Catalog No.
EHJ93601
Expression system
Mammalian Cells
Species
Homo sapiens (Human)
Protein length
[Arg20-Pro189] & [Ile23-Ser328]
Predicted molecular weight
Reduced: 20 kDa & 44 kDa; Nonreduced: 60 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9NPF7 & P29460
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Interleukin-23, IL23, IL-23
Insights for lncH19, miR-9, and miR-146a expression levels and their cross-talk with pro-inflammatory cytokines, copeptin, and neopterin profile in type 1 diabetic cardiomyopathy., PMID:40512257
Dietary lipids induce PPARd and BCL6 to repress macrophage IL-23 induction after intestinal injury and LPS exposure., PMID:40502773
Adipose-Derived Mesenchymal Stromal/Stem Cells Reduce Inflammatory Responses and Partially Alleviate Skin Symptoms in Imiquimod-Induced Psoriasis-Like Dermatitis Model Mice., PMID:40500215
Interleukin-23 Inhibitors for Inflammatory Bowel Disease: Pivotal Trials and Practical Considerations., PMID:40465057
A tryptophol-containing emulgel ameliorates imiquimod-induced mice psoriasis., PMID:40461662
Profiling of fecal analytes as a potential biomarker in rheumatoid arthritis., PMID:40458399
The relationship between interleukin and ankylosing spondylitis., PMID:40440969
Engineering a protease-stable, oral single-domain antibody to inhibit IL-23 signaling., PMID:40434646
JAK-STAT inhibitors in noninfectious uveitis - A review., PMID:40434456
Targeting the IL-23 Receptor Gene: A Promising Approach in Inflammatory Bowel Disease Treatment., PMID:40429917
A hybrid protocol for peptide development: integrating deep generative models and physics simulations for biomolecular design targeting IL23R/IL23., PMID:40419055
Functional role of Annexin A1 and S100A11 in psoriasis pathogenesis: Insights from IMQ-induced models and keratinocyte modulation., PMID:40409105
Differential Expression of Th17-Related Cytokines in Patients of Chronic Kidney Disease with and Without Systemic Lupus Erythematosus., PMID:40407212
The 'totality of evidence' and 'extrapolation' of SB17, a ustekinumab biosimilar., PMID:40396611
Interleukin-23p19 inhibitors for the treatment of moderate-to-severe psoriasis: an expert opinion of real-world evidence studies in Europe., PMID:40396610
Clinical insights into IL-23 inhibition: risankizumab for Crohn's disease through a systematic review and meta-analysis of randomized controlled trials., PMID:40395763
With guselkumab, does the dual mechanisms to inhibit IL-23, help in ulcerative colitis?, PMID:40394835
Gut-heart axis: cardiac remodeling and heart failure in the context of inflammatory bowel disease and dysbiosis., PMID:40387516
Anti-IL-12/23p40 antibodies for induction of remission in Crohn's disease., PMID:40357993
Deucravacitinib in patients with inflammatory bowel disease: 12-week efficacy and safety results from 3 randomized phase 2 studies in Crohn's disease and ulcerative colitis., PMID:40355364
Experimental verification of Myriocin molecular bioactivity in revoking rheumatoid arthritis: New emphasis on S100A1 repression and PPAR-γ activation via non-canonical pathways in the flare-up of cytokines., PMID:40354710
Effect of cholecalciferol on immune and vascular function in non-diabetic chronic kidney disease., PMID:40342405
Early Prediction of Acute Gastrointestinal Injury in Patients with Acute Pancreatitis by C-reactive Protein/Albumin Ratio Combined with IL-23., PMID:40340888
Predictors of Immunogenicity and Loss of Response to ANTI-TNFα Therapy in Crohn Disease-A Systematic Review., PMID:40338684
Immunomodulatory effects of dental pulp stem cells on lymphocytes and monocytes from patients with rheumatoid arthritis., PMID:40338061
Longitudinal lipoprotein and inflammatory mediators analysis uncover persisting inflammation and hyperlipidemia following SARS-CoV-2 infection in long COVID-19., PMID:40335840
Pharmacological inhibition of tyrosine protein-kinase 2 reduces islet inflammation and delays type 1 diabetes onset in mice., PMID:40335415
Weathering the Storm: How Age and Biologics Influence the COVID-19 Cytokine Surge., PMID:40333142
One-Year Efficacy of Guselkumab Versus Advanced Therapies for the Treatment of Moderately to Severely Active Crohn's Disease: A Network Meta-Analysis., PMID:40327280
Differentiating IL-23 Inhibitors in Crohn's Disease., PMID:40323342
Serum Concentrations of IL-18, IL-21, IL-22, IL-23, IL-27, and IL-31 in Patients With Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis and Their Correlation With Disease Severity., PMID:40322299
Paradoxical Activation of Entheseal Myeloid Cells by JAK1 and TYK2 Inhibitors via IL10 Antagonism., PMID:40320905
Maternal Immune Activation During Pregnancy and Obstetric Outcomes: A Population-Based Cohort Study., PMID:40313214
Advances in genetic-immunological targeted therapies for psoriasis., PMID:40311222
Stepwise neofunctionalization of the NF-κB family member Rel during vertebrate evolution., PMID:40307452
Platelet-derived microvesicles modulate cytokine and lipid mediator profiles in THP-1 monocytes and macrophages., PMID:40306329
Complex evaluation of coagulation, fibrinolysis, and inflammatory cytokines in SARS-CoV-2 infected pregnant women: a prospective, case-control study., PMID:40303405
Interventions in cytokine signaling: novel horizons for psoriasis treatment., PMID:40303401
Efficacy and safety of Mirikizumab for ulcerative colitis: a systematic review and meta-analysis of randomized controlled trials., PMID:40301737
Novel Small-Molecule Treatment and Emerging Biological Therapy for Psoriasis., PMID:40299379
Multiplex immunofluorescence assessment of macrophages and IL-23R in inflammatory and malignant diseases of the oral mucosa: a pilot study., PMID:40297579
Differences in the gut and pharyngeal microbiomes before and after treatment of an acute exacerbation of chronic obstructive pulmonary disease., PMID:40288425
Vildagliptin topical ointment: an effective treatment for imiquimod-induced psoriasis in mice., PMID:40285915
Chrysin improves endothelial inflammation via the NFAT pathway in Kawasaki disease., PMID:40285837
IL-17 and IL-23 inhibitors dose spacing in adult psoriatic patients: a real-world pilot study., PMID:40285562
IL-17A-producing NKp44(-) group 3 innate lymphoid cells accumulate in Familial Adenomatous Polyposis duodenal tissue., PMID:40280932
Toll-like receptors and inflammatory cytokines in the skin of Acanthamoeba spp. infected immunocompetent and immunosuppressed mice., PMID:40274043
Accelerating and protective effects toward cancer growth in cGAS and FcgRIIb deficient mice, respectively, an impact of macrophage polarization., PMID:40272597
Changes in the Immune Profile and Chromatin Accessibility of Peripheral Regulatory T Cells in Psoriasis Patients Before and After Treatment With Biologics., PMID:40269508
The role of interleukin inhibitors in the treatment of hidradenitis suppurativa; a systematic review of clinical trials., PMID:40268126
For research use only. Not for human or drug use.
