Research Grade Anti-Human IFNG/IFN-gamma (AMG 811)

Catalog No.

DHB95403

Expression system

Mammalian Cells

Species reactivity

Human

Host species

Human

Isotype

IgG

Clonality

Monoclonal

Applications

Research Grade Biosimilar

Target

Interferon gamma, IFN-gamma, Immune interferon, IFNG

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P01579

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Alternative Names

AMG-811, AMG 811, AMG811

Clone ID

AMG 811

Note

For research use only. Not suitable for clinical or therapeutic use.

Pharmacokinetic and pharmacodynamic relationship of AMG 811, an anti-IFN-γ IgG1 monoclonal antibody, in patients with systemic lupus erythematosus., PMID:25213774

Targeting interferons in systemic lupus erythematosus: current and future prospects., PMID:25940912

Blockade of interferon-γ normalizes interferon-regulated gene expression and serum CXCL10 levels in patients with systemic lupus erythematosus., PMID:26138472

Update on clinical trials in systemic lupus erythematosus., PMID:27314466

Brief Report: Pharmacodynamics, Safety, and Clinical Efficacy of AMG 811, a Human Anti-Interferon-γ Antibody, in Patients With Discoid Lupus Erythematosus., PMID:28118537

Safety, pharmacokinetics and pharmacodynamics of AMG 811, an anti-interferon-γ monoclonal antibody, in SLE subjects without or with lupus nephritis., PMID:29018537

Document Download

Research Grade Anti-Human IFNG/IFN-gamma (AMG 811).pdf