Purified Human AS Fc Block™ (SAA0280)

Catalog No.

FHK25310

Species reactivity

Human

Host species

Human

Isotype

IgG1, kappa

Clonality

Monoclonal

Conjugation

Unconjugated

Target

CD16, CD32, Low affinity immunoglobulin gamma Fc region receptor III, IgG Fc receptor III, Fc-gamma RIII, FcRIII, CD16, Fcgr3, Low affinity immunoglobulin gamma Fc region receptor II, Fc gamma receptor IIB, Fc-gamma RII, Fc-gamma-RIIB, FcRII, IgG Fc receptor II beta, Lymphocyte antigen 17, Ly-17, CD32, Fcgr2, Fcgr2b, Ly-17, Fc Block

Concentration

1.41 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Applications

Fc Blocking, FCM

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

SAA0280

Soluble Factors and Mechanisms Regulated by Sialylated IgG Signaling., PMID:40084926

Antithrombotic efficacy and bleeding risks of vaccine-induced immune thrombotic thrombocytopenia treatments., PMID:39293086

[A recombinant adeno-associated virus expressing secretory TGF-β type Ⅱ receptor inhibits triple-negative murine breast cancer 4T1 cell proliferation and lung metastasis in mice]., PMID:38862439

Characterization of a Trispecific PD-L1 Blocking Antibody That Exhibits EGFR-Conditional 4-1BB Agonist Activity., PMID:38804302

Development of a Bispecific IgG1 Antibody Targeting BCMA and PDL1., PMID:38390876

Functional integration of protein A binding ability to antibody fragments for convenient and tag-free purification., PMID:37732741

Bioengineered peptibodies as blockers of ion channels., PMID:36475947

SARS-CoV-2 spike protein variant binding affinity to an angiotensin-converting enzyme 2 fusion glycoproteins., PMID:36472974

Development of a Novel HTLV-1 Protease: Human Fcγ1 Recombinant Fusion Molecule in the CHO Eukaryotic Expression System., PMID:36399306

Notch1 and Notch4 core binding domain peptibodies exhibit distinct ligand-binding and anti-angiogenic properties., PMID:36376768

Preclinical characterization and clinical translation of pharmacodynamic markers for MK-5890: a human CD27 activating antibody for cancer immunotherapy., PMID:36100308

IgG Binds Escherichia coli Serine Protease EspP and Protects Mice From E. coli O157:H7 Infection., PMID:35250980

Preparation and characterization of a high-affinity monoclonal antibody against nerve growth factor., PMID:34627999

Age Related Response of Neonatal Rat Retinal Ganglion Cells to Reduced TrkB Signaling in vitro and in vivo., PMID:34150766

Pre-Existing Humoral Immunity Enhances Epicutaneously-Administered Allergen Capture by Skin DC and Their Migration to Local Lymph Nodes., PMID:33868229

Thrombotic Thrombocytopenia after ChAdOx1 nCov-19 Vaccination., PMID:33835769

First Report of Dieback Caused by Neofusicoccum batangarum in Cashew in Guinea-Bissau., PMID:33258426

Ultrasensitive detection of anti-p53 autoantibodies based on nanomagnetic capture and separation with fluorescent sensing nanobioprobe for signal amplification., PMID:33032195

Preclinical Evaluation of an Engineered Single-Chain Fragment Variable-Fragment Crystallizable Targeting Human CD44., PMID:32513906

Generation of a neutralizing antibody against RD114-pseudotyped viral vectors., PMID:31702531

Blocking the PD-1-PD-L1 axis by a novel PD-1 specific nanobody expressed in yeast as a potential therapeutic for immunotherapy., PMID:31495493

Elimination of erroneous results related to bovine mononuclear cell immunophenotyping by antibodies binding to Fc receptors., PMID:31307671

An IgG-induced neutrophil activation pathway contributes to human drug-induced anaphylaxis., PMID:31292264

GLUT1 and GLUT3 involvement in anthocyanin gastric transport- Nanobased targeted approach., PMID:30692585

Cytotoxic anti-circumsporozoite antibodies target malaria sporozoites in the host skin., PMID:30349082

Cardioprotective Role of Myeloid-Derived Suppressor Cells in Heart Failure., PMID:29437117

Aminoacylase 3 Is a New Potential Marker and Therapeutic Target in Hepatocellular Carcinoma., PMID:29290764

Uromodulin p.Cys147Trp mutation drives kidney disease by activating ER stress and apoptosis., PMID:28990932

Differential influences of Fc gamma receptor blocking on the effects of certolizumab pegol and infliximab on human monocytes., PMID:28805137

Intact CD100-CD72 Interaction Necessary for TCR-Induced T Cell Proliferation., PMID:28713384

Splenomegaly, myeloid lineage expansion and increased osteoclastogenesis in osteogenesis imperfecta murine., PMID:28600151

Expression, Purification, and Biophysical Characterization of a Secreted Anthrax Decoy Fusion Protein in Nicotiana benthamiana., PMID:28054967

Dimeric and Trimeric Fusion Proteins Generated with Fimbrial Adhesins of Uropathogenic Escherichia coli., PMID:27843814

Human isotype-dependent inhibitory antibody responses against Mycobacterium tuberculosis., PMID:27729388

Elimination of erroneous results in flow cytometry caused by antibody binding to Fc receptors on human monocytes and macrophages., PMID:27731950

LDL receptor-related protein 1 contributes to the clearance of the activated factor VII-antithrombin complex., PMID:27614059

Development of an automated mid-scale parallel protein purification system for antibody purification and affinity chromatography., PMID:27498022

Characterization and high-yield production of non-N-glycosylated recombinant human BCMA-Fc in Pichia pastoris., PMID:32624756

Antibody-mediated neutralization of autocrine Gas6 inhibits the growth of pancreatic ductal adenocarcinoma tumors in vivo., PMID:27170265

A novel regulation of PD-1 ligands on mesenchymal stromal cells through MMP-mediated proteolytic cleavage., PMID:27141350

Purified and Recombinant Hemopexin: Protease Activity and Effect on Neutrophil Chemotaxis., PMID:26772775

A novel human truncated IL12rβ1-Fc fusion protein ameliorates experimental autoimmune encephalomyelitis via specific binding of p40 to inhibit Th1 and Th17 cell differentiation., PMID:26384304

Anti-infective immunoadhesins from plants., PMID:26242703

Structure of the omalizumab Fab., PMID:25849503

Baculovirus display for discovery of low-affinity extracellular receptor-ligand interactions using protein microarrays., PMID:25797350

IgM and IgA rheumatoid factors purified from rheumatoid arthritis sera boost the Fc receptor- and complement-dependent effector functions of the disease-specific anti-citrullinated protein autoantibodies., PMID:25769920

Ameliorative Effects of p75NTR-ED-Fc on Axonal Regeneration and Functional Recovery in Spinal Cord-Injured Rats., PMID:25394381

Antibody blocks acquisition of bacterial colonization through agglutination., PMID:24962092

Blocking monocyte transmigration in in vitro system by a human antibody scFv anti-CD99. Efficient large scale purification from periplasmic inclusion bodies in E. coli expression system., PMID:24798881

Construction and characterization of an enhanced GFP-tagged TIM-1 fusion protein., PMID:24444999

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