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InVivoMAb Anti-Human IL5 (Iv0021)

Catalog #:   VHC13601 Specific References (50) DATASHEET
Host species: Human
Isotype: IgG1, kappa
Applications: ELISA, Neutralization
Accession: P05113
Overview

Catalog No.

VHC13601

Species reactivity

Human

Host species

Human

Isotype

IgG1, kappa

Clonality

Monoclonal

Target

IL5, B-cell differentiation factor I, IL-5, T-cell replacing factor, TRF, Eosinophil differentiation factor, Interleukin-5

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P05113

Applications

ELISA, Neutralization

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

Iv0021

Data Image
  • Western Blot
    Various lysates were subjected to SDS PAGE followed by western blot with Anti Human IL5 antibody [Iv0021] (VHC13601) at 1μg/ml.

    Lane 1: Human IL5 transfected HEK293 cell lysate
    Lane 2: Non-transfected HEK293 cell lysate

    Second Ab: Goat Anti-Human IgG H&L Polyclonal antibody, HRP (PHB96431) at 0.1 μg/mL.

References

A Novel Small Molecule ITK Inhibitor Suppresses Th2/Th17 Differentiation and Attenuates Airway Inflammation in a Mouse Model of HDM-Induced Asthma., PMID:40509664

Modulating Dendritic Cell function in Allergic Asthma with Toxoplasma gondii serine-protease inhibitor 1., PMID:40489241

Amygdalin Alleviates Airway Inflammation and Remodeling in Asthma Mice: Involvement of TGF-β1/Smads Signaling Pathway., PMID:40485525

Network pharmacology and experimental validation of inflammation inhibition by ChuanKeZhi Injection in treating asthma., PMID:40450983

Comparative Analysis of Cytokine Expression Profiles in Prostate Cancer Patients., PMID:40427694

Microarray Patch Based Transdermal Allergen Immunotherapy Prevents Gliadin-induced Anaphylaxis in a Murine Model., PMID:40414810

Therapeutic potential of Platycodin D in allergic asthma through anti-inflammatory and anti-remodeling effects., PMID:40397997

Exosomes derived from M2 macrophages regulate airway inflammation by modulating epithelial cell proliferation and apoptosis., PMID:40390011

Transcriptional co-regulator OCA-B/Pou2af1 restricts Th2 differentiation., PMID:40364837

Exploring the potential of Moringa oleifera seed extract-loaded microemulsion hydrogel in the DNCB-induced atopic dermatitis model., PMID:40347408

PGC-1α agonist ZLN005 ameliorates OVA-induced asthma in BALB/c mice through modulating the NF-κB-p65/NLRP3 pathway., PMID:40343297

High expression of ITGB3 ameliorates asthma by inhibiting epithelial-mesenchymal transformation through suppressing the activation of NF-kB pathway., PMID:40263524

Glucocorticoid receptor inhibits Th2 immune responses by down-regulating Pparg and Gata3 in schistosomiasis., PMID:40196108

The RNA-binding protein KSRP reduces asthma-like characteristics in a murine model., PMID:40095032

N-Acetylcysteine and Its Therapeutic Potential in an Animal Model of Allergic Asthma., PMID:40094443

Antiviral roles of eosinophils in asthma and respiratory viral infection., PMID:40083723

Lactobacillus acidophilus TW01 Mitigates PM2.5-Induced Lung Injury and Improves Gut Health in Mice., PMID:40077701

HGF-DPSCs ameliorate asthma by regulating CCR1+ Th2 cells responses in mice pulmonary mucosa., PMID:40072405

Phenolic Preservatives Are Not the Sole Cause of Eosinophilic Infiltration at Infusion Pump Sites., PMID:40067457

Anti-IL-5 treatment, but not neutrophil interference, attenuates inflammation in a mixed granulocytic asthma mouse model, elicited by air pollution., PMID:39875874

Migrasomes derived from human umbilical cord mesenchymal stem cells: a new therapeutic agent for ovalbumin-induced asthma in mice., PMID:39865246

Pharmacological validation of a novel exopolysaccharide from Streptomyces sp. 139 to effectively inhibit cytokine storms., PMID:39816356

CD131 antagonism blocks inflammation, emphysema and fibrosis in an asthma-COPD overlap mouse model originating in early life., PMID:39814691

Fibroblast growth factor 21 alleviated atopic march by inhibiting the differentiation of type 2 helper T cells., PMID:39798471

Amelioration of Inflammation in Rats with Experimentally Induced Asthma by Spenceria ramalana Trimen Polyphenols via the PI3K/Akt Signaling Pathway., PMID:39796021

Effects of Earthworm (Pheretima communisima) extract on atopic dermatitis: An in vitro and in vivo study., PMID:39758409

The bitter flavor of Banxia Xiexin decoction activates TAS2R38 to ameliorate low-grade inflammation in the duodenum of mice with functional dyspepsia., PMID:39746410

CTSS contributes to airway neutrophilic inflammation in mixed granulocytic asthma., PMID:39719614

Hsa_circRNA_100791 Modulates Trim13 Through Sponging miR-487b-5p to Facilitate Inflammation in Allergic Rhinitis., PMID:39713717

Xuanhong Dingchuan Tang suppresses bronchial asthma inflammation via the microRNA-107-3p/PTGS2/MAPK axis., PMID:39704779

SPA14 liposomes combining saponin with fully synthetic TLR4 agonist provide adjuvanticity to hCMV vaccine candidate., PMID:39702373

Interleukin-38-overexpressing adenovirus infection in dendritic cell-based treatment enhances immunotherapy for allergic asthma via inducing Foxp3+ regulatory T cells., PMID:39667222

Assessment of dermal sensitization by nickel salts in a novel humanized TLR-4 mouse model., PMID:39632339

Parasympathetic Airway Hyperreactivity Is Enhanced in Acute but Not Chronic Eosinophilic Asthma Mouse Models., PMID:39626221

Remodeling of Il4-Il13-Il5 locus underlies selective gene expression., PMID:39567762

LRRC8A drives NADPH oxidase-mediated mitochondrial dysfunction and inflammation in allergic rhinitis., PMID:39550567

Quercetin inhibits ferroptosis through the SIRT1/Nrf2/HO-1 signaling pathway and alleviates asthma disease., PMID:39524399

Efficient In Vitro Plasma Cell Differentiation by B Cell Receptor Activation and Cytokine Stimulation., PMID:39513030

Group 2 innate lymphocytes protect the balance between autophagy and apoptosis in cardiomyocytes during sepsis-induced cardiac injury., PMID:39443633

The efficacy and potential mechanism of the acupuncture treatment for allergic rhinitis: A systematic review and meta-analysis of data from animal models., PMID:39403524

Prevention and alleviation of allergic rhinitis by oral administration of Lacticaseibacillus paracasei GOLDGUT-Lpc969., PMID:39403377

Interleukin-5 as a pleiotropic cytokine orchestrating airway type 2 inflammation: Effects on and beyond eosinophils., PMID:39359069

Perinatal administration of Saccharomyces cerevisiae UFMG A-905 prevents asthma development in the offspring of mice., PMID:39353595

HPV16 mutant E6/E7 construct is protective in mouse model., PMID:39350162

In vivo screening of flavonoid compounds revealed quercetin as a potential drug to improve recovery of angiostrongyliasis after albendazole treatment., PMID:39348380

Type XVII Collagen-Specific CD4+ T Cells Induce Bullous Pemphigoid by Producing IL-5., PMID:39326663

Pseudomonas aeruginosa exotoxin A as a novel allergen induced Non-TH2 inflammation in a murine model of steroid-insensitive asthma., PMID:39315215

Myricetin ameliorates airway inflammation and remodeling in asthma by activating Sirt1 to regulate the JNK/Smad3 pathway., PMID:39299094

UFMylation is involved in serum inflammatory cytokines generation and splenic T cell activation induced by lipopolysaccharide., PMID:39276536

Silencing TRIM8 alleviates allergic asthma and suppressing Th2 differentiation through inhibiting NF-κB/NLRP3 signaling pathway., PMID:39260527

Datasheet
$ 372
Product specifications
100 μg 372 1 mg 1486

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For research use only. Not for human or drug use.

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InVivoMAb Anti-Human IL5 (Iv0021) [VHC13601]
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