InVivoMAb Anti-Human IL10 (Iv0025)

Catalog No.

VHD50701

Species reactivity

Human

Host species

Mouse

Isotype

IgG1, kappa

Clonality

Monoclonal

Target

IL-10, IL10, Cytokine synthesis inhibitory factor, CSIF, Interleukin-10

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P22301

Applications

ELISA, Neutralization

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

Iv0025

Armored human CAR Treg cells with PD1 promoter-driven IL-10 have enhanced suppressive function., PMID:40512855

Platelet DKK1 promotes tolerogenic dendritic cells and non-healing responses in cutaneous leishmaniasis., PMID:40502169

Controlled delivery of immunomodulatory factors for mineralized tissue formation in an inflammatory microenvironment., PMID:40502164

Comparative efficacy of Naringenin and Sinomenine in facilitating the differentiation of mouse hematopoietic stem cells into immature dendritic cells to promote transplantation immunological regulation., PMID:40499621

Therapeutic Impact of Polysaccharide from Chinese Yam (Dioscorea opposita Thunb) on DSS-Induced Ulcerative Colitis in Mice., PMID:40498533

Secretome enriched with small extracellular vesicles derived from human gingiva-derived mesenchymal stem cells enhances rat tongue muscle regeneration., PMID:40495198

Intranasal delivery of platelet cell membrane-cloaked Astragaloside IV loaded biomimetic nanoparticles for enhanced therapeutics in acute lung injury mice., PMID:40494449

Combined effects of IRAK inhibition and pioglitazone on hepatic inflammation and apoptosis in a mouse model of MASLD., PMID:40493096

Ginsenoside Rg1 alleviates PCPA-induced insomnia by inhibiting NLRP3 inflammasome activation and pyroptosis through the Nrf2/HO-1 pathway in mice., PMID:40493075

A Pilot Randomized Trial of Home-Based, Video-Supervised Exercise on Muscle Metabolism and Physical Endurance in Chronic Kidney Disease., PMID:40492069

miR-125a-5p Regulates Treg Function by Targeting Foxp3 in Experimental Autoimmune Myasthenia Gravis Mice., PMID:40490083

Potentially Elevated Rheumatoid Arthritis Risk due to Chemotherapy-Induced Inflammation in Prostate Cancer With Bone Metastasis., PMID:40489190

High doses of the galactooligosaccharides, 2'-fucosyllactose alleviate immunodeficiency in vitro and in vivo., PMID:40488907

Amiodarone and Ravuconazole Combination Potentiates Chemotherapy against Drug-Resistant Trypanosoma cruzi Strains., PMID:40488037

Anti-inflammatory effects of Rehmannia glutinosa polysaccharide on LPS-induced acute liver injury in mice and related underlying mechanisms., PMID:40484254

Exploring the anti-inflammatory effects of total flavonoids from L. gracile on LPS-induced inflammation: An integrated approach combining network pharmacology, molecular docking, and experimental validation., PMID:40483832

Semaphorin 7A Induces Liver Inflammation and Promotes Parenteral Nutrition-Associated Cholestasis via ITGβ1/NF-κB Pathway., PMID:40483769

Thymoquinone modulates oxidative stress and inflammation, correcting mercury-induced HO-1/NRF/Trx pathway disruption in experimental rat hepatorenal system: an in vivo and in silico study., PMID:40481309

PDPK1 governs macrophage M2 polarization via hypoxia-driven CD47/AKT-glycolytic Axis in endometriosis., PMID:40480430

Levistilide A attenuates carbon tetrachloride (CCl4)-induced liver fibrosis by inhibiting the NF-κB/iNOS/NO signalling pathway in M1 macrophages., PMID:40480397

A targeted pH-responsive micelle based on poly (ethylene glycol) and polycaprolactone for Pseudomonas aeruginosa pneumonia treatment., PMID:40480000

PD-1-dependent therapeutic effect of Trichinella spiralis cystatin on myocardial infarction in a mice model., PMID:40474292

Transglutaminase 2-expressing macrophages modulate adipose tissue inflammation., PMID:40467990

Effects of intracerebroventricular lipopolysaccharide administration on behavioral, neurochemical, and neurogenomic responses in adult zebrafish., PMID:40466776

The Role of Formononetin in Cerebral Ischemia-Reperfusion Injury: A New Mediator of c-Fos/IL-10/STAT3 Signaling Pathway., PMID:40464507

[Polysaccharide extract PCP1 from Polygonatum cyrtonema ameliorates cerebral ischemia-reperfusion injury in rats by inhibiting TLR4/NLRP3 pathway]., PMID:40461201

The role of immune checkpoint molecules in PRRSV-2-induced immune modulation: insights from comparative in vivo evaluation including NADC34-like PRRSV., PMID:40459260

Nuclear S100A9 Protein Induces Anti-Inflammatory Gene Expression in Sepsis., PMID:40458301

Effect of statins on IL-10 signaling and production by chronic lymphocytic leukemia cells., PMID:40456521

Prostaglandin E2 receptor EP4 activation induces tolerogenic dendritic cells to mitigate ischemic acute kidney injury., PMID:40450025

Inhibition of head and neck squamous cell carcinoma by Bruton's tyrosine kinase inhibitor ibrutinib is associated with reduction of immunosuppressive T cells., PMID:40445239

Effects of higenamine on M1/M2 polarization and osteoclast differentiation in rheumatoid arthritis via the THBS-1/TGF-β signaling pathway., PMID:40441469

Curcumin combined with arsenic trioxide enhances autophagy and immune surveillance to inhibit immune escape in acute myeloid leukemia., PMID:40440957

Ethnopharmacological and scientific validation of Caryota mitis Lour fruit peel for osteoarthritis and gout management., PMID:40436126

Systems Biology-Driven Discovery of Host-Targeted Therapeutics for Oropouche Virus: Integrating Network Pharmacology, Molecular Docking, and Drug Repurposing., PMID:40430433

Multitargeted Effects of Plantago ovata Ethanol Extract in Experimental Rat Streptozotocin-Induced Diabetes Mellitus and Letrozole-Induced Polycystic Ovary Syndrome., PMID:40429855

Comparative Analysis of Cytokine Expression Profiles in Prostate Cancer Patients., PMID:40427694

Therapeutic Potential of Lythrum salicaria L. Ethanol Extract in Experimental Rat Models of Streptozotocin-Induced Diabetes Mellitus and Letrozole-Induced Polycystic Ovary Syndrome., PMID:40427455

In Vitro Evaluation of the PMN Reaction on a Collagen-Based Purified Reconstituted Bilayer Matrix (PRBM) Using the Autologous Blood Concentrate PRF., PMID:40427065

FGF-21 fusion proteins ameliorate atopic dermatitis by inhibiting the TLR/TSLP signaling pathway: Anti-inflammatory and skin barrier repair effects., PMID:40424659

An Elastase Inhibitor ShSPI from Centipede Attenuates Bleomycin-Induced Pulmonary Fibrosis., PMID:40423296

Human Amniotic Fluid-Derived Exosomes Alleviate Neuropathic Pain by Inducing an Anti-Inflammatory Transition in Microglia., PMID:40417920

Nesfatin-1 Suppresses Inflammation in Bronchopulmonary Dysplasia by Regulating HMGB-1/TLR4/p65/NLRP3 Signaling Pathway., PMID:40415368

Protective Effect of Resveratrol Against Peri-Implant Inflammation and Oxidative Stress: An in vivo Study., PMID:40415361

Microarray Patch Based Transdermal Allergen Immunotherapy Prevents Gliadin-induced Anaphylaxis in a Murine Model., PMID:40414810

Therapeutic potential of plant-derived small extracellular vesicles in sepsis: A network meta-analysis., PMID:40414583

A galactoglucomannan from Termitomyces intermedius: Structural characterization, anti-obesity and anti-inflammatory activities., PMID:40414582

Rapamycin-modified CD169low/-tolDC promotes skin graft survival in mice via IL-10+Breg., PMID:40414462

Cell therapy with human IL-10-producing ILC2s enhances islet function and inhibits allograft rejection., PMID:40412656

Earthworm extract improves cerebral ischemia-reperfusion injury through regulating microglia polarization and promoting cerebral angiogenesis in vitro and in vivo., PMID:40412587

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