting aryl hydrocarbon receptor and chemokines., PMID:39547364

Pristimerin Alleviates DSS-Induced Colitis in Mice by Modulating Intestinal Barrier Function, Gut Microbiota Balance and Host Metabolism., PMID:39538091

NKp46+ ILC3s promote early neutrophil defense against Clostridioides difficile infection through GM-CSF secretion., PMID:39475653

Dihydroberberine alleviates Th17/Treg imbalance in premature ovarian insufficiency mice via inhibiting Rheb/mTOR signaling., PMID:39472803

In Situ Expression of Yak IL-22 in Mammary Glands as a Treatment for Bovine Staphylococcus aureus-Induced Mastitis in Mice., PMID:39453107

Intestinal Epithelial PTPN2 Limits Pathobiont Colonization by Immune-Directed Antimicrobial Responses., PMID:39386684

Role of HIF-1α-Activated IL-22/IL-22R1/Bmi1 Signaling Modulates the Self-Renewal of Cardiac Stem Cells in Acute Myocardial Ischemia., PMID:39264501

Lactiplantibacillus plantarum Regulates Intestinal Physiology and Enteric Neurons in IBS through Microbial Tryptophan Metabolites., PMID:39082086

Involucrasin B suppresses airway inflammation in obese asthma by inhibiting the TLR4-NF-κB-NLRP3 pathway., PMID:39029138

Momordin Ic ameliorates psoriasis skin damage in mice via the IL-23/IL-17 axis., PMID:39007937

Discovery of novel chrysin derivatives as potential Anti-Psoriasis agents., PMID:38955004

[Study on the protection of gingival epithelial barrier by interleukin-22 through regulating microbiota and E-cadherin expression]., PMID:38949133

A cytokine-like factor 1 homolog acts as a macrophage chemoattractant in grass carp., PMID:38925447

Innate lymphoid cell-based immunomodulatory hydrogel microspheres containing Cutibacterium acnes extracellular vesicles for the treatment of psoriasis., PMID:38871203

Gallic acid attenuates murine ulcerative colitis by promoting group 3 innate lymphocytes, affecting gut microbiota, and bile acid metabolism., PMID:38844081

Fluorescent Labeling and Imaging of IL-22 mRNA-Loaded Lipid Nanoparticles., PMID:38798981

PI3K inhibitor "alpelisib" alleviates methotrexate induced liver injury in mice and potentiates its cytotoxic effect against MDA-MB-231 triple negative breast cancer cell line., PMID:38797265

Bacterial Sphingolipids Exacerbate Colitis by Inhibiting ILC3-derived IL-22 Production., PMID:38704148

A CTCF-binding site in the Mdm1-Il22-Ifng locus shapes cytokine expression profiles and plays a critical role in early Th1 cell fate specification., PMID:38697116

RORγt inverse agonist TF-S14 inhibits Th17 cytokines and prolongs skin allograft survival in sensitized mice., PMID:38609465

IL-22 signaling promotes sorafenib resistance in hepatocellular carcinoma via STAT3/CD155 signaling axis., PMID:38596684

Sialic Acid Mediated Endothelial and Hepatic Uptake: A Mechanism based Mathematic Model Elucidating the Complex Pharmacokinetics and Pharmacodynamics of Efmarodocokin Alfa, a Variably Glycosylated Fusion Protein., PMID:38561054

Interleukin-22 inhibits cardiac fibrosis by regulating fibroblast metabolic reprogramming in myocardial infarction., PMID:38492359

Aryl Hydrocarbon Receptor Regulates Muc2 Production Independently of IL-22 during Colitis., PMID:38397081

Corticosteroids impair epithelial regeneration in immune-mediated intestinal damage., PMID:38349762

Roles of tumor necrosis factor-like ligand 1A in γδT-cell activation and psoriasis pathogenesis., PMID:38348035

Fraxin (7-hydroxy-6-methoxycoumarin 8-glucoside) confers protection against ionizing radiation-induced intestinal epithelial injury in vitro and in vivo., PMID:38335653

The antidepressive mechanism of Longya Lilium combined with Fluoxetine in mice with depression-like behaviors., PMID:38218856

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