Dendritic cell targeting in lymph nodes with modular adapters boosts HAdV5 and HC-HAdV5 tumor vaccination by co-secretion of IL-2v and IL-21., PMID:40487484
Anti-viral CD8 central memory veto cells as a new platform for CAR T cell therapy., PMID:40448965
Interleukin-37 Suppresses the Function of Type 2 Follicular Helper T in Allergic Rhinitis., PMID:40427088
The Combination of Oncolytic Virus and Antibody Blockade of TGF-β Enhances the Efficacy of αvβ6-Targeting CAR T Cells Against Pancreatic Cancer in an Immunocompetent Model., PMID:40361460
IL-21 Loading CaMnCO3 Vitality Backpacks Boost CAR-T Cell Synergistic Immunotherapy., PMID:40345978
IL-21R-Targeted Nano-immunosuppressant Prevents Acute Rejection in Allogeneic Transplantation by Blocking Maturation of T Follicular Helper Cells., PMID:40339970
Andrographolide sulfonate alleviates rheumatoid arthritis by inhibiting glycolysis-mediated activation of PI3K/AKT to restrain Th17 cell differentiation., PMID:40274350
Interleukin-21 engineering enhances CD19-specific CAR-NK cell activity against B-cell lymphoma via enriched metabolic pathways., PMID:40176196
PLK1 Mediates the Proliferation and Contraction of Airway Smooth Muscle Cells and Has a Role in T2-High Asthma with Neutrophilic Inflammation Model., PMID:40162075
Syndecans and glycosaminoglycans influence B-cell development and activation., PMID:40155751
IL-21 promotes plasmablast differentiation independently of proliferation in vitro., PMID:39924005
Immune profiling of human vestibular schwannoma secretions identifies TNF-α and TWEAK as cytokines with synergistic potential to impair hearing., PMID:39923035
Combinatorial immunotherapy with anti-ROR1 CAR NK cells and an IL-21 secreting oncolytic virus against neuroblastoma., PMID:39895691
Chimeric cytokine receptor TGF-β RⅡ/IL-21R improves CAR-NK cell function by reversing the immunosuppressive tumor microenvironment of gastric cancer., PMID:39884449
Plasma membrane-coated nanoparticles and membrane vesicles to orchestrate multimodal antitumor immunity., PMID:39864848
Dual neutralization of TGF-β and IL-21 regulates Th17/Treg balance by suppressing inflammatory signalling in the splenic lymphocytes of Staphylococcus aureus infection-induced septic arthritic mice., PMID:39831928
GM-CSF and IL-21-armed oncolytic vaccinia virus significantly enhances anti-tumor activity and synergizes with anti-PD1 immunotherapy in pancreatic cancer., PMID:39830516
IL-35 modulates Tfh2 and Tfr cell balance to alleviate allergic rhinitis., PMID:39825933
IL-21 shapes the B cell response in a context-dependent manner., PMID:39792552
Carbonic anhydrase 2-derived drug-responsive domain regulates membrane-bound cytokine expression and function in engineered T cells., PMID:39789216
Immune Checkpoint Blockade Delays Cancer Development and Extends Survival in DNA Polymerase Mutator Syndromes., PMID:39786467
Polyfunctional IL-21+ IFNG+ T follicular helper cells contribute to checkpoint inhibitor diabetes mellitus and can be targeted by JAK inhibitor therapy., PMID:39677814
Potent antitumor activity of a designed interleukin-21 mimic., PMID:39677740
Inborn errors of immunity reveal molecular requirements for generation and maintenance of human CD4+ IL-9-expressing cells., PMID:39622295
TCR-CD3 signal strength regulates plastic coexpression of IL-4 and IFN-γ in Tfh-like cells., PMID:39582865
Gynostemma pentaphyllum saponins shield mice from peanut allergy by modulation of gut microbiota: A novel approach for peanut allergy management., PMID:39522254
[In Vitro Amplification of NK Cells from Feeder Layer Cells Expressing IL-21]., PMID:39479851
FoxO1/Rictor axis induces a nongenetic adaptation to ibrutinib via Akt activation in chronic lymphocytic leukemia., PMID:39436708
Three hepcidins from the spotted knifejaw (Oplegnathus punctatus) promote antimicrobial activity via TLR/NFκB pathway., PMID:39396559
Targeted therapy of multiple myeloma by IL21-NKG2D CAR-T cells., PMID:39373147
Pharmacodynamic and pharmacokinetic study of Shaoyao Gancao decoction for repairing intestinal barrier damage in ulcerative colitis., PMID:39369520
VSIG4 induces the immunosuppressive microenvironment by promoting the infiltration of M2 macrophage and Tregs in clear cell renal cell carcinoma., PMID:39260310
IL-21- and CXCL9-engineered GPC3-specific CAR-T cells combined with PD-1 blockade enhance cytotoxic activities against hepatocellular carcinoma., PMID:39196390
Interleukin-21 engineering enhances NK cell activity against glioblastoma via CEBPD., PMID:39137729
Ex vivo model of breast cancer cell invasion in live lymph node tissue., PMID:39091774
IL-21 Shapes the B Cell Response in a Context-Dependent Manner., PMID:39026745
Mesenchymal stem cells-derived extracellular vesicles ameliorate lupus nephritis by regulating T and B cell responses., PMID:39020448
A "Prime and Expand" strategy using the multifunctional fusion proteins to generate memory-like NK cells for cell therapy., PMID:38960949
Mechanism of Prunella vulgaris L. and luteolin in restoring Tfh/Tfr balance and alleviating oxidative stress in Graves' disease., PMID:38879922
Selective production of IL-33-neutralizing autoantibody ameliorates asthma responses and severity., PMID:38740111
Immunomodulation of Ethyl pyruvate on gestational diabetes mellitus in Mice; The impact on Th17/Treg balance., PMID:38663253
A novel engineered IL-21 receptor arms T-cell receptor-engineered T cells (TCR-T cells) against hepatocellular carcinoma., PMID:38643203
Dynamic Hybrid Module-Driven NK Cell Stimulation and Release for Tumor Immunotherapy., PMID:38639407
Latent Epstein-Barr virus infection collaborates with Myc over-expression in normal human B cells to induce Burkitt-like Lymphomas in mice., PMID:38620028
RORγt inverse agonist TF-S14 inhibits Th17 cytokines and prolongs skin allograft survival in sensitized mice., PMID:38609465
The IL-21/IL-21R signaling axis regulates CD4+ T-cell responsiveness to IL-12 to promote bacterial-induced colitis., PMID:38498592
Building a Better Defense: Expanding and Improving Natural Killer Cells for Adoptive Cell Therapy., PMID:38474415
A novel lentiviral vector-based approach to generate chimeric antigen receptor T cells targeting Aspergillus fumigatus., PMID:38415653
Harnessing the cytotoxic granule exocytosis to augment the efficacy of T-cell-engaging bispecific antibody therapy., PMID:38268493
Co-expression of IL-21-Enhanced NKG2D CAR-NK cell therapy for lung cancer., PMID:38263004
For research use only. Not for human or drug use.
