Catalog No.
VMK25201
Species reactivity
Mouse
Host species
Mouse
Isotype
IgG1, kappa
Clonality
Monoclonal
Target
CD16, CD32, Low affinity immunoglobulin gamma Fc region receptor III, IgG Fc receptor III, Fc-gamma RIII, FcRIII, CD16, Fcgr3, Low affinity immunoglobulin gamma Fc region receptor II, Fc gamma receptor IIB, Fc-gamma RII, Fc-gamma-RIIB, FcRII, IgG Fc receptor II beta, Lymphocyte antigen 17, Ly-17, CD32, Fcgr2, Fcgr2b, Ly-17
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P08508, P08101
Applications
Neutralization
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
Iv0016
Combined treatment with anti-PSMA antibody and human peripheral blood-derived NK cells for castration-resistant prostate cancer., PMID:40469300
Embryonic mast cells arise from the Cpa3-expressing precursors but not granulocyte-monocyte progenitors., PMID:40419842
Lycium barbarum glycopeptide alleviates retinal inflammation by suppressing microglial M1 polarization via NF-κB/MAPK pathways., PMID:40412789
Earthworm extract improves cerebral ischemia-reperfusion injury through regulating microglia polarization and promoting cerebral angiogenesis in vitro and in vivo., PMID:40412587
Splenic CD169+Tim4+ Marginal Metallophilic Macrophages Are Essential for Wound Healing After Myocardial Infarction., PMID:40289811
Fc-mediated immune stimulating, pro-inflammatory and antitumor effects of anti-HER2 IgE against HER2-expressing and trastuzumab-resistant tumors., PMID:40074330
Feeder-cell-free system for ex vivo production of natural killer cells from cord blood hematopoietic stem and progenitor cells., PMID:40051631
TREM2 promotes hippocampal neurogenesis through regulating microglial M2 polarization in APP/PS1 mice., PMID:40049315
Spermine delivered by ZIF90 nanoparticles alleviates atherosclerosis by targeted inhibition of macrophage ferroptosis in plaque., PMID:40038689
The CD64/CD28/CD3ζ chimeric receptor reprograms T-cell metabolism and promotes T-cell persistence and immune functions while triggering antibody-independent and antibody-dependent cytotoxicity., PMID:39962623
Antibody-Dependent Cellular Cytotoxicity of iPS Cell-Derived Natural Killer T Cells by Anti-GD2 mAb for Neuroblastoma., PMID:39916425
Hydroxysafflor yellow A attenuates the inflammatory response in cerebral ischemia-reperfusion injured mice by regulating microglia polarization per SIRT1-mediated HMGB1/NF-κB signaling pathway., PMID:39798476
CD70-targeted iPSC-derived CAR-NK cells display potent function against tumors and alloreactive T cells., PMID:39793572
In Situ Proefferocytosis Microspheres as Macrophage Polarity Converters Accelerate Osteoarthritis Treatment., PMID:39780612
The novel CD16A/anti-CD3 bifunctional protein, eCD16A/anti-CD3-BFP, redirects T cell cytotoxicity toward antibody-bound target cells., PMID:39763374
TIM3 on natural killer cells regulates antibody-dependent cellular cytotoxicity in HER2-positive gastric cancer., PMID:39722406
Modified CD15/CD16-CLL1 inhibitory CAR-T cells for mitigating granulocytopenia toxicities in the treatment of acute myeloid leukemia., PMID:39647325
Activation of receptor-independent fluid-phase pinocytosis promotes foamy monocyte formation in atherosclerotic mice., PMID:39615283
Quercetin alleviates neonatal hypoxic-ischaemic brain injury by rebalancing microglial M1/M2 polarization through silent information regulator 1/ high mobility group box-1 signalling., PMID:39565473
PF4 inhibits ferroptosis-mediated intracerebral hemorrhage through modulating the CXCR3/AKT1/SLC7A11 signaling pathway., PMID:39558855
A pump-free microfluidic co-culture system for investigating NK cell-tumor spheroid interactions in flow conditions., PMID:39549923
A PSMA-Targeted Tri-Specific Killer Engager Enhances NK Cell Cytotoxicity against Prostate Cancer., PMID:39545924
Interleukin-12 decorated nanosized semiflexible Immunofilaments enable directed targeting and augmented IFNγ responses of natural killer cells., PMID:39528061
Impact of site-specific conjugation strategies on the pharmacokinetics of antibody conjugated radiotherapeutics., PMID:39378827
Biomimetic Iron-Based Nanoparticles Remodel Immunosuppressive Tumor Microenvironment for Metabolic Immunotherapy., PMID:39286354
Curcumin loaded hydrogel with double ROS-scavenging effect regulates microglia polarization to promote poststroke rehabilitation., PMID:39211291
Association Between Cytokeratin 19-Specific IgG and Neutrophil Activation in Asthma., PMID:39155736
Enhanced IL-15-mediated NK cell activation and proliferation by an ADAM17 function-blocking antibody involves CD16A, CD137, and accessory cells., PMID:39053944
A high affinity monoclonal antibody against HLA-E-VL9 enhances natural killer cell anti-tumor killing., PMID:39026709
CLADIN- CLADribine and INnate immune response in multiple sclerosis - A phase IV prospective study., PMID:38964633
A "Prime and Expand" strategy using the multifunctional fusion proteins to generate memory-like NK cells for cell therapy., PMID:38960949
ACE2 decoy Fc-fusions and bi-specific killer engager (BiKEs) require Fc engagement for in vivo efficacy against SARS-CoV-2., PMID:38948747
A subpopulation of tissue remodeling monocytes stimulates revascularization of the ischemic limb., PMID:38896604
In Vivo PET Imaging of 89Zr-Labeled Natural Killer Cells and the Modulating Effects of a Therapeutic Antibody., PMID:38844362
TGF-β signalling limits effector function capacity of NK cell anti-tumour immunity in human bladder cancer., PMID:38810560
Enhanced IL-15-mediated NK cell activation and proliferation by an ADAM17 function-blocking antibody involves CD16A, CD137, and accessory cells., PMID:38798522
Targeting tumor cell-to-macrophage communication by blocking Vtn-C1qbp interaction inhibits tumor progression via enhancing macrophage phagocytosis., PMID:38773982
Quantifying Antibody-Dependent Cellular Cytotoxicity in a Tumor Spheroid Model: Application for Drug Discovery., PMID:38738886
Early recovery of natural killer cells post T-cell depleted allogeneic stem cell transplantation using alemtuzumab "in the bag"., PMID:38641148
Induction of NK cell reactivity against acute myeloid leukemia by Fc-optimized CD276 (B7-H3) antibody., PMID:38637557
Mesenchymal Stem Cells Regulate Microglial Polarization via Inhibition of the HMGB1/TLR4 Signaling Pathway in Diabetic Retinopathy., PMID:38625640
Microglia and macrophages alterations in the CNS during acute SIV infection: a single-cell analysis in rhesus macaques., PMID:38617282
Targeting sinonasal undifferentiated carcinoma with a combinatory immunotherapy approach., PMID:38593586
scRNA-seq analysis discovered suppression of immunomodulatory dependent inflammatory response in PMBCs exposed to silver nanoparticles., PMID:38494495
Bispecific immune cell engager enhances the anticancer activity of CD16+ NK cells and macrophages in vitro, and eliminates cancer metastasis in NK humanized NOG mice., PMID:38490714
Large-scale bioreactor production of extracellular vesicles from mesenchymal stromal cells for treatment of acute radiation syndrome., PMID:38475968
T-cell help in the tumor microenvironment enhances rituximab-mediated NK-cell ADCC., PMID:38457360
Immunocapture of cell surface proteins embedded in HIV envelopes uncovers considerable virion genetic diversity associated with different source cell types., PMID:38412143
Systems Analysis of Immune Changes after B-cell Depletion in Autoimmune Multiple Sclerosis., PMID:38370778
Tetrahydrocurcumin Protects Against GSK3β/PTEN/PI3K/Akt-Mediated Neuroinflammatory Responses and Microglial Polarization Following Traumatic Brain Injury., PMID:38368289
For research use only. Not for human or drug use.
