Gut Microbiota-Derived Butyric Acid Alleviates Glucocorticoid-Associated Osteonecrosis of the Femoral Head via Modulating Inflammatory Cytokines in Bone Marrow Mesenchymal Stem Cells., PMID:40510588
Comparative efficacy of Naringenin and Sinomenine in facilitating the differentiation of mouse hematopoietic stem cells into immature dendritic cells to promote transplantation immunological regulation., PMID:40499621
Long-acting IL-2 release from pressure-fused biomineral tablets promotes antitumor immune response., PMID:40494938
Characterization and biological evaluation of melatonin-loaded silk fibroin-hyaluronic acid films for multifunctional wound dressings., PMID:40494453
Growth of human regulatory CD4+ T cells is more tightly controlled than effector T cells due to distinctive molecular programming., PMID:40491491
Anti-TNFR2 antibody and HMGN1 combined with TIL cell therapy inhibits colorectal cancer progression by enhancing immune response., PMID:40483876
Spatially Tuned Localization of Interleukins and OX40 Agonists Enhances Synergistic Anti-Tumor Immunity., PMID:40475557
New mouse model based on adenocarcinoma 4T1 cells expressing HPV16 E6 and E7 applied to assess the efficacy of therapeutic and prophylactic E6/E7-based HPV16 vaccines., PMID:40470197
Effect of statins on IL-10 signaling and production by chronic lymphocytic leukemia cells., PMID:40456521
Expression of an interleukin-2 partial agonist enhances regulatory T cell persistence and efficacy in mouse autoimmune models., PMID:40425532
Health-related effects of byproducts from the food industry within in vivo models: a systematic review., PMID:40400178
Synergistic anti-tumor effects of mRNA vaccine and PERK inhibitor combination in melanoma treatment., PMID:40383023
The Combination of Oncolytic Virus and Antibody Blockade of TGF-β Enhances the Efficacy of αvβ6-Targeting CAR T Cells Against Pancreatic Cancer in an Immunocompetent Model., PMID:40361460
Development and Potent Anti-Tumor Activity of a Fully Humanized Anti-TAG-72-IL-2 Fusion Protein for Therapy of Solid Tumors., PMID:40361381
A Colombian strain of Clostridioides difficile ribotype 002 induces a highly inflammatory response in a mouse infection model., PMID:40355394
Luminescent mouse model of endometriosis: three-dimensional morphology of lesions and cytokine profiles., PMID:40350305
Tilianin regulates the proliferation, invasion and tumor immune microenvironment of thyroid cancer cells through the TLR4/NF-κB axis., PMID:40349407
Leafing a mark on immunity: Quercetin-3-O-D-glucopyranoside and quercetin-3-O-(2″,6″-digalloyl)-β-D-galactopyranoside-rich Melia azedarach L. extract's immunoinflammatory effects on an sRBC-immunized BALB/c model., PMID:40345340
HIF-PH inhibitors induce pseudohypoxia in T cells and suppress the growth of microsatellite stable colorectal cancer by enhancing antitumor immune responses., PMID:40343532
Generating potent and persistent antitumor immunity via affinity-tuned CAR-T cells targeting mesothelin., PMID:40341217
Development of a nano-vaccine for high-grade serous ovarian cancer., PMID:40338561
KIF22 promotes the proliferation and immune escape of endometrial cancer cells by activating the STAT3/PDL1 pathway., PMID:40326230
4-Octyl Itaconate Modulates Dendritic Cells Function and Tumor Immunity via NRF2 Activation., PMID:40322530
The effect of heat-inactivated BBMN68 on immune regulation and gut microbiota in immunosuppressed mice and exploration of its immunomodulation postbiotic functional components., PMID:40316116
Regulatory T cells suppress GM-CSF-producing T helper cells via IL-2 modulation to restrain immunopathology., PMID:40315053
Immunomodulatory potential of phosphorus: insights from experimental mice models under normal and immunosuppressive condition., PMID:40294527
Enhanced HIV immune responses elicited by an apoptotic single-cycle SHIV lentivector DNA vaccine., PMID:40292218
IL-2-independent expansion, persistence, and antitumor activity in TIL expressing regulatable membrane-bound IL-15., PMID:40285351
Bioinformatics analysis reveals CTSF suppresses tumor cell malignant phenotype and CD8 + T cell exhaustion by downregulating Bcl- 2 protein in the microenvironment of bladder cancer., PMID:40278892
IL-10 alleviates aTCMR by inhibiting NFATc1 signaling pathway of T cells after kidney transplantation., PMID:40268206
Exploring the mechanism of esculetin extracted from Chroogomphus rutilus in treating liver cancer based on network pharmacology, molecular docking, and in vivo experimental validation., PMID:40254108
Effect of physical modification on the immunomodulatory activity of carboxymethyl pachymaran., PMID:40253046
Adjuvant dendritic cell-based immunotherapy in melanoma: insights into immune cell dynamics and clinical evidence from a phase II trial., PMID:40251644
Novel PD-1-targeted, activity-optimized IL-15 mutein SOT201 acting in cis provides antitumor activity superior to PD1-IL2v., PMID:40250867
Amuc_1434 From Akkermansia muciniphila Enhances CD8+ T Cell-Mediated Anti-Tumor Immunity by Suppressing PD-L1 in Colorectal Cancer., PMID:40231387
The Anti-Cancer Role of Pterostilbene in Endometrial Cancer: A Phase II Prospective, Randomized, Window-of-Opportunity Clinical Trial with Megestrol Acetate., PMID:40227411
Design of a peptide-based vaccine against human respiratory syncytial virus using a reverse vaccinology approach: evaluation of immunogenicity, antigenicity, allergenicity, and toxicity., PMID:40226615
Acasunlimab, an Fc-inert PD-L1×4-1BB bispecific antibody, combined with PD-1 blockade potentiates antitumor immunity via complementary immune modulatory effects., PMID:40216443
Breaking the scar barrier: The anti-fibrotic and hemodynamic benefits of total salvianolic acid in hypertrophic scars., PMID:40216314
Discovery of novel JAK3 inhibitors for the treatment of atopic dermatitis., PMID:40216205
Synthesis of new selective agents with dual anti-inflammatory and SARS-CoV-2 Mpro inhibitory activity: Antipyrine-celecoxib hybrid analogues; COX-2, COVID-19 cytokine storm and replication inhibitory activities., PMID:40199011
Revolutionizing Chikungunya Vaccines: mRNA Breakthroughs With Molecular and Immune Simulations., PMID:40182080
[Identification of genes regulating human CAR-T cell proliferation by genome-wide CRISPR screening]., PMID:40175136
CD45-mediated apoptosis and IL-2 receptor downregulation by serine proteases secreted from diarrheagenic bacteria., PMID:40166318
Direct delivery of immune modulators to tumour-infiltrating lymphocytes using engineered extracellular vesicles., PMID:40154979
Self-luminous nanoengineered bacteria with the sustained release of interleukin 2 as an in situ vaccine for enhanced cancer immunotherapy., PMID:40154768
Anti-CD137 agonist antibody-independent and clinically feasible preparation of tumor-infiltrating lymphocytes from soft tissue sarcoma and osteosarcoma., PMID:40145091
Selective activation of interleukin-2/interleukin-15 receptor signaling in tumor microenvironment using paired bispecific antibodies., PMID:40132909
Enhanced Antitumor Immunity Through T Cell Activation with Optimized Tandem Double-OX40L mRNAs., PMID:40125432
Rational design, optimization, and biological evaluation of novel pyrrolo-pyridone derivatives as potent and orally active Cbl-b inhibitors., PMID:40120499
For research use only. Not for human or drug use.
