Catalog No.
EHC95701
Expression system
Insect Cells
Species
Homo sapiens (Human)
Protein length
Met1-Leu536
Predicted molecular weight
61.25 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P12931
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Proto-oncogene tyrosine-protein kinase Src, 2.7.10.2, Proto-oncogene c-Src, pp60c-src, p60-Src, SRC, SRC1
E-Cadherin: A conductor of cellular signaling., PMID:40513205
Network Pharmacology and Molecular Docking-Based Approach to Explore Potential Bioactive Compounds from Kaempferia parviflora on Chemokine Signaling Pathways in the Treatment of Psoriasis Disease., PMID:40508056
Elucidating the Anti-Diabetic Mechanisms of Mushroom Chaga (Inonotus obliquus) by Integrating LC-MS, Network Pharmacology, Molecular Docking, and Bioinformatics., PMID:40508014
Association between Lyn tyrosine kinase and renal injury in patients with systemic lupus erythematosus., PMID:40506261
Integrating metabolomics and network pharmacology analysis provides new insights into the lipid metabolism disorder of Abrus mollis., PMID:40505757
Zinc-mediated dynamics of CD4/CD8α co-receptors and Lck kinase: Implications for zinc homeostasis, immune response, and biotechnological innovations., PMID:40504517
RNF213-Dependent EGFR and HER2 Activation Regulates Specific Downstream Signaling Pathways in Human Cancer Cells., PMID:40503863
Curcumenol Inhibits Mast Cells Activation in Ovalbumin-Induced Anaphylaxis Model Mice through Modulation of the Fc Epsilon Receptor I Signaling Pathway., PMID:40503570
PD-1 is conserved from sharks to humans: new insights into PD-1, PD-L1, PD-L2, and SHP-2 evolution., PMID:40503235
Computational design of conformation-biasing mutations to alter protein functions., PMID:40501788
Evaluating First-Pass, High Protein Capacity Desalting Techniques For Phosphoproteomics Applications., PMID:40501759
Csk-mediated Src family kinase regulation dampens neutrophil infiltration during pulmonary infection., PMID:40493407
USP4-mediated deubiquitination of SRC-1 regulates macrophage polarization and asthma inflammation., PMID:40493388
Puerarin Improves Cancer-Induced Bone Pain by Recovering Mitochondrial Dysfunction in the Spinal Cord., PMID:40493135
Network pharmacology and molecular docking-based characterization of the mechanisms through which Astragali Radix-Atractylodes macrocephala Koidz herb pair can treat membranous nephropathy., PMID:40489804
Uncovering the effects of ATBC plasticizers on intracerebral hemorrhage outcomes based on network toxicology and in vitro and in vivo experimental validation., PMID:40482445
Co-targeting SRC overcomes resistance to BRAF inhibitors in colorectal cancer., PMID:40481178
Identification of potential therapeutic targets and epithelial cell signaling pathway for Helicobacter pylori infection using biosurfactants as a novel green antimicrobials: A network pharmacology approach., PMID:40480449
1-O-Acetylbritannilactone exerts anti-inflammatory and anti-MUC5AC effects by targeting PKC-α and downregulating the SRC/EGFR/MAPK signaling pathway., PMID:40480001
Unraveling anti-atherosclerosis mechanism of anthocyanins from Xinjiang wild cherry plum (Prunus divaricata Ledeb) via network pharmacology and molecular docking., PMID:40478326
Improved anti-breast cancer activity through structural modification of fused pyran derivatives and mechanistic investigations., PMID:40475243
Congenital Pseudarthrosis of the Tibia: A Comprehensive Literature Review., PMID:40472164
Rational Design and Protein Engineering of {SH2 Domain-≫ Flexible Linker-≫ Self-Controlling Peptide} Fusion System With Phosphorylation-Regulated Molecular Switch Functionality., PMID:40468592
A Naturally Derived Glycosylated Oleanolic Acid Derivative Suppresses NF-κB Translocation and Induces Intrinsic Apoptosis in Lung Adenocarcinoma Cells., PMID:40468424
FXYD2 marks and regulates maturity of β cells via ion channel-mediated signal transduction., PMID:40467586
IFITM1 promotes proliferation, migration and macrophage-like transdifferentiation of vascular smooth muscle cells via c-Src/MAPK/GATA2/E2F2 pathway in atherosclerosis., PMID:40466954
Nickel binding to c-Src SH3 domain facilitates crystallization., PMID:40463187
Computational design of dynamic biosensors for emerging synthetic opioids., PMID:40462994
R2HaPpY: Rapid-robust phosphotyrosine peptide enrichment using HaloTag-Src SH2 pY superbinder., PMID:40462989
Unusually Broad-spectrum small-molecule sensing using a single protein scaffold., PMID:40462935
CD200R1-CD200 checkpoint inhibits phagocytosis differently from SIRPα-CD47 to suppress tumor growth., PMID:40461553
Efflux of N1-acetylspermidine from hepatoma fosters macrophage-mediated immune suppression to dampen immunotherapeutic efficacy., PMID:40460833
Focal adhesion kinase promotes ribosome biogenesis to drive advanced thyroid cancer cell growth and survival., PMID:40458728
Paridis Rhizoma Saponins ameliorate CCl4-induced liver fibrosis via modulation of the Nrf2-HO-1/NQO-1 and TGF-β1/Smads signaling pathways., PMID:40458200
Hantaan virus activates Src family kinase and induces endothelial cell hyperpermeability via the TLR4/TRAF6 pathway., PMID:40455573
Novel therapeutic targets for metabolism-related diseases: proteomic Mendelian randomization and colocalization analyses., PMID:40453312
Network pharmacology and experimental validation of inflammation inhibition by ChuanKeZhi Injection in treating asthma., PMID:40450983
Study on the Chemical Composition, Biological Activity, and Mechanism of Intervention in Erectile Dysfunction of Healthy Snow Lotus Wine., PMID:40443781
Siglec6 CAR T cells suppressed progression of AML via inhibiting Siglec6 and SHP2 induced Src and ERK signaling activation., PMID:40436895
DAB2 binds to LASP1 to participate in migration and invasion of non-small cell lung cancer through TGF-β/Smad pathway., PMID:40436729
An electrostatic network with strong connectivity is a phospho-sensor for regulating affinity of Syk-receptor association., PMID:40434649
Intercepting the Downstream of the Estrogen Receptor Signaling Pathway: Discovery of a Potent and Efficient SRC-3 PROTAC Degrader for Overcoming Endocrine Resistance Breast Cancer., PMID:40434408
Exploring the allosteric effect of SHP2 Tyr62 phosphorylation on the emergence of acquired resistance to allosteric inhibitor SHP099., PMID:40432314
High-Risk Neuroblastoma Stage 4 (NBS4): Developing a Medicinal Chemistry Multi-Target Drug Approach., PMID:40430383
Pericarpium Trichosanthis Injection Protects Isoproterenol-Induced Acute Myocardial Ischemia via Suppressing Inflammatory Damage and Apoptosis Pathways., PMID:40427511
Integrative in silico and in vivo Drosophila model studies reveal the anti-inflammatory, antioxidant, and anticancer properties of red radish microgreen extract., PMID:40425671
Synergistic blockade of SHP-2 and A2AR signal pathways with targeted nanoparticles restores anti-tumor immunity of CD8+ T cells., PMID:40425093
Shared molecular mechanisms of bisphenol A and phthalates in endometriosis: A bioinformatics and molecular docking study., PMID:40424730
Molecular Targets and Mechanisms of Piperine Against Breast Cancer: A Network Pharmacology, Molecular Docking Analysis, and Toxicity Prediction., PMID:40424641
The Effects of Neuronal Fyn Knockdown in the Hippocampus in the Rat Kainate Model of Temporal Lobe Epilepsy., PMID:40422246
For research use only. Not for human or drug use.
